Results 101 to 110 of about 708,585 (354)

Carvacrol instigates intrinsic and extrinsic apoptosis with abrogation of cell cycle progression in cervical cancer cells: Inhibition of Hedgehog/GLI signaling cascade [PDF]

, 2023
Afza Ahmad, Rohit Kumar Tiwari, Mοhd Saeed, Hadba Al-Amrah, Ihn Han, Eun Ha Choi, Dharmendra Kumar Yadav, Irfan Ahmad Ansari   +7 more
openalex   +1 more source

Photoactivated Proximity Protein Labeling Reveals Enhanced Tumor Retention of a D‐Peptide‐Ruthenium Prodrug Conjugate

Advanced Healthcare Materials, EarlyView.
Six stereoisomeric ruthenium‐peptide conjugates were synthesized and characterized, which showed high potential in photoactivated chemotherapy (PACT) and proximity protein labeling. Abstract Amino acid chirality is known to influence the biological properties of peptide‐containing prodrugs.
Liyan Zhang, Peiyuan Wang, Hildert Bronkhorst, Yurii Husiev, Ludovic Bretin, Maarten N. van Ginkel, Wen Sun, Sylvestre Bonnet   +7 more
wiley   +1 more source

Lack of detectable HPV18 antibodies in 14% of quadrivalent vaccinees in a longitudinal cohort study

npj Vaccines
Although HPV vaccines are highly efficacious, a notable proportion of quadrivalent vaccinees are HPV18 seronegative post-vaccination. We have investigated this findings’ validity by comparing vaccine-induced antibody responses using two different ...
Penelope Gray, Filipe Colaço Mariz, Carina Eklund, Tiina Eriksson, Helena Faust, Hanna Kann, Martin Müller, Jorma Paavonen, Ville N. Pimenoff, Peter Sehr, Heljä-Marja Surcel, Joakim Dillner, Tim Waterboer, Matti Lehtinen   +13 more
doaj   +1 more source

Preventive Human Papilloma Virus Vaccine Guidelines for Clinical Use in China(2025 edition)

Xiehe Yixue Zazhi
Prophylactic human papilloma virus (HPV) vaccination is an effective strategy to prevent HPV infection and reduce the incidence of HPV-related diseases.Current clinical trials and real-world studies globally have demonstrated that prophylactic HPV ...
Society of Gynecologic Oncology, Chinese Medical Association, Branch of Colposcopy and Cervical Pathology, China Healthy Birth Science Association, Professional Committee on Cancer Prevention and Control, Chinese Preventive Medicine Association, Specialized Committee on Cervical Cancer Prevention and Control Research, China Maternal and Child Health Research Association, National Collaborative Group for Cervical Cancer Prevention and Treatment, China Cancer Foundation, Committee on Cervical Cancer, China Anti-Cancer Association, Branch of Obstetric and Gynecological Health Medicine, China International Exchange and Promotive Association for Medical and Health Care   +6 more
doaj   +1 more source

Cyclic Peptide–Polymer Conjugate Nanotubes for Delivery of SN‐38 in Treatment of Colorectal Cancer Model

Advanced Healthcare Materials, EarlyView.
This study develops cyclic peptidepolymer conjugate nanotubes with hydrophobic, drug‐rich cores to enhance drug loading and stability, and demonstrates their responsive disassembly, pharmacokinetics, and anti‐tumour efficacy in colorectal cancer models using the anticancer drug SN‐38.
Sophie K. Hill, Min Zeng, Santhosh Kalash Rajendrakumar, Robert Dallmann, Sébastien Perrier   +4 more
wiley   +1 more source

Shedding Light on the Cellular Uptake Mechanisms of Bioactive Glass Nanoparticles as Controlled Intracellular Delivery Platforms: A Review of the Recent Literature

Advanced Healthcare Materials, EarlyView.
This review summarizes the main uptake pathways of bioactive glass nanoparticles (BGNs) and their intracellular localization, highlighting that BGNs are mainly internalized and entrapped within endosomes/lysosomes. Strategies for controlled intracellular ion release, with implications for targeted modulation of cell behavior, are discussed. The need to
Andrada‐Ioana Damian‐Buda, Aldo R. Boccaccini   +1 more
wiley   +1 more source

Improve individual treatment by comparing treatment benefits: cancer artificial intelligence survival analysis system for cervical carcinoma [PDF]

, 2022
Jieyi Liang, Tingshan He, Hong Li, Xueqing Guo, Zhiqiao Zhang   +4 more
openalex   +1 more source

Enhancing Magnetic Hyperthermia at the Cell Membrane by Anchoring 92R‐Functionalized Magnetic Nanoparticles to Low‐Endocytic CCR9 Surface Receptors

Advanced Healthcare Materials, EarlyView.
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente, Isabel Corraliza‐Gorjón, Thomas S. van Zanten, María del Puerto Morales, Leonor Kremer, Domingo F. Barber   +5 more
wiley   +1 more source

Post-conization pathological upgrading and outcomes of 466 patients with low-grade cervical intraepithelial neoplasia

Frontiers in Oncology
IntroductionThe management of patients with low-grade cervical intraepithelial neoplasia (CIN1) remains controversial. We analyzed the pathological upgrading rates of patients with CIN1 undergoing conization, identifying influencing factors, and compared
Yulin Guo, Yulin Guo, Hongning Cai, Hongning Cai, Qiuzi Peng, Qiuzi Peng, Ying Wang, Ying Wang, Lu Li, Lu Li, Miao Zou, Miao Zou, Jinyue Guo, Jinyue Guo, Chaonan Wang, Chaonan Wang, Xufeng Wu, Xufeng Wu, Quanfu Ma, Quanfu Ma   +19 more
doaj   +1 more source

Hubungan Aktivitas Seksual pada Usia Dini, Promiskuitas dan Bilas Vagina dengan Kejadian Kanker Leher Rahim pada Pasien Onkology di RSUD Dr.moewardi Surakarta [PDF]

, 2011
Background: Cervical cancer ranks the top cause of cancer deaths in developing countries. At Dr. Moewardi Hospital Surakarta cervical cancer was found in most cancers.
Djannah, S. N. (Sitti), Ridhaningsih, R. (Ridhaningsih)   +1 more
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