Results 51 to 60 of about 1,494,574 (301)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Clients' returning for cervical screening results : a focus group study exploring the reasons why women spontaneously return for their results at the Khayelitsha Cervical Cancer Screening Project [PDF]

, 2004
Bibliography: leaves 112-123.Cervical cancer is integrally associated with the problems of poverty in the developing world. It is the most common cancer cause of death among women in these regions.
Honikman, Simone
core   +1 more source

Human papillomavirus-based cervical screening and long-term cervical cancer risk: a randomised health-care policy trial in Sweden

The Lancet Public Health
Summary: Background: Human papillomavirus (HPV)-based cervical screening is a globally recommended public health policy. Randomised clinical trials find superior performance of primary HPV-based screening compared with cytology for preventing cervical ...
Jiangrong Wang, PhD, K Miriam Elfström, PhD, Joakim Dillner, ProfMD   +2 more
doaj   +1 more source

Cervical screening in Australia 2010-2011 [PDF]

, 2013
This paper presents the latest national statistics monitoring the National Cervical Screening Program, which aims to reduce incidence, morbidity and mortality from cervical cancer.Summary:The National Cervical Screening Program (NCSP) aims to reduce

core  

MAVARIC - a comparison of automation-assisted and manual cervical screening: a randomised controlled trial. [PDF]

, 2011
OBJECTIVES: The principal objective was to compare automation-assisted reading of cervical cytology with manual reading using the histological end point of cervical intraepithelial neoplasia grade II (CIN2) or worse (CIN2+). Secondary objectives included
G Dunn, S Moss, MAVARIC Trial Study Group, R Blanks, Sadique, A, Sadique, Z, Kitchener, HC, Dunn, G, A Gray, Moss, S, M Desai, Cubie, H, Blanks, R, R Legood, Legood, R, Desai, M, H Cubie, Desia, M, Z Sadique, Gray, A, HC Kitchener   +20 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Randomised trial of HPV self-sampling among non-attenders in the Slovenian cervical screening programme ZORA: comparing three different screening approaches

Radiology and Oncology, 2018
To overcome obstacles within the Slovenian organised cervical cancer screening programme, a randomised pilot study of human papillomavirus (HPV) self-sampling among non-attenders was performed, aiming to assess three different screening approaches.
Ivanus Urska, Jerman Tine, Fokter Alenka Repse, Takac Iztok, Prevodnik Veronika Kloboves, Marcec Mateja, Gajsek Ursula Salobir, Pakiz Maja, Koren Jakob, Celik Simona Hutter, Kramberger Kristina Gornik, Klopcic Ulrika, Kavalar Rajko, Zatler Simona Sramek, Kuzmanov Biljana Grcar, Florjancic Mojca, Nolde Natasa, Novakovic Srdjan, Poljak Mario, Zakelj Maja Primic   +19 more
doaj   +1 more source

Cervical screening in Australia 2011-2012 [PDF]

, 2014
This report presents the latest national statistics monitoring the National Cervical Screening Program, which aims to reduce incidence, morbidity and mortality from cervical cancer.

core  

Inequalities in the incidence of cervical cancer in South East England 2001-2005: an investigation of population risk factors. [PDF]

, 2009
BACKGROUND: The incidence of cervical cancer varies dramatically, both globally and within individual countries. The age-standardised incidence of cervical cancer was compared across primary care trusts (PCTs) in South East England, taking into account ...
Jack, Ruth H, Jack Ruth H, Currin, Laura G, Elizabeth A Davies, Jack, Ruth H., Davies, Elizabeth A.; id_orcid, Henrik Møller, Mak, Vivian, Karen M Linklater, Møller Henrik, Møller, Henrik, Vivian Mak, Linklater, Karen M., Currin, Laura G., Mak Vivian, Moller, Henrik; id_orcid, Linklater, Karen M, Linklater Karen M, Ruth H Jack, Davies Elizabeth A, Laura G Currin, Davies, Elizabeth A, Currin Laura G   +22 more
core   +2 more sources

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source