Results 91 to 100 of about 5,357,473 (408)

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source

CACA guidelines for vulvar malignancies

Holistic Integrative Oncology
Objective The purpose of this study is to provide reference and guidance for the clinical diagnosis and treatment of vulvar malignancies. Method This article sorts out and integrates the contents of vulvar malignancies in the field of traditional Chinese
Zhongqiu Lin, Huaiwu Lu, Jing Wang, Xiaofei Tian, Tao Zhu, Bin Li, Kaijiang Liu, Danbo Wang, Yuhao Zhang, Lingling Xie   +9 more
doaj   +1 more source

Upaya Peningkatan Cakupan Deteksi Dini Kanker Serviks dengan KarS-A (Kartu Skor Aim) pada WUS Ranting ‘Aisyiyah Socah Bangkalan

Caradde, 2023
This community service aims to increase WUS knowledge and attitudes about cervical cancer and increase WUS motivation to carry out early detection of cervical cancer.
A’im Matun Nadhiroh, Annisa Wigati Rozifa, Fulatul Anifah, Awwalul Wiladatil Qodliyah   +3 more
doaj   +1 more source

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

Molecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock, Lina Benzien, Sandra Lange, Maja Huehns, Alexandra Runge, Catrin Roolf, Anett Sekora, Gudrun Knuebel, Hugo Murua Escobar, Christian Junghanss, Anna Richter   +10 more
wiley   +1 more source

Expanding management strategies for cervical precancerous lesions in resource-limited settings: insights from a training center in a district hospital in Ghana

BMC Women's Health
Background Cervical cancer continues to disproportionately burden women in low/middle-income countries like Ghana. We examined treatment patterns and histopathological outcomes among women screened using visual inspection with acetic acid (VIA) and/or ...
Kofi Effah, Ethel Tekpor, Comfort Mawusi Wormenor, Samuel Adolf Bosoka, Maxwell Afetor, Anita Edinam Dugbazah, Stephen Danyo, Esu Aku Catherine Morkli, Georgina Tay, Bernard Hayford Atuguba, Elorm Kpofo-Tetteh, Chrysantus Kubio, Nana Owusu Mensah Essel   +12 more
doaj   +1 more source

CerviXpert: A Multi-Structural Convolutional Neural Network for Predicting Cervix Type and Cervical Cell Abnormalities [PDF]

DIGITAL HEALTH, Vol. 10, 2024,
Cervical cancer is a major cause of cancer-related mortality among women worldwide, and its survival rate improves significantly with early detection. Traditional diagnostic methods such as Pap smears and cervical biopsies rely heavily on cytologist expertise, making the process prone to human error. This study introduces CerviXpert, a multi-structural
arxiv   +1 more source

NCCN Guidelines Insights: Cervical Cancer, Version 1.2020.

The Journal of the National Comprehensive Cancer Network, 2020
The NCCN Guidelines for Cervical Cancer provide recommendations for diagnostic workup, staging, and treatment of patients with the disease. These NCCN Guidelines Insights focus on recent updates to the guidelines, including changes to first- and second ...
N. Abu-Rustum, C. Yashar, S. Bean, K. Bradley, S. Campos, H. Chon, C. Chu, D. Cohn, M. Crispens, S. Damast, C. Fisher, P. Frederick, D. Gaffney, R. Giuntoli, E. Han, W. Huh, John R. Lurain III, A. Mariani, D. Mutch, C. Nagel, L. Nekhlyudov, A. Fader, S. Remmenga, R. Reynolds, R. Sisodia, T. Tillmanns, S. Ueda, R. Urban, E. Wyse, Nicole R Mcmillian, Angela Motter   +30 more
semanticscholar   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

Tingkat Pengetahuan, Sikap dan Perilaku Mahasiswi Fakultas Kedokteran Universitas Sumatera Utara Tentang Kanker Serviks

Jurnal Kesehatan Andalas, 2022
Cervical cancer is the fourth most common cancer among women worldwide. It can be prevented by HPV vaccination, pap smears examination, or avoidance of risk factors for cervical cancer. Objectives.
Savira Laniari Putri, Feby Yanti Harahap
doaj   +1 more source

CerviFormer: A Pap-smear based cervical cancer classification method using cross attention and latent transformer [PDF]

arXiv, 2023
Purpose: Cervical cancer is one of the primary causes of death in women. It should be diagnosed early and treated according to the best medical advice, as with other diseases, to ensure that its effects are as minimal as possible. Pap smear images are one of the most constructive ways for identifying this type of cancer.
arxiv