Results 141 to 150 of about 71,270 (242)

Ligand-based virtual-screening identified a novel CFTR ligand which improves the defective cell surface expression of misfolded ABC transporters

Frontiers in Pharmacology
Cystic fibrosis (CF) is a monogenetic disease caused by the mutation of CFTR, a cAMP-regulated Cl− channel expressing at the apical plasma membrane (PM) of epithelia.
Shogo Taniguchi, Francois Berenger, Yukako Doi, Ayana Mimura, Yoshihiro Yamanishi, Tsukasa Okiyoneda   +5 more
doaj   +1 more source

CFTR mechanism [PDF]

Nature, 1992
M. A. McPHERSON, R. L. DORMER
openaire   +1 more source

Development of CpG-Depleted CFTR Plasmid-Based Nanoparticles for Nonviral Gene Therapy in Lung Cystic Fibrosis Disease. [PDF]

J Gene Med
Qiu B, Lorino M, Li Y, He Z, Wang X, Wang W, Lara-Sáez I.   +6 more
europepmc   +1 more source

Distinct CFTR Mutation Spectrum and Atypical Clinical Presentations in Chinese Patients with Cystic Fibrosis. [PDF]

Int J Mol Sci
Wang Z, Zuo G, Shi Y, Zhao Y, Fan X, Hou X, Wu Q.   +6 more
europepmc   +1 more source

RFFL-mediated protein quality control limits functional rescue of TRID-CFTR modulator combination therapy for cystic fibrosis nonsense mutations. [PDF]

Cell Mol Life Sci
Tateishi H, Doi Y, Kamada Y, Okiyoneda T.   +3 more
europepmc   +1 more source

Large variations in total and allele-specific transcript expression in a disease mutation-independent manner. [PDF]

Sci Rep
Freyberg M, Bewig M, Bampi GB, Manfredi C, Joshi D, Rauscher R, Hong JS, Große-Onnebrink J, Sutharsan S, Stehling F, Bobis I, Ballmann M, Sorscher EJ, Ignatova Z.   +13 more
europepmc   +1 more source

Tracking early cystic fibrosis in the new era. [PDF]

ERJ Open Res
Anagnostopoulou P, Rovira-Amigo S.
europepmc   +1 more source

Cutaneous Symptoms of Cystic Fibrosis: A Narrative Review. [PDF]

Clin Cosmet Investig Dermatol
Piątkiewicz M, Olędzka B, Wołkowicz A, Durmaj A, Rudnicka L.   +4 more
europepmc   +1 more source

Clinical characteristics of pulmonary non-tuberculous mycobacterial disease with <i>CFTR</i> variants in the Japanese population. [PDF]

BMJ Open Respir Res
Nagao G, Namkoong H, Tanaka H, Asakura T, Hara A, Fukunaga N, Kaji M, Azekawa S, Nakagawara K, Morita A, Kamata H, Nishimura T, Miya F, Kosaki K, Fukunaga K, Holland SM, Hasegawa N.   +16 more
europepmc   +1 more source

Decoding liver injury in cystic fibrosis: How to tell drug-induced liver injury from cystic fibrosis liver disease. [PDF]

World J Gastroenterol
Lee J, Yekula A, Wexler A, Zhuang W, Elangovan A, Rosario J, Burger P, Ramaraju G, Addissie B, Lim N, Narkewicz MR, Twohig P.   +11 more
europepmc   +1 more source