Results 31 to 40 of about 4,681 (114)

CFTR Modulator Response in Nasal Organoids Derived from People with Cystic Fibrosis. [PDF]

Cells
Lo Cicero S, Castelli G, Ceci A, Cerio AM, Blaconà G, Virgulti M, Allushi S, Sette G, Spadaro F, Amato F, Melotti P, Sorio C, Cimino G, Biffoni M, Lucarelli M, Eramo A.   +15 more
europepmc   +1 more source

Long-Term Follow-Up of Health-Related Quality of Life and Short-Term Intervention with CFTR Modulator Therapy in Adults with Cystic Fibrosis: Evaluation of Changes over Several Years with or without 33 Weeks of CFTR Modulator Therapy. [PDF]

Healthcare (Basel), 2023
Gruber W, Welsner M, Blosch C, Dillenhoefer S, Olivier M, Brinkmann F, Koerner-Rettberg C, Sutharsan S, Mellies U, Taube C, Stehling F.   +10 more
europepmc   +1 more source

Transcriptomic and functional responses of the cystic fibrosis airway epithelium to CFTR modulator therapy. [PDF]

JCI Insight
Vladar EK, Gillen AE, Yadav S, Murphree MR, Baraghoshi D, Harris JK, Pruesse E, Niemiec SS, Wilson AW, Hisert KB, Humphries SM, Strand M, Lynch DA, Seibold MA, Beswick DM, Taylor-Cousar JL.   +15 more
europepmc   +1 more source

The impact of CFTR modulator triple therapy on type 2 inflammatory response in patients with cystic fibrosis. [PDF]

Allergy Asthma Clin Immunol, 2023
Mehta AM, Lee I, Li G, Jones MK, Hanson L, Lonabaugh K, List R, Borish L, Albon DP.   +8 more
europepmc   +1 more source

Functional, Cohort-Level Assessment of CFTR Modulator Responses Using Biobanked Nasal Epithelial Cells from Individuals with Cystic Fibrosis. [PDF]

J Pers Med
Aalbers BL, Amatngalim GD, Aarts EM, Rodenburg LW, den Hertog-Oosterhoff LA, Heijerman HGM, Beekman JM.   +6 more
europepmc   +1 more source

Real-world disparities and ethical considerations with access to CFTR modulator drugs: Mind the gap! [PDF]

Front Pharmacol, 2023
Zampoli M, Morrow BM, Paul G.
europepmc   +1 more source

RFFL-mediated protein quality control limits functional rescue of TRID-CFTR modulator combination therapy for cystic fibrosis nonsense mutations. [PDF]

Cell Mol Life Sci
Tateishi H, Doi Y, Kamada Y, Okiyoneda T.   +3 more
europepmc   +1 more source

Real-life impact of highly effective CFTR modulator therapy in children with cystic fibrosis. [PDF]

Front Pharmacol, 2023
Olivier M, Kavvalou A, Welsner M, Hirtz R, Straßburg S, Sutharsan S, Stehling F, Steindor M.   +7 more
europepmc   +1 more source

Quantitative Systems Toxicology Predicts Ivacaftor-Induced Oxidative Stress Contributes to CFTR Modulator Hepatotoxicity. [PDF]

Clin Pharmacol Ther
Shi A, Cornwell C, Yang K, Beringer PM.
europepmc   +1 more source

Combined CFTR modulator therapies are linked with anabolic benefits and insulin-sparing in cystic fibrosis-related diabetes. [PDF]

J Clin Transl Endocrinol, 2023
Lurquin F, Gohy S, Hermans MP, Preumont V.   +3 more
europepmc   +1 more source