Results 51 to 60 of about 91 (71)
Additional file 12. Raw data for Fig. 3k. As indicated, the chemiluminescence scans of H3K4me3 and total histone H3 blots are shown either alone or as an overlay with the white light image that shows the molecular weight markers.
Patel, Manthan +3 more
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Additional file 13. Raw data for Fig. 3l. Uncropped view of the ethidium bromide-stained agarose gel scan (including the wells and molecular weight marker as indicated) with samples as indicated at the top. The two lanes to the extreme right are empty.
Patel, Manthan +3 more
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CGGBP1-CTCF dynamics in regulation of chromosomal interactions
Umashankar Singh +3 more
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Abstract The formation of G-quadruplexes (G4) is fundamentally linked to GC content of the DNA. There is little evidence for evolutionary selection of G4 stabilizers; G4 formation depends strictly on inherent sequence properties. Vertebrate promoters are notable for their consistently high GC-content as well as pronounced G/C strand ...
Praveen Kumar, Umashankar Singh
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Genome-wide CpG and non-CpG methylation regulation by CGGBP1
Umashankar Singh +3 more
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CGGBP1 regulates cell cycle in cancer cells [PDF]
CGGBP1 is a CGG-triplet repeat binding protein, which affects transcription from CGG-triplet-rich promoters such as the FMR1 gene and the ribosomal RNA gene clusters. Earlier, we reported some previously unknown functions of CGGBP1 in gene expression during heat shock stress response.
Bengt Westermark +2 more
exaly +4 more sources
Some of the next articles are maybe not open access.
CGGBP1 is a nuclear and midbody protein regulating abscission
Experimental Cell Research, 2011Abscission marks the completion of cell division and its failure is associated with delayed cytokinesis and even tetraploidization. Aberrant abscission and consequential ploidy changes can underlie various diseases including cancer. Midbody, a transient structure formed in the intercellular bridge during telophase, contains several proteins including ...
Bengt Westermark, Umashankar Singh
exaly +3 more sources
CGGBP1 mitigates cytosine methylation at repetitive DNA sequences [PDF]
CGGBP1 is a repetitive DNA-binding transcription regulator with target sites at CpG-rich sequences such as CGG repeats and Alu-SINEs and L1-LINEs. The role of CGGBP1 as a possible mediator of CpG methylation however remains unknown. At CpG-rich sequences cytosine methylation is a major mechanism of transcriptional repression.
Bengt Westermark +2 more
exaly +6 more sources
Defining the role of the CGGBP1 protein in FMR1 gene expression [PDF]
Fragile X syndrome is the most common heritable form of intellectual disability and is caused by the expansion over 200 repeats and subsequent methylation of the CGG triplets at the 5' UTR of the FMR1 gene, leading to its silencing. The epigenetic and molecular mechanisms responsible for FMR1 gene silencing are not fully clarified.
Pietro Chiurazzi +2 more
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Gene structure and expression of the 5′-(CGG)n-3′-binding protein (CGGBP1)
The human nuclear 5'-(CGG)(n)-3'-binding protein (CGGBP1) influences the expression of the fragile X mental retardation (FMR1) gene by specifically interacting with the 5'-(CGG)(n>5)-3' repeat in its 5' untranslated region. Here, we show that CGGBP1 binds to 5'-(CGG)(n)-3' repeats with n>or=5 and to interrupted repeats.
Walter Doerfler, Birgit Schmitz
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