Results 21 to 30 of about 9,501 (200)
Isolated focal dystonia phenotypes are associated with distinct patterns of altered microstructure
NeuroImage: Clinical, 2018 Objective: Isolated adult-onset focal dystonia is considered a network disorder with disturbances to the motor basal ganglia and cerebellar circuits playing a pathophysiological role, but why specific body regions become affected remains unknown.
Brian D. Berman +4 more
doaj +1 more source
Medicina, 2022 Background: Cervical dystonia is a highly disabling hyperkinetic movement disorder with a lot of nonmotor symptoms. One symptom with a high prevalence is depression, which may negatively affect dystonia patients.
Vlada Meļņikova +3 more
doaj +1 more source
Evaluation of outcome of different neurosurgical modalities in management of cervical dystonia
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2022 Background Cervical dystonia is the most common form of focal dystonia and is managed by multiple modalities including repeated botulinum toxin injections, in addition to medical treatment with anticholinergics, muscle relaxants, and physiotherapy ...
Mazen Alkarras +6 more
doaj +1 more source
Multimodal Quantitative MRI Reveals No Evidence for Tissue Pathology in Idiopathic Cervical Dystonia
Frontiers in Neurology, 2019 Background: While in symptomatic forms of dystonia cerebral pathology is by definition present, it is unclear so far whether disease is associated with microstructural cerebral changes in idiopathic dystonia.
René-Maxime Gracien +14 more
doaj +1 more source
Smoothness of movement in idiopathic cervical dystonia
Scientific Reports, 2022 Smoothness (i.e. non-intermittency) of movement is a clinically important property of the voluntary movement with accuracy and proper speed. Resting head position and head voluntary movements are impaired in cervical dystonia.
Antonio Caronni +10 more
doaj +1 more source
CHEMODNERVATION FOR CERVICAL DYSTONIA: A CLINICAL REVIEW
Khyber Medical University Journal, 2020 Cervical dystonia (CD) is a focal dystonia characterized by involuntary contractions of neck muscles that result in patterned movements and abnormal postures of the head and neck that have a directional quality.
Muhammad Atif Ameer, Danish Bhatti
doaj +1 more source
Cervical dystonia: a disorder of the midbrain network for covert attentional orienting.
Frontiers in Neurology, 2014 While the pathogenesis of cervical dystonia remains unknown, recent animal and clinical experimental studies have indicated its probable mechanisms. Abnormal temporal discrimination is a mediational endophenotype of cervical dystonia and informs new ...
Michael eHutchinson +18 more
doaj +1 more source
The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia
Advanced Science, EarlyView.The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo +3 more
wiley +1 more source
Frontiers in Neurology, 2017 Abnormalities in the somatosensory system are increasingly being recognized in patients with dystonia. The aim of this study was to investigate whether sensory abnormalities are confined to the dystonic body segments or whether there is a wider ...
Lejla Paracka +10 more
doaj +1 more source
Probabilistic Lesion Mapping to Optimize Thalamotomy Targets for Focal Hand Dystonia
Annals of Neurology, EarlyView.Objective Focal hand dystonia (FHD) severely impairs task‐specific motor control, yet the optimal surgical target for stereotactic intervention remains uncertain. This study aimed to identify the precise thalamic lesion site associated with symptomatic improvement and to clarify its network connectivity. Methods We retrospectively analyzed 164 patients
Masahiko Nishitani +12 more
wiley +1 more source