Results 41 to 50 of about 475,707 (262)

Eating the elephant whole or in slices: views of participants in a smoking cessation intervention trial on multiple behaviour changes as sequential or concurrent tasks [PDF]

open access: yes, 2012
Background: This paper explores smoking cessation participants’ perceptions of attempting weight management alongside smoking cessation within the context of a health improvement intervention implemented in Glasgow, Scotland.
Koshy Preethi   +9 more
core   +1 more source

Factors associated with abstinence after a recent smoking cessation attempt across 28 European Union member states [PDF]

open access: yes, 2021
Introduction: There is a lack of information regarding factors associated with successful smoking cessation on a population and European Union (EU)-wide level.
Cheung, Chung-Mei M   +5 more
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Risk factors for cessation of breastfeeding

open access: yesAl-Azhar Assiut Medical Journal, 2019
Introduction The Kingdom of Saudi Arabia is advancing quickly in all parts of life and health care. Nonetheless, breastfeeding is said to be on the deterioration. Patients and methods A case–control study was carried out to evaluate the risk factors that
Hussein Koura
doaj   +1 more source

Tobacco and Anaesthesia

open access: yesNMO Journal, 2023
Smoking increases the risk of perioperative morbidity and mortality in a dose-dependent manner. Cigarette smoke has more than 4500 chemicals that have detrimental effects on various organ systems.
Dr. Motghare Abhilasha, Sumit Bansal
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Expanding the reach of the Quitline by engaging volunteers to market it in hospitals and shopping venues – a pilot study

open access: yesTobacco Induced Diseases, 2015
Background In Canada, although there are periodic media campaigns to raise awareness of Quitlines, these services are underused. We sought to determine if a dedicated kiosk, similar to that used in the retail industry but staffed by volunteers trained in
Fadi Hammal   +3 more
doaj   +1 more source

GPs' views on new national smoking cessation guidelines [PDF]

open access: yes, 2001
Objectives: To assess GPs? views on recently published national smoking cessation guidelines that form the foundation of the government?s smoking cessation strategy.Design: Postal survey of a random sample of GPs.
McEwen, A, Akotia, N, West, R
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

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