Results 41 to 50 of about 9,501 (200)

Cervical Dystonia Is Associated With Aberrant Inhibitory Signaling Within the Thalamus

Frontiers in Neurology, 2021
Objective: The objective of this study is to investigate whether alterations in the neurotransmission of gamma-aminobutyric acid (GABA) in the thalamus are present in patients with cervical dystonia compared to healthy controls.Methods: GABA magnetic ...
Christopher L. Groth, Christopher L. Groth, Mark Brown, Justin M. Honce, Erika Shelton, Stefan H. Sillau, Brian D. Berman, Brian D. Berman, Brian D. Berman   +8 more
doaj   +1 more source

Trust the Patient Not the Doctor: The Determinants of Quality of Life in Cervical Dystonia

Frontiers in Neurology, 2020
Background: Mood disorder is common in cervical dystonia and can impact on quality of life. It often precedes the onset of cervical dystonia and does not improve with botulinum toxin therapy.Objective: To assess health-related quality of life in relation
Ihedinachi Ndukwe, Ihedinachi Ndukwe, Sean O'Riordan, Cathal B. Walsh, Michael Hutchinson, Michael Hutchinson   +5 more
doaj   +1 more source

Movement Disorders in Neuromyelitis Optica Spectrum Disorder: A Systematic Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Several movement disorders (MD) have been reported to occur in neuromyelitis optica spectrum disorder (NMOSD). No extensive review has addressed the whole spectrum of MD in NMOSD. Objective This article aims to review MD in NMOSD, describing its prevalence and features.
Luciana A.F. Bringel, Pedro L.G.S.B. Lima, Pedro V.F. Rodrigues, Francisco L.H.B. Cavalcante, Amanda R. Pinheiro, Fabricia M.S. Saraiva, Cynthia P. Rodrigues, Paulo V.S. Gonçalves, Leonardo J.R.A. Melo, Antônio E. Camelo‐Filho, Avelino M. Dutra‐Junior, Samuel R.O. Veras, Fernanda M.M. Carvalho, Flávia P.S. Rolim, Gabriela J. Martins, José A.C. D'Almeida, Pedro Braga‐Neto, Milena S. Pitombeira, Paulo R. Nobrega   +18 more
wiley   +1 more source

Managing Dystonia in Partington Syndrome

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Bilateral focal hand dystonia is an almost pathognomonic sign of Partington syndrome, frequently accompanied by intellectual disability and oromotor dyspraxia. However, a few studies have focused on the treatment of this focal dystonia, making patient management uncertain.
Emilie Pichon, Aurea Alioth, Sabina Catalano Chiuvé, André Zacharia, Marta Ruiz‐Lopez, David P. Breen, Florence Zangas‐Gehri, Florent Draye, Aurore Curie, Duncan Wilson, Victor S.C. Fung, Stephen Duma, Joël Fluss, Julien F. Bally   +13 more
wiley   +1 more source

Anticholinergic Burden and Botulinum Toxin Needs after Deep Brain Stimulation in Adult and Pediatric Patients with Dystonia

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Anticholinergic medications and botulinum neurotoxin injections are established treatments for dystonia, yet they carry potential side effects and practical challenges. Deep brain stimulation (DBS) is offered in case of poor response to these approaches.
Marcela A. Montiel, Alessandro Magliozzi, Wei Kang Lim, Carolina Gorodetsky, George M. Ibrahim, Alfonso Fasano   +5 more
wiley   +1 more source

The Mechanisms of Movement Control and Time Estimation in Cervical Dystonia Patients

Neural Plasticity, 2013
Traditionally, the pathophysiology of cervical dystonia has been regarded mainly in relation to neurochemical abnormities in the basal ganglia. Recently, however, substantial evidence has emerged for cerebellar involvement.
Pavel Filip, Ovidiu V. Lungu, Daniel J. Shaw, Tomas Kasparek, Martin Bareš   +4 more
doaj   +1 more source

Segmental and Multifocal Isolated Dystonias: Similarities and Differences

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Whether the traditional distinction between segmental and multifocal dystonia is clinically or scientifically useful remains unclear. Objective To evaluate whether idiopathic isolated adult‐onset segmental and multifocal dystonia can be differentiated based on clinical features other than the contiguity of affected body regions ...
Hyder A. Jinnah, Vittorio Velucci, Daniele Belvisi, Gamze Kilic‐Berkmen, Joel S. Perlmutter, Laura J. Wright, Christine Klein, Jeanne S. Feuerstein, Steven Bellows, Joseph Jankovic, Cynthia Comella, Richard L. Barbano, Aparna Wagle Shukla, Stephen G. Reich, Mark S. LeDoux, Alberto J. Espay, Kevin R. Duque, Florence C.F. Chang, Victor S.C. Fung, Sarah Pirio‐Richardson, Carmen Terranova, Emile S. Moukheiber, Sarah Idrissi, Barbara Vitucci, Susan H. Fox, Samuel Frank, Natividad Stover, Brian D. Berman, Rachel Saunders‐Pullman, William G. Ondo, Christopher L. Groth, Marcello Esposito, Laura Avanzino, Francesco Bono, Roberto Erro, Marcello Mario Mascia, Antonella Muroni, Alfredo Berardelli, Giovanni Defazio   +38 more
wiley   +1 more source

Investigating Sleep Concerns in Cervical Dystonia

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Heterogenous, small cohorts, and co‐occurrence of pain and psychiatric burden complicate understanding of sleep in dystonia. Objective To investigate sleep concerns in cervical dystonia (CD). Methods Longitudinal data from CD‐PROBE on subjects who were toxin‐naïve, new to practice, or without injections for at least 16 weeks were ...
Abhimanyu Mahajan, David Andrés González, Cynthia Comella   +2 more
wiley   +1 more source

The role of pallidum in the neural integrator model of cervical dystonia

Neurobiology of Disease, 2019
Dystonia is the third most common movement disorder affecting three million people worldwide. Cervical dystonia is the most common form of dystonia. Despite common prevalence the pathophysiology of cervical dystonia is unclear.
Alexey Sedov, Svetlana Usova, Ulia Semenova, Anna Gamaleya, Alexey Tomskiy, J. Douglas Crawford, Brian Corneil, H.A. Jinnah, Aasef G. Shaikh   +8 more
doaj   +1 more source

Dystonia Scales for Children: Challenges and Obstacles in DBS Practice

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Dystonia in pediatric patients often coexists with other movement disorders and neurodevelopmental issues. Current rating scales for evaluating pediatric deep brain stimulation (DBS) candidates are not universally applicable and often require a non‐validated combination of the existing scales.
Marcela Montiel, Carolina Gorodetsky, Laura Cif, Nardo Nardocci, Alfonso Fasano   +4 more
wiley   +1 more source