Results 261 to 270 of about 148,798 (282)
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Molecular and Cellular Biochemistry, 2009
Production of cGMP in bacteria has been studied since the early 1970s. From the beginning on it proved to be a challenging topic. In Escherichia coli the cGMP levels were two orders of magnitude lower than the corresponding cAMP levels. Furthermore, no specific cGMP receptor protein was identified in the bacterium and a physiological role of cGMP in ...
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Production of cGMP in bacteria has been studied since the early 1970s. From the beginning on it proved to be a challenging topic. In Escherichia coli the cGMP levels were two orders of magnitude lower than the corresponding cAMP levels. Furthermore, no specific cGMP receptor protein was identified in the bacterium and a physiological role of cGMP in ...
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Cytotherapy, 1999
Over the past 20 years cell processing has changed. What an under statement! The types of cells processed, the complexity of the procedures, the addition of gene therapy and ex vivo cell expansion protocols together challenge the laboratory scientist.
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Over the past 20 years cell processing has changed. What an under statement! The types of cells processed, the complexity of the procedures, the addition of gene therapy and ex vivo cell expansion protocols together challenge the laboratory scientist.
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cGMP Signaling through cAMP- and cGMP-Dependent Protein Kinases
1995Publisher Summary The signaling pathways by which nitric oxide (NO) affects cell function, are by no means limited to the stimulation of guanylate cyclase. Concentrations of NO that activate guanylate cyclase may also have other effects on cells.
Thomas M. Lincoln +4 more
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2018
NO wird in Endothelzellen synthetisiert und aktiviert in glatten Muskelzellen die sGC, die den second messenger cGMP produziert. Die wichtigste Funktion von cGMP ist die Relaxation glatter Muskelzellen. cGMP wird uber die PDE5 abgebaut. Der NO-Donator GTN aktiviert die sGC und relaxiert Muskelzellen.
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NO wird in Endothelzellen synthetisiert und aktiviert in glatten Muskelzellen die sGC, die den second messenger cGMP produziert. Die wichtigste Funktion von cGMP ist die Relaxation glatter Muskelzellen. cGMP wird uber die PDE5 abgebaut. Der NO-Donator GTN aktiviert die sGC und relaxiert Muskelzellen.
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Nitric Oxide, 2018
The intracellular messenger molecule cGMP has an established function in the regulation of numerous physiological events. Yet for the identification of further biological cGMP-mediated functions, precise information whether a cGMP response exists in a certain cell type or tissue is mandatory. In this review, the techniques to measure cGMP i.e.
Michael Russwurm, Doris Koesling
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The intracellular messenger molecule cGMP has an established function in the regulation of numerous physiological events. Yet for the identification of further biological cGMP-mediated functions, precise information whether a cGMP response exists in a certain cell type or tissue is mandatory. In this review, the techniques to measure cGMP i.e.
Michael Russwurm, Doris Koesling
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Insights into cGMP signalling derived from cGMP kinase knockout mice
Frontiers in Bioscience, 2005cGMP signalling plays an important physiological role in diverse organs including the vasculature, the GI-tract and the nervous system. Furthermore, cGMP-elevating substances such as glyceryl trinitrate are important drugs used in cardiovascular diseases.
Franz Hofmann +2 more
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Roles of cGMP/cGMP-dependent protein kinase in platelet activation
Blood, 2004Within recent correspondence[1][1],[2][2] concerning the roles of cyclic guanosine monophosphate (cGMP)/cGMP–dependent protein kinase (cGK or PKG), Du et al[1][1](p4371) state that their data[3][3],[4][4] and ours[5][5] “clearly show that PKG inhibitors attenuate platelet aggregation induced ...
Stepan Gambaryan, Ulrich Walter
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cGMP and cGMP-Dependent Protein Kinase in Platelets and Blood Cells
2009Platelets are specialized adhesive cells that play a key role in normal and pathological hemostasis through their ability to rapidly adhere to subendothelial matrix proteins (platelet adhesion) and to other activated platelets (platelet aggregation). NO plays a crucial role in preventing platelet adhesion and aggregation.
Ulrich Walter, Stepan Gambaryan
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Nitric oxide synthase, cGMP, and NO‐mediated cGMP production in the olfactory bulb of the rat
The Journal of Comparative Neurology, 1996High levels of nitric oxide synthase and cyclic 3',5'-guanosine monophosphate (cGMP) in the olfactory bulb suggest that nitric oxide, acting as a diffusible intercellular messenger molecule inducing increased synthesis of cGMP, plays an important role in olfaction.
David A. Hopkins +3 more
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Natural behavior polymorphism due to a cGMP-dependent protein kinase of Drosophila.
Science, 1997Naturally occuring polymorphisms in behavior are difficult to map genetically and thus are refractory to molecular characterization. An exception is the foraging gene (for), a gene that has two naturally occurring variants in Drosophila melanogaster food-
Osborne Ka +9 more
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