Results 241 to 250 of about 569,540 (328)

Enhancing Spinal Metastasis Detection and Feature Evaluation on Computed Tomography Scans Using Deep‐Learning Systems

open access: yesAdvanced Intelligent Systems, EarlyView.
A deep‐learning system (DLS) is developed for the automatic detection of spinal metastases and the evaluation of associated features using computed tomography imaging. A multireader, multicase analysis and a prospective multicenter cohort study are conducted to evaluate the diagnostic performance.
Zhiyu Wang   +16 more
wiley   +1 more source

Empowering Biomedical Research with Foundation Models in Computational Microscopy: A Systematic Review

open access: yesAdvanced Intelligent Systems, EarlyView.
The integration of foundation models into computational microscopy revolutionizes biomedical research by enhancing imaging resolution, accelerating data analysis, and enabling real‐time biological interpretation. This systematic review critically examines recent advancements, highlights translational challenges, and discusses the transformative ...
Di Ding   +5 more
wiley   +1 more source

Clinlabomics‐Enabled Blending Ensemble Learning for Low‐Cost Pan‐Cancer Detection and Classification Using Routine Clinical Laboratory Data

open access: yesAdvanced Intelligent Systems, EarlyView.
Researchers develop clinlabomics assisted for cancer identification, an artificial intelligence‐powered system using routine clinical lab data to detect and identify 10 cancer types. Tested on 19 199 individuals, it achieves 90.39% sensitivity and 82.41% specificity in cancer detection, with 72.57% accuracy in identifying specific cancer types ...
Bowen Zhang   +9 more
wiley   +1 more source

Mycosis Fungoides, Sézary Syndrome, and Cutaneous B‐Cell Lymphomas: 2025 Update on Diagnosis, Risk‐Stratification, and Management

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Disease Overview Primary cutaneous lymphomas are a rare and heterogeneous group of extranodal lymphomas that require the integration of clinical and histopathologic data for classification and treatment. Diagnosis Diagnosis and disease classification is based on histopathologic review and immunohistochemical staining of an appropriate skin ...
Alexandra C. Hristov   +2 more
wiley   +1 more source

Association Between Moraxella catarrhalis and Nodular Lymphocyte‐Predominant Hodgkin Lymphoma

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Nodular lymphocyte‐predominant Hodgkin Lymphoma (NLPHL) may be an antigen‐driven malignancy. Recent studies demonstrated that in NLPHL patients, lymphoma B‐cell receptor can bind proteins derived from Moraxella catarrhalis (MC) and Rothia mucilaginosa (RM). We examined whether MC and RM can be detected in NLPHL lymph nodes.
Izidore S. Lossos   +7 more
wiley   +1 more source

Perspectives on the Current and Future State of Artificial Intelligence in Medical Genetics

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Artificial intelligence (AI) is rapidly transforming numerous aspects of daily life, including clinical practice and biomedical research. In light of this rapid transformation, and in the context of medical genetics, we assembled a group of leaders in the field to respond to the question about how AI is affecting, and especially how AI will ...
Benjamin D. Solomon   +20 more
wiley   +1 more source

Survivorship of Individuals With Double Heterozygosity for Achondroplasia and Type 2 Collagenopathy

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Historically, double heterozygosity, or a diagnosis of two separate, dominant genetic conditions, was often thought to be lethal in individuals with autosomal dominant skeletal dysplasias. In previously published studies of individuals with dual dysplasia diagnoses of achondroplasia and type 2 collagenopathy, infants died of respiratory ...
Valerie R. Schwartz   +3 more
wiley   +1 more source

Artificial Intelligence Software Changes Rare Disease Testing Strategy in Real Time: An International Case Series Using Face2Gene

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Genetic disorders commonly share features such as developmental delays, cognitive impairment, and behavioral challenges, yet many conditions also present unique dysmorphic features that distinguish them. Performing a thorough medical and family history and a detailed physical exam with attention to dysmorphic features is often the first step ...
Natasha L. Rudy   +15 more
wiley   +1 more source

Extent of Resection and Role of Adjuvant Radiotherapy in Olfactory Neuroblastoma Without Definite Radiologic Evidence of Dural Invasion

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Objectives To evaluate the impact of the extent of resection and adjuvant radiotherapy (RT) on treatment outcomes in patients with early‐stage olfactory neuroblastoma (ONB) without definite dural invasion. Methods A retrospective review of ONB cases from two centers within a single institution between 1992 and 2023 was performed ...
Tae‐Bin Won   +8 more
wiley   +1 more source

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