RAIDS atlas of significant genetic and protein biomarkers in cervical cancer
Loss of function in epigenetic acting genes together with driver alterations in the PIK3CA pathway have been shown significantly associated with poor outcome in cervical squamous cell cancer. More recently, a CoxBoost analysis identified 16 gene alterations and 30 high level activated proteins to be of high interest, due to their association with ...
Suzy Scholl +3 more
openaire +2 more sources
Cervical Myelopathy Caused by a Split Atlas Anomaly: A Case Report [PDF]
An 18-year-old male presented with a 6-month history of paresthesia of both arms and legs after a minor neck trauma. CT scan revealed a partial aplasia of the anterior and posterior arches of the C1 vertebra resulting in a split atlas. MRI showed an intramedullary high-signal area. We performed a posterior decompressive laminectomy and occipitocervical
Mehdi Meddeb +4 more
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OBJETIVO: Apresentar os resultados cirúrgicos de uma série de casos de estabilização da coluna cervical superior com o uso de parafusos de massa lateral do atlas.
Enrico Ghizoni +3 more
doaj +1 more source
The Transspinal Canal Screwing Technique for Atlantoaxial Anomalies: A Technical Note and 2 Case Reports [PDF]
It is difficult to treat atlantoaxial instability in patients with a high-riding vertebral artery or anomalies of the craniocervical junction. We report 2 successful cases in which the transspinal canal screwing technique was used because of difficulties
Kento Takebayashi +4 more
doaj +1 more source
Cervical Spinal Stenosis and Myelopathy Due to Atlas Hypoplasia
This paper describes a patient who presented at our hospital with neurologic symptoms due to congenital cervical spinal stenosis at the atlas level. Congenital atlantal stenosis is usually due to hypoplasia of the posterior arch of the atlas. It is a rare cause of spinal stenosis, and only 12 symptomatic patients with isolated atlantal stenosis have ...
Hsu, Yu-Hone +5 more
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Magnetic Resonance Imaging Atlas-Based Volumetric Mapping of the Cervical Cord Gray Matter in Cervical Canal Stenosis [PDF]
White matter volume loss may be an anatomic driver in the development of clinical symptoms in cervical spondylotic myelopathy (CSM). Considerably less attention has been devoted to gray matter (GM) injury. Newly developed atlas-based mapping techniques may allow evaluation of GM cord volume alterations in CSM.There were 29 subjects evaluated: 15 ...
Zachary A, Smith +9 more
openaire +2 more sources
Fracture of the Atlas through a Synchondrosis of Anterior Arch
Cervical fractures are rare in paediatric population. In younger children, cervical fractures usually occur above the level of C4; whereas in older population, fractures or dislocations more commonly involve the lower cervical spine.
Gamze Turk +2 more
doaj +1 more source
The Evaluation of Skeletal Age Based on Computer-Supported Methods in Comparison to the Atlas Method
This article describes methods used in estimating skeletal age based both on the evaluation of skeletal maturation of the palm and the wrist (Greulich and Pyle’s atlas method) and the Cervical Vertebral Maturation method (CVM).
Predko-Maliszewska Anna +2 more
doaj +1 more source
Cervical Myelopathy Secondary to Atlas Hypoplasia - Reports of 3 Adult Cases - [PDF]
There have been paucity of reports on atlas hypoplasia, and as a result this condition is not clearly defined, nor well understood. The authors reported three cases of atlas hypoplasia that were found in adults who presented with myelopathic symptoms.
Chang, Han +6 more
openaire +2 more sources
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source

