RAIDS atlas of significant genetic and protein biomarkers in cervical cancer
Loss of function in epigenetic acting genes together with driver alterations in the PIK3CA pathway have been shown significantly associated with poor outcome in cervical squamous cell cancer. More recently, a CoxBoost analysis identified 16 gene alterations and 30 high level activated proteins to be of high interest, due to their association with ...
Suzy Scholl +3 more
openaire +2 more sources
Effects of occipital-atlas stabilization in the upper cervical spine kinematics: an in vitro study [PDF]
AbstractThis study compares upper cervical spine range of motion (ROM) in the three cardinal planes before and after occiput-atlas (C0–C1) stabilization. After the dissection of the superficial structures to the alar ligament and the fixation of C2, ten cryopreserved upper cervical columns were manually mobilized in the three cardinal planes of ...
Hidalgo García, César +9 more
openaire +5 more sources
Posterior midline cleft of the atlas – a crucial anatomical variation in vertebral fractures
The anatomy of the first vertebra, namely atlas, has significant clinical implications. Atlas is situated between the occipital bone and the second cervical vertebra (axis) and is one of the main points of head movement.
Serghei Covantev +3 more
doaj +1 more source
Cryptic complexity in felid vertebral evolution: shape differentiation and allometry of the axial skeleton [PDF]
Members of the mammalian family Felidae (extant and extinct cats) are grossly phenotypically similar, but display a 300-fold range in body size, from less than 1 kg to more than 300 kg.
Alvarez +85 more
core +3 more sources
Dystopic Os odontoideum: A rare cause of atlantoaxial instability
Os odontoideum is a relatively common developmental anomaly of the craniovertebral junction (CVJ), which is usually an incidental finding on spine imaging. But the dystopic variety of os odontoideum is uncommon and can be baleful.
Joe M Das, K Krishnakumar, Suresh Nair
doaj +1 more source
Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication. [PDF]
The transcription factor Yin Yang 1 (YY1) is frequently overexpressed in cancerous tissues compared to normal tissues and has regulatory roles in cell proliferation, cell viability, epithelial-mesenchymal transition, metastasis and drug/immune resistance.
Bonavida, Benjamin +2 more
core +2 more sources
OBJETIVO: Apresentar os resultados cirúrgicos de uma série de casos de estabilização da coluna cervical superior com o uso de parafusos de massa lateral do atlas.
Enrico Ghizoni +3 more
doaj +1 more source
Giant petrous bone cholesteatoma: combined microscopic surgery and an adjuvant endoscopic approach [PDF]
Petrous bone cholesteatomas (PBCs) are epidermoid cysts, which have developed in the petrous portion of the temporal bone and may be congenital or acquired.
Iannella, Giannicola +4 more
core +1 more source
The Transspinal Canal Screwing Technique for Atlantoaxial Anomalies: A Technical Note and 2 Case Reports [PDF]
It is difficult to treat atlantoaxial instability in patients with a high-riding vertebral artery or anomalies of the craniocervical junction. We report 2 successful cases in which the transspinal canal screwing technique was used because of difficulties
Kento Takebayashi +4 more
doaj +1 more source
Cervical Spinal Stenosis and Myelopathy Due to Atlas Hypoplasia
This paper describes a patient who presented at our hospital with neurologic symptoms due to congenital cervical spinal stenosis at the atlas level. Congenital atlantal stenosis is usually due to hypoplasia of the posterior arch of the atlas. It is a rare cause of spinal stenosis, and only 12 symptomatic patients with isolated atlantal stenosis have ...
Hsu, Yu-Hone +5 more
openaire +2 more sources

