Results 21 to 30 of about 311 (117)

HDAC inhibitor Givinostat targets DNA-binding of human CGGBP1 [PDF]

open access: yes, 2020
The antineoplastic agent Givinostat inhibits histone deacetylases. We present here our finding that the DNA-binding of human CGGBP1 is also inhibited by Givinostat. CGGBP1, a DNA-binding protein, is required for cancer cell proliferation. In our quest to
Patel, Manthan   +3 more
core   +3 more sources

MOESM2 of CGGBP1 regulates CTCF occupancy at repeats

open access: yes, 2019
Additional file 2: Figure S1. (A) Human juvenile fibroblasts co-immunostained for CGGBP1 (Green) and CTCF (Red). Nuclei were counterstained with DAPI (blue).
Manthan Patel (5476790)   +3 more
core   +2 more sources

Expanding the Spectrum of Canine Diffuse Large B‐Cell Lymphoma Genetic Aberrations Through Whole Genome Sequencing Analysis [PDF]

open access: yesVeterinary and Comparative Oncology, Volume 23, Issue 3, Page 346-357, September 2025.
ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) is one of the most prevalent haematological malignancies in both humans and dogs, characterised in both species by significant clinical heterogeneity and limited prognostic predictability. With the introduction of next‐generation sequencing (NGS) technologies in veterinary medicine over the past decade ...
Antonella Fanelli   +4 more
wiley   +2 more sources

MOESM1 of CGGBP1 regulates CTCF occupancy at repeats

open access: yes, 2019
Additional file 1: The supplementary tables with captions are presented in Additional file ...
Manthan Patel (5476790)   +3 more
core   +2 more sources

MOESM3 of CGGBP1 regulates CTCF occupancy at repeats

open access: yes, 2019
Additional file 3: Appendices I to VI in the Additional file 3 show the raw data and supporting information for the various experiments and analysis ...
Manthan Patel (5476790)   +3 more
core   +2 more sources

MOESM1 of Dynamic bimodal changes in CpG and non-CpG methylation genome-wide upon CGGBP1 loss-of-function

open access: yes, 2018
Additional file 1. A total of Tables S1 to S11 and Figures S1 to S7 with legends, details of methods and additional references are contained in the combined additional data ...
Manthan Patel (5476790)   +3 more
core   +2 more sources

CGGBP1-CTCF dynamics in regulation of chromosomal interactions

open access: yesCanadian Journal of Biotechnology, 2017
Manthan Patel   +3 more
core   +2 more sources

Dissecting Heterogeneity Reveals a Unique BAMBIhighMFGE8high Subpopulation of Human UC‐MSCs

open access: yesAdvanced Science, Volume 10, Issue 1, January 4, 2023., 2023
Large‐scale scRNA‐seq uncovers a unique BAMBIhighMFGE8high subpopulation hidden in heterogeneous human UC‐MSCs. It has special features in terms of phenotype, distinct transcriptomic profile, limited adipogenic differentiation potential, and unconventional immunological properties.
Hongwei Chen   +10 more
wiley   +1 more source

Structural and molecular characterization of paraventricular thalamic glucokinase‐expressing neuronal circuits in the mouse

open access: yesJournal of Comparative Neurology, Volume 530, Issue 11, Page 1773-1949, August 2022., 2022
By using a genetically modified mouse model and viral tracing approaches, we mapped both the anterograde and the retrograde projections of a subpopulation of neurons in the anterior paraventricular thalamic nucleus, molecularly defined by the expression of glucokinase (GckaPVT).
Sevasti Gaspari   +4 more
wiley   +1 more source

Structural analysis of random transgene integration in CHO manufacturing cell lines by targeted sequencing

open access: yesBiotechnology and Bioengineering, Volume 119, Issue 3, Page 868-880, March 2022., 2022
Targeted locus amplification (TLA) allows for accurate transgene integration site detection of CHO clones. Further, it provides comprehensive genetic information of the transgene locus including genomic rearrangements, deletions and translocations. Genes within or in close proximity to the integration site can be identified, which can have important ...
Anna Stadermann   +7 more
wiley   +1 more source

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