Results 71 to 80 of about 718,452 (353)

Diagnostic performance of p16/Ki-67 dual immunostaining at different number of positive cells in cervical smears in women referred for colposcopy

Radiology and Oncology, 2021
The aim of the study was to evaluate the diagnostic accuracy of p16/Ki-67 dual immunostaining (p16/ Ki-67 DS) in cervical cytology and the number of positive p16/Ki-67 cells to diagnose high grade cervical intraepithelial neoplasia (CIN2+) in colposcopy ...
Gajsek Ursula Salobir, Dovnik Andraz, Takac Iztok, Ivanus Urska, Jerman Tine, Zatler Simona Sramek, Fokter Alenka Repse   +6 more
doaj   +1 more source

Exploring Iranian women’s perceptions and experiences regarding cervical cancer-preventive behaviors [PDF]

, 2018
Background Preventive behaviors regarding cervical cancer are essential for women’s health. Even though many studies have addressed women’s knowledge and attitudes toward cervical cancer, little information is available about their experiences of ...
Jafari, Fatemeh, Khazaee-Pool, Maryam, Ponnet, Koen, Yargholi, Fatemeh   +3 more
core   +3 more sources

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Concomitant human papillomavirus (HPV) vaccination and screening for elimination of HPV and cervical cancer

Nature Communications
HPV vaccination with concomitant HPV-based screening of young women has been proposed for faster cervical cancer elimination. We describe the baseline results of a population-based trial of this strategy to reduce the incidence of HPV.
Laila Sara Arroyo Mühr, Andrea Gini, Emel Yilmaz, Sadaf S. Hassan, Camilla Lagheden, Emilie Hultin, Ainhoa Garcia Serrano, Agustin E. Ure, Helena Andersson, Roxana Merino, K. Miriam Elfström, Iacopo Baussano, Joakim Dillner   +12 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Cervical precancer screening using self-sampling, HPV DNA testing, and mobile colposcopy in a hard-to-reach community in Ghana: a pilot study

BMC Cancer
Background The World Health Organization has set ambitious goals to eliminate cervical cancer, necessitating evidence on increasing coverage and access to screening and treatment in high-burden areas.
Kofi Effah, Ethel Tekpor, Comfort Mawusi Wormenor, John Allotey, Yaa Owusu–Agyeman, Seyram Kemawor, Dominic Agyiri, Johnpaul Amenu, Jonathan M. Gmanyami, Martin Adjuik, Kwabena Obeng Duedu, Joyce B. Der, Nana Owusu Mensah Essel, Margaret Kweku   +13 more
doaj   +1 more source

Evidence from Outcomes: Gender-Neutral 2vHPV Vaccination at Moderate Coverage Drives Rapid Depletion of HPV16/18 Among Vaccinated and Unvaccinated Women

Viruses
Human papillomavirus (HPV) vaccination may eventually eradicate oncogenic vaccine-targeted HPVs but only with a strategy that also protects unvaccinated individuals.
Matti Lehtinen, Ville N. Pimenoff, Tiina Eriksson, Camilla Lagheden, Anna Söderlund-Strand, Heljä-Marja Surcel, Joakim Dillner   +6 more
doaj   +1 more source

Cervical Cancer Screening Among Reproductive-aged Women: a Crossectional Survey in Tabanan Regency [PDF]

, 2017
Background and purpose: Cervical and breast cancers are the most common Malignancies among women in Indonesia. The prevalence of cervical cancer in Bali was 0.6% in 2013.
Karmaya, M. (Mangku), Suariyani, N. L. (N), Yenny Apriani, Desak Gede   +2 more
core   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source