Results 51 to 60 of about 99,451 (312)

LncRNA PVT1 promotes the growth of HPV positive and negative cervical squamous cell carcinoma by inhibiting TGF-β1

Cancer Cell International, 2018
Background Our study aimed to investigate the role of lncRNA PVT1 in cervical squamous cell carcinoma. Materials and methods A total of 156 patients with cervical squamous cell carcinoma were enrolled in this study and human papillomavirus (HPV ...
Xiuli Wang, Guichan Wang, Lijuan Zhang, Jianglin Cong, Jianqing Hou, Chunyan Liu   +5 more
doaj   +1 more source

Squamous Cell Carcinoma Antigen for Monitoring Cervical Cancer

The International Journal of Biological Markers, 1988
The tumour-associated antigen was determined in the plasma of patients with squamous cell carcinoma (SCC) of the uterine cervix by radioimmunoassay. Setting a limit of 2 ng/ml, levels were abnormal in 13.4% of healthy controls, in 14% of patients with carcinoma in situ and in 62% of patients with invasive cervical SCC.
P, Schmidt-Rhode, K D, Schulz, G, Sturm, H, Häfner, H, Prinz, H J, Künzig   +5 more
openaire   +2 more sources

The use of a battery of examination methods for detection of cervical metastases in squamous cell carcinoma of the oral cavity [PDF]

, 2021
Introduction. In patients with squamous cell carcinoma of the orofacial area, the presence of cervical metastases represents a single most significant prognostic factor.
Štembírek, Jan, Jiri Stransky, Jakub Cvek, Resová, Kamila, Zuzana Cermakova, Kamila Resova, Pavel Hurnik, Martina Litschmanova, Jonszta, Tomáš, Cvek, Jakub, Litschmanová, Martina, Čermáková, Zuzana, Tomas Jonszta, Jan Stembirek, Hurník, Pavel, Kulnig, Michal, Stránský, Jiří, Michal Kulnig   +17 more
core   +1 more source

Targeting KDM3B Elicits Anti‐tumor Immunity by Alleviating SHP1–mediated STING Suppression in Triple–Negative Breast Cancer

Advanced Science, EarlyView.
P3FI–90 treatment targets KDM3B, reshapes the epigenetic landscape, and suppresses SHP1 expression, thereby activating STING–TBK1–IRF3–type I IFN signaling pathway. Consequently, CD8+ T cells are recruited to the tumor site and activated to produce IFN–γ and GZMB, leading to the killing of TNBC cells.
Xiaolong Wang, Wenhao Li, Yifei Wang, Ning Zhang, Bing Chen, Wenjing Zhao, Lijuan Wang, Dan Luo, Qifeng Yang   +8 more
wiley   +1 more source

HPV-associated squamous cell carcinoma and adenocarcinoma in distinct cervical sites: a case report

BMC Infectious Diseases
Background The synchronous occurrence of adenocarcinoma and squamous cell carcinoma in distinct cervical regions is exceptionally rare. This report highlights a case of HPV-associated adenocarcinoma and squamous cell carcinoma at distinct sites in a ...
Huihui Chen, Qingyi Wang, Min Kang, Wei Huang, Hao Zhang, Jiaxin Li, Donghan Xu, Lin Zhao, Bowen Wu, Xin Lin, Liqi Li, Yuhong Zheng, Yihao Niu, Jiaqi Zhou, Donghui Huang, Peiyu Yan   +15 more
doaj   +1 more source

The Adler grade by Doppler ultrasound is associated with clinical pathology of cervical cancer: Implication for clinical management.

PLoS ONE, 2020
OBJECTIVE:To analyze the relationship of Adler grade by transvaginal color Doppler flow imaging (TV-CDFI) and the clinical pathological parameters of patients with cervical cancer, and to identify the value of Adler grade in the diagnosis and treatment ...
Dehong Che, Zhirong Yang, Hong Wei, Xuedong Wang, Jiayin Gao   +4 more
doaj   +1 more source

Cervical cancer screening programs in Latin America and the Caribbean. [PDF]

, 2008
Latin America and the Caribbean (LAC) have a significant burden of cervical cancer. Prophylactic human papillomavirus (HPV) vaccines are an opportunity for primary prevention and new screening methods, such as new HPV DNA testing, are promising ...
Gamboa, Oscar A, Pereira, Ana, Almonte, Maribel, Ferrer, Elena, Jerónimo, José, Murillo, Raul, Pereira Scalabrino, Ana, Lazcano Ponce, Eduardo, Gamboa, Oscar A., Lazcano-Ponce, Eduardo   +9 more
core   +1 more source

CEBPG‐Mediated Palmitic Acid Adaptation of Cancer‐Associated Fibroblasts Drives Metastasis of Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study reveals a metabolic signaling axis in the OSCC microenvironment where palmitic acid (PA) drives the activation of CAFs. PA uptake triggers CEBPG‐dependent epigenetic remodeling to upregulate ERN1 and TMBIM6, thereby mitigating ER stress. This adaptive program sustains CAF survival and the pro‐metastatic phenotype, establishing this pathway ...
Yiling Duan, Yitong Li, Yufei Wu, Xiao Yang, Rui Li, Hui Zhao, Zhengjun Shang   +6 more
wiley   +1 more source

Trends in cervical cancer incidence and mortality in the United States, 1975–2018: a population-based study

Frontiers in Medicine
BackgroundCervical cancer incidence and mortality rates in the United States have substantially declined over recent decades, primarily driven by reductions in squamous cell carcinoma cases. However, the trend in recent years remains unclear.
Xianying Cheng, Ping Wang, Li Cheng, Feng Zhao, Jiangang Liu   +4 more
doaj   +1 more source

Proteomic identification of potential biomarkers for cervical squamous cell carcinoma and human papillomavirus infection

Tumor Biology, 2017
It is known that high-risk human papillomavirus infection is the main etiological factor in cervical carcinogenesis. However, human papillomavirus screening is not sufficient for early diagnosis.
Song Qing, Wuniqiemu Tulake, Mingfang Ru, Xiaohong Li, Reziwanguli Yuemaier, Dilare Lidifu, Aierken Rouzibilali, Axiangu Hasimu, Yun Yang, Reziya Rouziahong, Halmurat Upur, Abulizi Abudula   +11 more
doaj   +1 more source