Decreased soluble guanylate cyclase contributes to cardiac dysfunction induced by chronic doxorubicin treatment in mice [PDF]
Aims: The use of doxorubicin, a potent chemotherapeutic agent, is limited by cardiotoxicity. We tested the hypothesis that decreased soluble guanylate cyclase (sGC) enzyme activity contributes to the development of doxorubicin-induced cardiotoxicity ...
Allen, Kaitlin+15 more
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In Vitro Stimulation of Neutrophil Motility by Levamisole: Maintenance of cGMP Levels in Chemotactically Stimulated Levamisole-Treated Neutrophils [PDF]
Ronald Anderson+3 more
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Differential effects of cAMP and cGMP on in vitro epidermal cell growth [PDF]
Cynthia L. Marcelo
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The nitric oxide – guanylyl cyclase-1 – cyclic guanylate monophosphate (NO-GC-1–cGMP) pathway has emerged as a potential pathogenic mechanism for glaucoma, a common intraocular pressure (IOP)-related optic neuropathy characterized by the degeneration of ...
Lauren K. Wareham+10 more
doaj
Rise of cGMP by partial phosphodiesterase-3A degradation enhances cardioprotection during hypoxia
3′,5′-cyclic guanosine monophosphate (cGMP) is a druggable second messenger regulating cell growth and survival in a plethora of cells and disease states, many of which are associated with hypoxia. For example, in myocardial infarction and heart failure (
Nadja I. Bork+11 more
doaj
Cyclic Nucleotides and Growth Control in Cultured Mouse Cells: Correlation of Changes in Intracellular 3′:5′cGMP Concentration with a Specific Phase of the Cell Cycle [PDF]
W. Seifert, Philip S. Rudland
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Time Saving Protein Binding Assay for the Simultaneous Determination of Guanosine 3′:5′-monophosphate (cGMP) and Adenosine 3′:5′-monophosphate (cAMP) in Human Urine [PDF]
T. O. Kleine, U. Kroh
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215 GUANOSINE 3′: 5′- CYCLIC MONOPHOSPHATE (cGMP) IN BROWN ADIPOSE TISSUE OF DEVELOPING RATS [PDF]
Josef P. Skála+2 more
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Ovarian cAMP and cGMP fluctuations in the hamster during the oestrous cycle [PDF]
C. J. Hubbard
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