Results 191 to 200 of about 1,459,532 (261)

RFFL-mediated protein quality control limits functional rescue of TRID-CFTR modulator combination therapy for cystic fibrosis nonsense mutations. [PDF]

Cell Mol Life Sci
Tateishi H, Doi Y, Kamada Y, Okiyoneda T.   +3 more
europepmc   +1 more source

The impact of CFTR modulator triple therapy on type 2 inflammatory response in patients with cystic fibrosis. [PDF]

Allergy Asthma Clin Immunol, 2023
Mehta AM, Lee I, Li G, Jones MK, Hanson L, Lonabaugh K, List R, Borish L, Albon DP.   +8 more
europepmc   +1 more source

Quantitative Systems Toxicology Predicts Ivacaftor-Induced Oxidative Stress Contributes to CFTR Modulator Hepatotoxicity. [PDF]

Clin Pharmacol Ther
Shi A, Cornwell C, Yang K, Beringer PM.
europepmc   +1 more source

Short-term monitoring of CFTR modulator therapy in adults and children with cystic fibrosis using low and ultra-low-dose lung CT. [PDF]

Radiol Med
Maccioni F, Cimino G, Longhi A, Busato L, Valenti A, Bottino L, Rutigliano M, Alessandrelli R, Landini N, Catalano C.   +9 more
europepmc   +1 more source

Real-life impact of highly effective CFTR modulator therapy in children with cystic fibrosis. [PDF]

Front Pharmacol, 2023
Olivier M, Kavvalou A, Welsner M, Hirtz R, Straßburg S, Sutharsan S, Stehling F, Steindor M.   +7 more
europepmc   +1 more source

Theratyping as a tool to guide clinical decision-making in patients with suspected cystic fibrosis and variants currently ineligible for CFTR modulator therapy. [PDF]

Respir Med
Gannon RM, Wright BA, Bettis BA, Teresi ME, Fischer AJ, Weiner RL, Peña T, Hornick DB, Thornell IM, Rehman T, Pezzulo AA.   +10 more
europepmc   +1 more source

Changes in Sleep in Children and Adults with Cystic Fibrosis and Primary Ciliary Dyskinesia over Time and after CFTR Modulator Therapy. [PDF]

J Clin Med, 2023
Cohen-Cymberknoh M, Lehavi M, Gileles-Hillel A, Atia O, Breuer O, Reiter J.   +5 more
europepmc   +1 more source

Respiratory Muscle Function in Children and Adolescents with Cystic Fibrosis in the Era of CFTR Modulator Therapies. [PDF]

Children (Basel)
García-Pérez-de-Sevilla G, Blanco Velasco Á, Yvert T, Sanz-Santiago V, Tirado AM, López Neyra A, de Manuel C, Ruiz Valbuena M, Pérez-Ruiz M.   +8 more
europepmc   +1 more source

Antisense oligonucleotide targeting the E3 ligase RFFL potentiates CFTR modulator efficacy in CF primary bronchial epithelial cells. [PDF]

Mol Ther Nucleic Acids
Hinata D, Kai Y, Fukuda R, Kamada Y, Kasahara Y, Sasaki K, Yoshida T, Obika S, Inoue T, Okiyoneda T.   +9 more
europepmc   +1 more source

CFTR modulator therapy drives microbiome restructuring through improved host physiology in cystic fibrosis: the IMMProveCF phase IV trial. [PDF]

Nat Commun
Knoll RL, Brauny MM, Robert E, Cloos L, Waser L, Hilbert K, Ulmer N, Hillen B, Birkner T, Bartolomaeus TUP, Nitsche O, Jarquín-Díaz VH, Lynch S, Gehring S, Maier L, Poplawska K, Forslund-Startceva SK.   +16 more
europepmc   +1 more source