Results 71 to 80 of about 1,494,574 (301)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

A cross-sectional study of the prevalence, barriers, and facilitators of cervical cancer screening in family planning clinics in Mombasa County, Kenya

BMC Health Services Research, 2022
Background Cervical cancer is the most common cancer in sub-Saharan Africa. With appropriate screening and treatment, cervical cancer can be prevented.
McKenna C. Eastment, George Wanje, Barbra A. Richardson, Emily Mwaringa, Shem Patta, Kenneth Sherr, Ruanne V. Barnabas, Kishorchandra Mandaliya, Walter Jaoko, R. Scott McClelland   +9 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Impact of differentiating between persistent and new infections on colposcopy referral in HPV-positive triage-negative women: results from the NTCC2 study

Infectious Agents and Cancer
Background In cervical screening, human papillomavirus (HPV)-positive women at 1-year retesting are typically referred to colposcopy. This study, by the use of extended genotyping, estimates the impact of distinguishing persistent from new infections in ...
Annarosa Del Mistro, Pamela Mancuso, Francesca Carozzi, Laura De Marco, Simonetta Bisanzi, Giampaolo Pompeo, Guglielmo Ronco, Silvia Gori, Elena Allia, Daniela Gustinucci, Helena Frayle, Anna Iossa, Elena Cesarini, Simonetta Bulletti, Basilio Passamonti, Jessica Viti, Laura Toniolo, Francesco Venturelli, Paolo Giorgi Rossi, Maria Benevolo, the NTCC2 Working Group   +20 more
doaj   +1 more source

Cervical Screening Performance [PDF]

American Journal of Clinical Pathology, 2021
Mark Schiffman, Nicolas Wentzensen
openaire   +2 more sources

Cervical cancer screening programs in Latin America and the Caribbean. [PDF]

, 2008
Latin America and the Caribbean (LAC) have a significant burden of cervical cancer. Prophylactic human papillomavirus (HPV) vaccines are an opportunity for primary prevention and new screening methods, such as new HPV DNA testing, are promising ...
Gamboa, Oscar A, Pereira, Ana, Almonte, Maribel, Ferrer, Elena, Jerónimo, José, Murillo, Raul, Pereira Scalabrino, Ana, Lazcano Ponce, Eduardo, Gamboa, Oscar A., Lazcano-Ponce, Eduardo   +9 more
core   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Cervical Cancer Screening [PDF]

Journal of the National Comprehensive Cancer Network, 2010
These NCCN Guidelines Insights focus on recent recommendations for cervical cancer screening and management of abnormal screening tests. When the NCCN Panel convened to update the NCCN Guidelines for Cervical Cancer Screening, they decided to adopt and endorse guidelines from other organizations to avoid duplication of effort.
Edward E, Partridge, Nadeem R, Abu-Rustum, Susan M, Campos, Patrick J, Fahey, Michael, Farmer, Rochelle L, Garcia, Anna, Giuliano, Howard W, Jones, Subodh M, Lele, Richard W, Lieberman, Stewart L, Massad, Mark A, Morgan, R Kevin, Reynolds, Helen E, Rhodes, Diljeet K, Singh, Karen, Smith-McCune, Nelson, Teng, Cornelia Liu, Trimble, Fidel, Valea, Sharon, Wilczynski   +19 more
openaire   +2 more sources

Associations Between Methylation of Paternally Expressed Gene 3 (PEG3), Cervical Intraepithelial Neoplasia and Invasive Cervical Cancer. [PDF]

, 2013
Cytology-based screening for invasive cervical cancer (ICC) lacks sensitivity and specificity to discriminate between cervical intraepithelial neoplasia (CIN) likely to persist or progress from cases likely to resolve.
Bartlett, John A., Britta Swai, Smith Jennifer S., Obure, Joseph, Obure Joseph, Vasquez, Brandi, Nye, Monica D., Swai, Britta, Gammon, Marilie D, Hoyo Cathrine, Frances Wang, Vasquez Brandi, Zhiqing Huang, Oneko Olola, Overcash, Francine, Oneko, Olola, Vidal Adriana C., Brenda Hernandez, Bartlett John A., Gammon Marilie D., Smith, Jennifer S, Francine Overcash, Nye, Monica D, Brandi Vasquez, Monica D Nye, Joseph Obure, Marilie D Gammon, Huang Zhiqing, Swai Britta, Olola Oneko, Mlay Pendo, Hernandez, Brenda, Wang Frances, Hernandez Brenda, Hoyo, Cathrine, Adriana C Vidal, Mlay, Pendo, Murphy, Susan K, Murphy, Susan K., Vidal, Adriana C, Pendo Mlay, Susan K Murphy, Smith, Jennifer S., Cathrine Hoyo, Gammon, Marilie D., Nye Monica D., Jennifer S Smith, Murphy Susan K., Wang, Frances, John A Bartlett, Huang, Zhiqing, Overcash Francine, Vidal, Adriana C., Bartlett, John A   +53 more
core   +2 more sources