Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro +14 more
wiley +1 more source
Comprehensive transduceromic profiling of NOP receptor ligands at different Gα subunits
Abstract Background and Purpose The nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) is an opioid receptor family member with distinct pharmacology and broad therapeutic potential. NOP receptors regulate functions such as nociception, stress reactivity, reward, mood, autonomic tone, immunity and sleep/wake cycle.
Davide Malfacini +9 more
wiley +1 more source
Structural basis of undecaprenyl phosphate glycosylation leading to polymyxin resistance in Gram-negative bacteria. [PDF]
Ashraf KU +8 more
europepmc +1 more source
Avaliação dos teores de cafeína em clones de erva mate por cromatografia gasosa acoplada a espectrometria de massa (CG-EM). [PDF]
AMBONI, R. D. de M. C. +2 more
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Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK‐air Study
In a study assessing mobile health data, (i) adherence to rhinitis medication was highest for oral antihistamines and lowest for azelastine‐fluticasone, (ii) in weeks of partial adherence, azelastine‐fluticasone was associated with lower levels of reported rhinitis symptoms than other medication classes.
Bernardo Sousa‐Pinto +121 more
wiley +1 more source
Identificação em mistura de piperamidas em folhas, caule e raízes de Piper ottonoides por CG-EM e RMN 1D e 2D. [PDF]
GUIMARÃES, E. F. +5 more
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ABSTRACT Objectives To evaluate whether adding a connective tissue graft (CTG) to guided bone regeneration (GBR) improves clinical and radiographic outcomes in surgical peri‐implantitis treatment. Materials and Methods Thirty‐two patients with peri‐implantitis were randomly assigned to receive GBR and CTG (test group, TG) or GBR alone (control group ...
Lucrezia Paterno Holtzman +7 more
wiley +1 more source
Auditory skills and neural encoding in children with speech sound disorder. [PDF]
Rohers DE, Keske-Soares M, Biaggio EPV.
europepmc +1 more source
Análises multiresíduos de agrotóxicos em tomate (Lycopersicon esculentum Mill) utilizando CG-EM e monitoramento [PDF]
openaire +1 more source
Derivatizações na análise simultânea de ácido 3-indol-acético e triptofano em tecido vegetal por cromatografia gasosa acoplado a espectrometria de massa. [PDF]
HANSEL, F. A., MELO, T. O. de
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