Results 61 to 70 of about 359,306 (210)

Barriers and facilitators of follow-up among women with precancerous lesions of the cervix in Cameroon: a qualitative pilot study

International Journal of Women's Health, 2019
Simon Manga,1,2 Edith Kiyang,1 Rosanna F DeMarco2 1Women’s Health Program, Cameroon Baptist Convention Health Services, Bamenda, Cameroon; 2College of Nursing and Health Sciences, University of Massachusetts Boston, Boston, MA, USA Purpose: This ...
Manga S, Kiyang E, DeMarco RF
doaj  

Towards the global elimination of cervical cancer

Papillomavirus Research, 2019
Two very effective prevention strategies for cervical cancer exist – vaccination against the human papillomavirus (HPV) and cervical screening with primary HPV testing followed by treatment of precancerous lesions.
Karen Canfell
doaj   +1 more source

Follow‐Up and Outcomes After Thermal Ablation Treatment Among HIV‐Infected Women From Resource‐Limited Countries With Positive HPV‐Based Screening: Results of the AIMA‐CC Cohort (ANRS 12375)

International Journal of Cancer, Volume 159, Issue 12, Page 3016-3028, 15 December 2026.
ABSTRACT Primary screening for human papillomavirus (HPV) followed by treatment with thermal ablation (TA) is an important component of the global strategy to eliminate cervical cancer. However, evidence on post‐TA outcomes in women living with HIV (WLWH) remains limited.
Pierre Debeaudrap, Firmin Nongodo Kabore, Limsreng Setha, Joseph Tegbe, Brahima Doukoure, Moeung Sotheara, Olivier Segeral, Korn Aun, Eugène Messou, Matthieu Chicaud, Kim Sothea, Pierre Vassilakos, Armel Poda, Evelyne Kasilé Poda, Antoine Jaquet, Adolphe Some, Patrick Petignat, Gary Clifford, Apollinaire Horo   +18 more
wiley   +1 more source

Impact of telephone reminders on posttreatment follow-up among women treated for cervical precancers in Cameroon: A randomized controlled trial

Gynecologic Oncology Reports
Background: Effective management of cervical precancerous lesions requires appropriate posttreatment follow-up. In Cameroon like in many Low-and-Middle-Income Countries (LMICs), most women treated for cervical precancers do not present for posttreatment ...
Joseph F. Nkfusai, Simon M. Manga, Kathleen Nulah, Calvin Ngalla, Claude Ngwayu, Charlotte B. Mbuwir, Nicholas Tendongfor, Edie Gregory Halle Ekane, Joël Fokom Domgue   +8 more
doaj   +1 more source

Designing low-cost, accurate cervical screening strategies that take into account COVID-19: a role for self-sampled HPV typing2

Infectious Agents and Cancer, 2020
Background We propose an economical cervical screening research and implementation strategy designed to take into account the typically slow natural history of cervical cancer and the severe but hopefully temporary impact of COVID-19.
Kayode Olusegun Ajenifuja, Jerome Belinson, Andrew Goldstein, Kanan T. Desai, Silvia de Sanjose, Mark Schiffman   +5 more
doaj   +1 more source

Productive or Transforming? How Epithelial Compartmentalization of HPV DNA and E6/E7 Transcripts Shapes Cervical Screening Assay Performance

Journal of Medical Virology, Volume 98, Issue 11, November 2026.
ABSTRACT The human papillomavirus (HPV) life cycle is linked to epithelial cell differentiation, with viral genome amplification, E6/E7 transcription, and virion assembly spatially compartmentalized within the cervical epithelium. This organization is disrupted in transforming lesions.
Konstanze Schichl, John Doorbar
wiley   +1 more source

Resource‐Adapted Triage Strategies for Women Testing HPV Positive With Self‐Collected Vaginal Samples in Cameroon

International Journal of Cancer, Volume 159, Issue 8, Page 1949-1961, 15 October 2026.
Although human papillomavirus (HPV) testing is recommended for cervical cancer screening in low‐ and middle‐income countries, optimal management of HPV‐positive women remains undetermined, particularly in resource‐limited settings. Here, using data from the 3T study involving women in Cameroon, the authors evaluated the ability of extended HPV ...
Micol Murtas, Pierre Vassilakos, Ania Wisniak, Ketty Hu, Marc Arbyn, Gilles W. Tankeu Happi, Esther Abatsong, François Marcel Ndam Nsangou, Jean‐Christophe Tille, Essia Saiji, Bruno Kenfack, Patrick Petignat   +11 more
wiley   +1 more source

Spatiotemporally deciphering the mysterious mechanism of persistent HPV‐induced malignant transition and immune remodelling from HPV‐infected normal cervix, precancer to cervical cancer: Integrating single‐cell RNA‐sequencing and spatial transcriptome

Clinical and Translational Medicine, 2023
Background The mechanism underlying cervical carcinogenesis that is mediated by persistent human papillomavirus (HPV) infection remains elusive. Aims Here, for the first time, we deciphered both the temporal transition and spatial distribution of ...
Chenyan Guo, Xinyu Qu, Xiaoyan Tang, Yu Song, Jue Wang, Keqin Hua, Junjun Qiu   +6 more
doaj   +1 more source

HPV Testing Versus Cytology for Cervical Cancer Screening Among Women 50 Years and Older: Evidence From the HPV FOCAL Randomized Controlled Trial

International Journal of Cancer, Volume 159, Issue 8, Page 2066-2074, 15 October 2026.
ABSTRACT Evidence on the comparative effectiveness of HPV testing versus cytology specifically in women aged ≥ 50 years who are approaching screening cessation remains limited. This analysis included 6471 women aged ≥ 50 at baseline screening in the HPV FOCAL randomized clinical trial. Women were randomly allocated to receive cytology (Control Group, n 
Md Saiful Alam, Laurie W. Smith, Lovedeep Gondara, Darrel Cook, Ruth Elwood Martin, Stuart Peacock, Lily Proctor, Gavin Stuart, David Patrick, Eduardo L. Franco, Mel Krajden, Anna Gottschlich, Gina S. Ogilvie   +12 more
wiley   +1 more source

Exploring Vitamin D Metabolism in Gynaecological Malignancies: Redox‐Dependent and Redox‐Independent Anticancer Mechanisms From Preclinical Models to Clinical Evidence

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Gynaecological malignancies account for over 1.4 million new diagnoses, with outcomes constrained by late‐stage presentation and chemoresistance. Dysregulated redox homeostasis is a hallmark of tumourigenesis. Tumour cells maintain elevated basal reactive oxygen species (ROS), which support proliferative signalling but may also increase ...
Hoi Ching Cherry Chan, Sachin Bhoora, Esther Zhou, Sumari Marais, Rivak Punchoo   +4 more
wiley   +1 more source