Results 21 to 30 of about 91 (71)

An Age‐Related Hearing Protection Locus on Chromosome 16 of BXD Strain Mice

open access: yesNeural Plasticity, Volume 2020, Issue 1, 2020., 2020
Inbred mouse models are widely used to study age‐related hearing loss (AHL). Many genes associated with AHL have been mapped in a variety of strains. However, little is known about gene variants that have the converse function—protective genes that confer strong resistance to hearing loss.
Qing Yin Zheng   +13 more
wiley   +1 more source

A Genome‐Wide Analysis of Long Noncoding RNAs in Circulating Leukocytes and Their Differential Expression in Type 1 Diabetes Patients

open access: yesJournal of Diabetes Research, Volume 2020, Issue 1, 2020., 2020
Long noncoding RNAs (lncRNAs) regulate gene expression at different levels in various diseases, including type 1 diabetes (T1D). However, the expression of circulating lncRNAs in leukocytes in T1D has not been well documented. To identify differentially expressed lncRNAs between T1D patients and healthy controls, RNA sequencing was performed on samples
Yihan Liu   +11 more
wiley   +1 more source

Bioinformatic screening for key miRNAs and genes associated with myocardial infarction

open access: yesFEBS Open Bio, Volume 8, Issue 6, Page 897-913, June 2018., 2018
Treatment of myocardial infarction (MI) has improved in recent years, but morbidity and mortality is still high. In this study, we used bioinformatics techniques to identify miRNA and genes potentially associated with MI, validating these results by quantitative RT‐PCR.
Ke Wu   +6 more
wiley   +1 more source

Identification of Novel Epigenetic Markers of Prostate Cancer by NotI‐Microarray Analysis

open access: yesDisease Markers, Volume 2015, Issue 1, 2015., 2015
A significant need for reliable and accurate cancer diagnostics and prognosis compels the search for novel biomarkers that would be able to discriminate between indolent and aggressive tumors at the early stages of disease. The aim of this work was identification of potential diagnostic biomarkers for characterization of different types of prostate ...
Alexey A. Dmitriev   +18 more
wiley   +1 more source

MOESM3 of CGGBP1 regulates CTCF occupancy at repeats

open access: yes, 2019
Additional file 3: Appendices I to VI in the Additional file 3 show the raw data and supporting information for the various experiments and analysis steps.
Patel, Divyesh   +3 more
openaire   +1 more source

Differential expression of CGGBP1 in amyotrophic lateral sclerosis.

open access: yes, 2022
Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression ...
openaire   +1 more source

MOESM1 of CGGBP1 regulates CTCF occupancy at repeats

open access: yes, 2019
Additional file 1: The supplementary tables with captions are presented in Additional file 1.
Patel, Divyesh   +3 more
openaire   +1 more source

MOESM2 of CGGBP1 regulates CTCF occupancy at repeats

open access: yes, 2019
Additional file 2: Figure S1. (A) Human juvenile fibroblasts co-immunostained for CGGBP1 (Green) and CTCF (Red). Nuclei were counterstained with DAPI (blue). Mean fluorescence intensities for CGGBP1 (green) and CTCF (red) were normalized along the line-marked segment and plotted using ImageJ.
Patel, Divyesh   +3 more
openaire   +1 more source

Expanding the Spectrum of Canine Diffuse Large B‐Cell Lymphoma Genetic Aberrations Through Whole Genome Sequencing Analysis

open access: yesVeterinary and Comparative Oncology, Volume 23, Issue 3, Page 346-357, September 2025.
ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) is one of the most prevalent haematological malignancies in both humans and dogs, characterised in both species by significant clinical heterogeneity and limited prognostic predictability. With the introduction of next‐generation sequencing (NGS) technologies in veterinary medicine over the past decade ...
Antonella Fanelli   +4 more
wiley   +1 more source

Additional file 3 of CGGBP1-regulated cytosine methylation at CTCF-binding motifs resists stochasticity

open access: yes, 2020
Additional file 3. Tabulation of the sequencing and alignment statistics for CT and KD MeDIP in HEK293T and GM02639.
Patel, Manthan   +3 more
openaire   +1 more source

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