Results 111 to 120 of about 569,540 (328)

A novel misoprostol delivery system for induction of labor: clinical utility and patient considerations

open access: yesDrug Design, Development and Therapy, 2015
Megan L Stephenson, Deborah A WingDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of California, Irvine Medical Center, Orange, CA, USAAbstract: Induction of labor is one of the most commonly performed ...
Stephenson ML, Wing DA
doaj  

Cytokine mRNA Delivery and Local Immunomodulation in the Placenta Using Lipid Nanoparticles

open access: yesAdvanced Therapeutics, EarlyView.
This article evaluates lipid nanoparticles to deliver immunomodulatory mRNA to placental cells and mouse placentas to study and treat the immune underpinnings of placenta‐related diseases. Lipid nanoparticles induce cytokine secretion and macrophage polarization toward an anti‐inflammatory state.
Samuel I. Hofbauer   +9 more
wiley   +1 more source

RONIN/HCF1‐TFEB Axis Protects Against D‐Galactose‐Induced Cochlear Hair Cell Senescence Through Autophagy Activation

open access: yesAdvanced Science, EarlyView.
D‐galactose (D‐gal) induced inner ear hair cell senescence by inhibiting TFEB transcription. RONIN/HCF1 promotes TFEB transcription to prevent cochlear HCs from D‐gal‐induced senescence through autophagy activation. Abstract Age‐related hearing loss is characterized by senescent inner ear hair cells (HCs) and reduced autophagy.
Yongjie Wei   +18 more
wiley   +1 more source

Cervical ripening methods for labor induction [PDF]

open access: diamond, 2004
Fernanda Garanhani Surita   +4 more
openalex   +1 more source

Elevated Histone Lactylation Mediates Ferroptosis Resistance in Endometriosis Through the METTL3‐Regulated HIF1A/HMOX1 Signaling Pathway

open access: yesAdvanced Science, EarlyView.
This study reveals that histone lactylation, a modification derived from lactate, plays a crucial role in ferroptosis resistance in ectopic endometrial stromal cells. This resistance is mediated via the HIF1A/HMOX1 pathway regulated by METTL3. In vivo, a combination of 2‐DG and erastin shows promise as an effective treatment for endometriosis ...
Zongwen Liang   +8 more
wiley   +1 more source

Preinduction cervical ripening with prostaglandin E2: influence on psychomotor evolution in the first year

open access: bronze, 1984
C. Van Pelt   +6 more
openalex   +1 more source

NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea

open access: yesAdvanced Science, EarlyView.
This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy