Results 71 to 80 of about 2,422,171 (245)

[Health promotion strategy 2004] / Irish Cervical Screening Programme

, 2004
Irish Cervical Screening ...
Irish Cervical Screening Programme (ICSP)
core  

Inequalities in the incidence of cervical cancer in South East England 2001-2005: an investigation of population risk factors. [PDF]

, 2009
BACKGROUND: The incidence of cervical cancer varies dramatically, both globally and within individual countries. The age-standardised incidence of cervical cancer was compared across primary care trusts (PCTs) in South East England, taking into account ...
Jack, Ruth H, Jack Ruth H, Currin, Laura G, Elizabeth A Davies, Jack, Ruth H., Davies, Elizabeth A.; id_orcid, Henrik Møller, Mak, Vivian, Karen M Linklater, Møller Henrik, Møller, Henrik, Vivian Mak, Linklater, Karen M., Currin, Laura G., Mak Vivian, Moller, Henrik; id_orcid, Linklater, Karen M, Linklater Karen M, Ruth H Jack, Davies Elizabeth A, Laura G Currin, Davies, Elizabeth A, Currin Laura G   +22 more
core   +2 more sources

Cervico-mandibular muscle activity in females with chronic cervical pain a descriptive, cross-sectional, correctional study [PDF]

, 2012
Includes abstract.Includes bibliographical references.Chronic musculoskeletal conditions of the spine and periphery are a burden both internationally and in South Africa.
Lang, Patricia
core   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

HPV types and cofactors causing cervical cancer in Peru. [PDF]

, 2001
We conducted a hospital-based case-control study in Peru of 198 women with histologically confirmed cervical cancer (173 squamous cell carcinomas and 25 cases of adenocarcinoma/adenosquamous carcinoma) and 196 control women.
Muñoz, N, J Walboomers, I Guerrero, E Caceres, Santos, C, Galdos, O, Castillo, M, Walboomers, J, S Klug, Caceres, E, C Velarde, M Almonte, Klug, S, O Galdos, Alvarez, M, N Muñoz, Meijer, C, C Santos, M Alvarez, Guerrero, I, C Meijer, Almonte, M, M Castillo, Velarde, C   +23 more
core   +1 more source

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

Advanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li, Ka Man Ng, Xingsheng Shu, Xiaoxue Chai, Kai Yau Wong, Gopesh Srivastava, Anthony T.C. Chan, Wai Yee Chan, Qian Tao   +8 more
wiley   +1 more source

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng, Mengmeng Wang, Kang Wang, Zhuo Xing, Yulong Hong, Tongtong Li, Geng Zong, Chong Yang, Dan Zhang, Zhangling Chen, Xin Jin   +10 more
wiley   +1 more source

Mechanical Flexibility Enables DNA Origami to Overcome Steric Confinement in Mucus

Advanced Science, EarlyView.
Mechanical flexibility is introduced as a design parameter to enhance nanocarrier transport in mucus. Using DNA origami, flexibility is decoupled from size, shap and surface chemistry, revealing improved passage through confined hydrogel networks. While surface passivation reduces aggregation, flexibility further boosts transport, offering a general ...
Matteo Tollemeto, Emily Tsang, Marie Karen Tracy Hong Lin, Luca Mannino, Kurt V. Gothelf, Anja Boisen   +5 more
wiley   +1 more source

TET1 Inhibition Promotes Therapeutic Sensitivity in TP53‐Mutant GBM by Influencing Genome Fragility and Altering TAMs Biology

Advanced Science, EarlyView.
In TP53mut GBM cells, reduced P53 function is associated with increased TET1 expression. Genetic or pharmacological inhibition of TET1 correlates with genome fragility, including DNA damage, cellular senescence, telomere shortening, and reactive oxygen species accumulation, which may contribute to increased efficacy of antitumor therapy.
Zhuonan Pu, Jinqiu Liu, Yuxuan Deng, Shuyu Hao, Xiaoli Zhang, Mingxu Yang, Chao Guo, Chao Du, Yingdan Chen, Tai Sun, Nan Ji, Zhengping Zhuang, Jie Feng   +12 more
wiley   +1 more source

A new type of papillomavirus DNA, its presence in genital cancer biopsies and in cell lines derived from cervical cancer [PDF]

, 1984
DNA of a new papillomavirus type was cloned from a cervical carcinoma biopsy. Two EcoRI clones of 7.8 and 6.9 kb in length were obtained, the latter contained a 900-bp deletion. The BamHI fragments of both clones were used to characterize the DNA.
Boshart, Michael, Gissmann, Lutz, Kleinheinz, Andreas, Ikenberg, Hans, Hausen, Harald zur, Scheurlen, Wolfram   +5 more
core   +1 more source