Results 31 to 40 of about 91 (71)
European Journal of Neuroscience, Volume 61, Issue 10, May 2025.This study used a rat model of absence epilepsy, Genetic Absence Epilepsy Rat from Strasbourg (GAERS), to investigate the effects of gestational valproate exposure on early postnatal brain cortex and lateral choroid plexus transcriptomes. Results showed distinct differential gene expression patterns between the two tissues, with substantially more ...
Fiona Qiu +4 more
wiley +1 more source
, 2020 Additional file 2. Chemiluminescence scan at a weaker intensity of DBID blots shown in Fig. 3a. The well marked with a red X symbol contains a sample irrelevant to the experiments described. The names of the inhibitors are indicated at the top of each well.
Patel, Manthan +3 more
+5 more sources
, 2020 Additional file 8. CGGBP1 depletion in GM02639 cells: GM02639 cells were transfected with non-targeting or CGGBP1-targeting siRNA twice at 24 and 72 h post-seeding. Cells were harvested at 96 h. Immunoblotting results for CGGBP1 (upper panel) and GAPDH (lower panel) show approximately 55% knockdown of CGGBP1 when normalized to the level of GAPDH.
Patel, Manthan +3 more
openaire +1 more source
Clinical and Translational Medicine, Volume 14, Issue 8, August 2024.This study unveils the cellular diversity within the adult human adrenal gland using single‐nuclei RNA sequencing and spatial transcriptome data. Analysis of the adult human adrenal gland identifies new cell populations and key pathways governing adrenal homeostasis.
Barbara Altieri +13 more
wiley +1 more source
, 2020 Additional file 11. Repeat content analysis in HEK293T CT and KD MeDIP DNA shows subfamily-specific methylation changes: Methylation bin frequency plots for HEK293T CT and KD. CT and KD reads for each methylation bin (From 5 to 30) were merged and sequences for merged regions (> 150 bp long) were extracted and subjected to repeat identification. The
Patel, Manthan +3 more
openaire +1 more source
Physiological Reports, Volume 12, Issue 3, February 2024.Abstract Recurrent spontaneous abortion (RSA) is a serious condition that adversely affects women's health. Differentially expressed proteins (DEPs) in plasma of patients experiencing RSA is helpful to find new therapeutic targets and identified with mass spectrometry. In 57 DEPs, 21 were upregulated and 36 were downregulated in RSA.
Li Ji +9 more
wiley +1 more source
, 2020 Additional file 14 Quantitative PCR (double delta analysis of relative changes in levels of methylated DNA) on CT and KD DNA from human dermal fibroblasts shows widespread differences between CT and KD. (A) qPCR on HpaII-digested DNA (digests DNA flanking unmethylated cytosine) shows a significant (p < 0.05, n = 3 technical replicates, unpaired T ...
Patel, Manthan +3 more
openaire +1 more source
, 2020 Additional file 5. Methylation differences between CT and KD are discernible at small genomic length ranges. Genome-wide methylation signal distribution was compared between CT and KD by using “deeptools multiBigwigSummary”. Methylation signals were compared at bin sizes of 10 kb, 5 kb, 1 kb and 0.2 kb. Correlation between CT and KD was computed by the
Patel, Manthan +3 more
openaire +2 more sources
, 2020 Additional file 7. The MeDIP reads distribution for HEK293T CT and KD at low methylation signal bins (1 to 4): Lower methylation signal bins account for a major fraction of MeDIP reads. The frequency of the MeDIP reads for these bins with less than 5 methylation read signals were calculated separately from those in the range 5–30.
Patel, Manthan +3 more
openaire +1 more source
, 2020 Additional file 15. CpG SNPs in the entire AIM dataset and those mapping to the CTCF motifs undergoing AIM in GM02639 cells. The methylation changes at CTCF motifs are not linked to any detectable CpG SNPs within the motifs even if the flanking regions in the sequence reads harbour CpG SNPs.
Patel, Manthan +3 more
openaire +1 more source