Results 171 to 180 of about 12,522 (293)
Clinical Transplantation, Volume 40, Issue 1, January 2026.ABSTRACT Background: In pediatric lung transplantation, the ability to estimate the projected waiting time could be particularly helpful for candidates and physicians. A score to predict waiting time has yet to be developed in this field. The purpose of this study was to create a score that predicts waitlist time for pediatric patients who are listed ...
Jose Ramirez +2 more
wiley +1 more source
Cystic Fibrosis: Treatment with CFTR Modulators
, 2023 CFTR modulators have been a groundbreaking new invention starting with the approval of the CFTR corrector Ivacaftor in 2012. Nowadays, up to 90% of CF patients have the potential ability to get treated by an appropriate CFTR modulator. Ivacaftor showed significant improvement in the treatment of CF patients with gating mutations, especially in G551D ...
openaire +2 more sources
Annals of HepatologyConflict of interest: No Introduction and Objectives: The impact of cystic fibrosis (CF) transmembrane conductance regulator (CFTR) modulators on the natural history of liver disease is unknown.
MANUEL MENDIZABAL +6 more
doaj +1 more source
Chaperones as integrators of cellular networks: Changes of cellular integrity in stress and diseases
, 2008 Cellular networks undergo rearrangements during stress and diseases. In un-stressed state the yeast protein-protein interaction network (interactome) is highly compact, and the centrally organized modules have a large overlap.
Albanese +54 more
core +2 more sources
TDP‐43 proteinopathies and neurodegeneration: insights from Caenorhabditis elegans models
The FEBS Journal, Volume 293, Issue 2, Page 348-384, January 2026.The manuscript explores structural and functional features of TDP‐43 and its worm homologue, TDP‐1, highlighting conserved and divergent structural and functional features. Using genetically engineered C. elegans models, key pathological features of TDP‐43 proteinopathies—including aggregation, neurodegeneration, and motor deficits—are recapitulated ...
Ghulam Jeelani Pir +7 more
wiley +1 more source
Welfare Indicators for Aquaculture Research: Toolboxes for Five Farmed European Fish Species
Reviews in Aquaculture, Volume 18, Issue 1, January 2026.ABSTRACT Refining approaches to measuring, monitoring and appraising animal welfare in aquaculture research is key to (i) protecting and optimizing it, (ii) documenting the severity of how and when it deviates, and (iii) ensuring good scientific quality, reliable results and reproducibility, amongst other factors.
Chris Noble +50 more
wiley +1 more source
The PROSPECT Is Bright for CFTR Modulators
Annals of the American Thoracic Society, 2021 Kristina Montemayor, Noah Lechtzin
openaire +2 more sources
Current strategies for the long-term assessment, monitoring, and management of cystic fibrosis patients treated with CFTR modulator therapy [PDF]
, 2016 J.S. Elborn +4 more
openalex +1 more source
Beyond the Surface: Novel Therapy Approach for Pancreatitis in the Setting of CFTR Dysfunction
Case Reports in Gastrointestinal Medicine, Volume 2026, Issue 1, 2026.Objectives Despite cystic fibrosis transmembrane conductance regulator (CFTR) proteins being present throughout the entire body and organ systems, typical presentation of cystic fibrosis (CF) involves lung disease. We report a series of individuals that were referred to our CF clinic for evaluation following a diagnosis of chronic pancreatitis or acute
Brittany A. Wright +4 more
wiley +1 more source