Results 151 to 160 of about 7,856 (243)
Acta Paediatrica, Volume 115, Issue 6, Page 1283-1289, June 2026.ABSTRACT Aim Children with cystic fibrosis (CF) face substantial daily treatment burdens and the effects of transmembrane conductance regulator modulators on these have not been sufficiently described. We evaluated changes in treatment burden after elexacaftor tezacaftor ivacaftor (ETI) was initiated.
Marcus Svedberg +5 more
wiley +1 more source
Cell Proliferation, Volume 59, Issue 6, June 2026.The endoplasmic reticulum membrane protein complex (EMC) is an evolutionarily conserved, multi‐subunit transmembrane protein complex crucial to membrane protein biogenesis and cellular protein quality control. This review systematically examines the structure, functions and disease‐associated regulatory mechanisms of EMC across multiple organ systems ...
Yan Qiao +6 more
wiley +1 more source
Profile of tezacaftor/ivacaftor combination and its potential in the treatment of cystic fibrosis
Therapeutics and Clinical Risk Management, 2019 Dejene Shiferaw,* Shoaib Faruqi*Department of Respiratory Medicine, Hull University Teaching Hospitals NHS Trust, Cottingham HU16 5JQ, UK *These authors contributed equally to this workCorrespondence: Shoaib FaruqiDepartment of Respiratory Medicine ...
Shiferaw D, Faruqi S
doaj
Potential Relationship Between YTHDF3 and CFTR in Myocardial Ischemia–Reperfusion Injury
Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.ABSTRACT Myocardial ischemia–reperfusion injury (MIRI) is a common pathophysiological process in reperfusion therapy following myocardial infarction. It exacerbates myocardial damage and negatively impacts patient prognosis. This study aims to explore potential regulatory targets and related mechanisms in MIRI.
Baoxin Tang +4 more
wiley +1 more source
Physiological Reports, Volume 14, Issue 11, June 2026.Abstract Despite the ubiquitous use of monosodium glutamate (MSG) as a food additive, its specific effects on intestinal health and disease remain largely unclear. Here we found mucosal application of MSG induced an upward intestinal short‐circuit current (Isc) in the murine ileum, which was significantly reduced by extracellular Cl−, Na+, and Ca2 ...
Yunxian Wang +4 more
wiley +1 more source
, 2020 Excessive inflammation by phagocytes during Aspergillus fumigatus infection is thought to promote lung function decline in CF patients. CFTR modulators have been shown to reduce A.
AJ Currie (21920879) +4 more
core
, 2016 Béla Z Schmidt,1 Jérémy B Haaf,2 Teresinha Leal,2 Sabrina Noel,2 1Stem Cell Biology and Embryology, Department of Development and Regeneration, Katholieke Universiteit Leuven, Leuven, 2Louvain Center for Toxicology and Applied ...
Leal T, Haaf JB, Noel S, Schmidt BZ
core
Impact of COVID-19 and CFTR Modulators on Cystic Fibrosis: A Real-World Analysis of Care Patterns. [PDF]
Pediatr PulmonolHinton AC +3 more
europepmc +1 more source
Beyond BMI: Nutritional Recovery and Functional Implications of CFTR Modulators in Cystic Fibrosis. [PDF]
Biology (Basel)Linguiti G +6 more
europepmc +1 more source