Results 31 to 40 of about 99,451 (312)

Critical evaluation of HPV16 gene copy number quantification by SYBR green PCR [PDF]

, 2008
Background: Human papilloma virus (HPV) load and physical status are considered useful parameters for clinical evaluation of cervical squamous cell neoplasia. However, the errors implicit in HPV gene quantification by PCR are not well documented. We have
Ng, G, Teschendorff, A, Stanley Margaret, Stanley, M, Coleman, N, Ng Grace, Herdman Michael T, Herdman, MT, Pett, MR, Foster, N, Roberts Ian, Teschendorff Andrew, Coleman Nicholas, Roberts, I, Pett Mark R, Foster Nicola   +15 more
core   +1 more source

The Value of Model Based on Radiomics Features of T2-weighted Imaging and Clinical Feature in Diagnosing the Depth of Stromal Invasion of Cervical Squamous Cell Carcinoma

Xiehe Yixue Zazhi, 2021
Objective  To investigate the prediction value of a clinical-radiomics model based on T2- weighted imaging (T2WI) and clinical features for diagnosing deep stromal invasion (DSI) in patients with early-stage cervical squamous cell carcinoma.
REN Jing, HE Yonglan, LI Yuan, CAO Ying, XIA Chen, XIANG Yang, XUE Huadan, JIN Zhengyu   +7 more
doaj   +1 more source

The HPV cellular transactivator Brn-3a can be used to predict cervical adenocarcinoma and squamous carcinoma precancer lesions in the developed and developing worlds

, 2009
The cellular transactivator Brn-3a has previously been shown to be expressed at elevated levels in the cervix of women with squamous cell carcinoma of the cervix (SCC) and to activate the expression of HPV E6 mRNA.
Ndisang, D., Ashfaq Khan, Sindos, M., Lorenzato, F., Khan, A., Latchman, David S., Singer, A., Felipe Lorenzato, David S. Latchman, Daniel Ndisang, Michael Sindos, Albert Singer   +11 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Squamous cell carcinoma with sarcomatoid differentiation or carcinosarcoma of the uterine cervix associated with HPV33 infection: report of a rare case

Diagnostic Pathology, 2020
Background Squamous cell carcinoma is the most common malignant tumor of the uterine cervix with a well-documented link to infection with human papillomaviruses (HPV).
Jan Hrudka, Blanka Rosová, Michael J. Halaška   +2 more
doaj   +1 more source

Projectile vomiting as presentation of duodenal intramural metastasis from cervical cancerLearning points

Taiwanese Journal of Obstetrics & Gynecology, 2022
Objective: To report a case and review literature of bowel metastases from cervical squamous cell carcinoma. Case Report: A 49-year-old woman with a history of FIGO 2013 stage IVB cervical squamous cell carcinoma presented with refractory nausea ...
Yu-Hsiang Lin, Chih-Yi Hsu, Shin-E Wang, Kung-Yi Sung, Chun-Yu Liu   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Surgical management of oral squamous cell carcinoma infiltrating mandible [PDF]

, 2008
Progression of recent trends in mandible-preserving operations for the management of oral squamous cell carcinomas that infiltrate the mandible is rapid and accompanying studies give invaluable information concerning behavioral understanding of oral ...
Kim, Hyung Jun
core  

Epidermal Growth Factor Receptor substrate 8 (Eps8) controls Src/FAK-dependent phenotypes in squamous carcinoma cells [PDF]

, 2014
Eps8 is an actin regulatory scaffold protein increased in Squamous Cell Carcinoma (SCC) cells. It forms a complex with both Focal Adhesion Kinase (FAK) and c-Src in SCC cells derived from the DMBA/TPA model of skin carcinogenesis.
Schoenherr, Christina, Baillie, George S., Frame, Margaret, Heath, John K., Proby, Charlotte, Frame, Margaret C., Cunningham, Debbie L, Findlay, Jane E, Cunningham, Debbie L., Findlay, Jane E., Baillie, George S, Heath, John K, Serrels, Bryan, Frame, Margaret C   +13 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source