Results 1 to 10 of about 119,123 (196)
The cfr and cfr-like multiple resistance genes
The Cfr methyl transferase causes an RNA methylation of the bacterial ribosomes impeding reduced or abolished binding of many antibiotics acting at the peptidyl transferase center. It provides multi-resistance to eight classes of antibiotics, most of which are in clinical and veterinary use.
B. Vester
semanticscholar +5 more sources
Detection of linezolid resistance cfr gene among MRSA isolates
Background: Linezolid (Oxazolidinones) is commonly used against a variety of Gram-positive infections, especially methicillin-resistant Staphylococcus aureus (MRSA).
Muneeba Wali +7 more
doaj +2 more sources
Poly-ether-ether-ketone (PEEK) has several approving mechanical properties; however, for certain demanding applications such as automotive, PEEK does not exhibit the required strength.
Prabaha Sikder, Surendrasingh Y Sonaye
exaly +2 more sources
This paper aimed to investigate the molecular epidemiological features of the cfr gene in E. coli isolates in a typical swine farm during 2014–2017. A total of 617 E. coli isolates were screened for the cfr gene using PCR amplification.
Jian-Hua Liu, Zhenbao Ma
exaly +2 more sources
Spreading of cfr-Carrying Plasmids among Staphylococci from Humans and Animals.
The multidrug resistance gene cfr mediates resistance to multiple antimicrobial agents, including linezolid. Plasmids are the preferred vector for the dissemination of cfr.
Jia Chang Cai, Rong Zhang, Yang Wang
exaly +3 more sources
Cfr is a radical S-adenosyl-l-methionine (SAM) enzyme that confers cross-resistance to antibiotics targeting the 23S rRNA through hypermethylation of nucleotide A2503.
Cesar Rodriguez +2 more
exaly +2 more sources
The plasmid-borne cfr gene, mediating multiple drug resistance (MDR), has been observed in many Gram-positive bacteria. The prevalence of cfr and its co-occurrence with additional antimicrobial resistance (AMR) determinants in Escherichia coli is an ...
Biao Tang, Min Yue, Yuehong Wu
exaly +3 more sources
A novel integrative and conjugative element in Streptococcus pyogenes carries a cfr-like gene associated with linezolid resistance in other species [PDF]
Treatment of severe invasive Streptococcus pyogenes infections has historically relied on β-lactam antibiotics with adjunctive clindamycin. Rising rates of lincosamide resistance have led to adoption of linezolid as an alternative adjunctive therapy ...
Daniel B. Amusin +12 more
doaj +2 more sources
We investigated cfr-positive and -negative MRSA strains isolated from animals and humans in different geographical areas of China, from 2011 to 2016. Twenty cfr-positive strains (15.6%) were identified from 128 MRSA strains including 17 from food animals
Shu-Min Li +14 more
doaj +2 more sources
ObjectiveThe aim was threefold: 1) expound the independent physiological parameters that drive FFR, 2) elucidate contradictory conclusions between fractional flow reserve (FFR) and coronary flow reserve (CFR), and 3) highlight the need of both FFR and ...
Damien Garcia +8 more
doaj +2 more sources

