Results 91 to 100 of about 222,132 (339)

Tumoral calcinosis in the cervical spine: a case report and review of the literature

Journal of Medical Case Reports, 2017
Background Tumoral calcinosis is rarely located in spine. A 55-year-old Japanese woman with cervical tumoral calcinosis is presented, along with a review of the literature relating to tumoral calcinosis in the spine. We discussed the etiology, diagnosis,
Rui Guo, Tatsuya Kurata, Tetsushi Kondo, Takao Imanishi, Tetsutaro Mizuno, Toshihiko Sakakibara, Yuichi Kasai   +6 more
doaj   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

Cervical Deformity Patients Have Baseline Swallowing Dysfunction but Surgery Does Not Increase Dysphagia at 3 Months: Results From a Prospective Cohort Study. [PDF]

, 2019
Study designProspective cohort study.ObjectivesMost studies of dysphagia in the cervical spine have focused on a degenerative patient population; the rate of dysphagia following surgery for cervical deformity (CD) is unknown.
Ames, Christopher P, Bao, Hongda, International Spine Study Group (ISSG), Iyer, Sravisht, Kim, Han Jo, Klineberg, Eric O, Lafage, Virginie, Mundis, Gregory M, Neuman, Brian J, Passias, Peter, Protopsaltis, Themistocles S, Smith, Justin S   +11 more
core  

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

Advanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva, Sara Duarte‐Silva, Pedro M. Martins, Beatriz Rodrigues, Débora Serrenho, Daniela Vilasboas‐Campos, Andreia Teixeira‐Castro, Julio Vieyto‐Nuñez, Joel Mieres‐Perez, Francisco Figueiredo, Martyna Podlasiak, Tatiana Van‐der‐Kellen, Joana Fraga, James Noble, Carter Lantz, Niki Sepanj, Daniela Monteiro‐Fernandes, Sara Guerreiro, Andreia Neves‐Carvalho, Joana Pereira‐Sousa, Frank‐Gerrit Klärner, Thomas Schrader, Joseph A. Loo, Annalisa Pastore, Elsa Sanchez‐Garcia, Gal Bitan, Ana Luísa Carvalho, Patrícia Maciel, Sandra Macedo‐Ribeiro   +28 more
wiley   +1 more source

Neurological evaluation of surgery cervical spine tumor at Viet Nam National Cancer Hospital

, 2022
Nguyen Thai Hoc, Nguyen Duc Lien
openalex   +1 more source

Overview and Prevention of Complications During Full-Endoscopic Cervical Spine Surgery [PDF]

, 2023
Young-Rak Kim, Junhoe Kim, Tae Hwan Park, Hangeul Park, Sum Kim, Chang-Hyun Lee, Kyoung‐Tae Kim, Chun Kee Chung, Chi Heon Kim   +8 more
openalex   +1 more source

Computer simulation of syringomyelia in dogs [PDF]

, 2018
Syringomyelia is a pathological condition in which fluid-filled cavities (syringes) form and expand in the spinal cord. Syringomyelia is often linked with obstruction of the craniocervical junction and a Chiari malformation, which is similar in both ...
AC Freeman, AR Brodbelt, B Williams, B Williams, B Williams, BA Martin, BA Martin, BA Martin, C Rusbridge, C Rusbridge, C Rusbridge, C Rusbridge, C Rusbridge, CA Schneider, CD Bertram, CD Bertram, CD Bertram, CD Bertram, CJ Driver, Clare Rusbridge, DJ Marino, DN Levine, EC Clarke, F Loth, Holger A. Volk, HS Chang, IM Vavasour, J Strahle, JD Heiss, JE Parker, Jelena Jovanovik, K Berkouk, K Chandler, KH Stoverud, LE Bilston, LE Bilston, M Heil, M Kim, M Perdiki, MA Stoodley, MJ Hezzell, N Alperin, NJ Alperin, NJ Fischbein, NS Elliott, NS Elliott, NSJ Elliott, NSJ Elliott, PW Carpenter, R Fric, Robert Lloyd, S Cerda-Gonzalez, S Cirovic, S Cirovic, S Heidari Pahlavian, S Loderstedt, S Yildiz, SJ Hemley, SP Knowler, SP Knowler, Srdjan Cirovic, TH Milhorat, TH Milhorat, W Kalata, WD Whetstone   +64 more
core   +3 more sources

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Evaluation of the efficiency of Minerva collar on cervical spine motions

Journal of Rehabilitation Sciences and Research, 2017
Background: Various types of cervical collars have being used to immobilize the cervical spine. There was no information regarding the effectiveness of Cervicothoracic collars (Minerva) on restriction of motions in cervical spine. Therefore, the purpose
Pegah Saddat Hosseini, Mohammad Taghi Karimi, Fatemeh Abnavi, Marzieh Golabbakhsh   +3 more
doaj   +2 more sources

Published- Post cervical spine surgery hyperpyrexia (108°F) in a patient with COVID-19: a case report

, 2023
Nimisha Cherunghattil, Chinmaya Kumar Panda, Habib Md Reazaul Karim, Mishal Dhawan   +3 more
openalex   +2 more sources