Results 181 to 190 of about 48,956 (312)

Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications

Experimental Physiology, EarlyView.
Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó, Luis Eduardo M. Quintas   +1 more
wiley   +1 more source

Bifurcated projections from the trigeminal ganglion cells to the transverse sinus and infraorbital nerve in the rat: correlation with the oxytocin receptor and CGRP. [PDF]

J Headache Pain
Martínez-Lorenzana G, Córdova-Quiroga A, Condés-Lara M, González-Hernández A.   +3 more
europepmc   +1 more source

Rat Receptor-Activity-Modifying Proteins (RAMPs) for Adrenomedullin/CGRP Receptor: Cloning and Upregulation in Obstructive Nephropathy [PDF]

, 2000
Tetsuya Nagae, Masashi Mukoyama, Akira Sugawara, Kiyoshi Mori, Kensei Yahata, Masato Kasahara, Takayoshi Suganami, Hisashi Makino, Yuriko Fujinaga, Tetsuro Yoshioka, Issei Tanaka, Kazuwa Nakao   +11 more
openalex   +1 more source

Anatomical and functional mapping of vagal nociceptive sensory nerve subsets innervating the mouse lower airways by intersectional genetics

The Journal of Physiology, EarlyView.
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil, Justin Shane Hooper, Seol‐Hee Kim, Parmvir K. Bahia, Nika Pavelkova, Sanjay S. Nair, Teresa S. Darcey, Karina V. Lurye, Meghana Madaram, Jailene Fiallo, Stephen H. Hadley, Thomas E. Taylor‐Clark   +11 more
wiley   +1 more source

CGRP-dependent molecular signaling drives bone marrow stem cell osteogenesis in distraction osteogenesis. [PDF]

Front Bioeng Biotechnol
Hamiti Y, Liu K, Wang S, Yang X, Kadier X, Yusufu A.   +5 more
europepmc   +1 more source

Endogenous calcitonin gene‐related peptide (CGRP) mediates adrenergic‐dependent vasodilation induced by nicotine in mesenteric resistance arteries of the rat [PDF]

, 2000
Hinako Shiraki, Hiromu KAWASAKI, Satoko Tezuka, Akira Nakatsuma, Yuji Kurosaki   +4 more
openalex   +1 more source

Structural similarities reveal an expansive conotoxin family with a two‐finger toxin fold

Protein Science, Volume 34, Issue 11, November 2025.
Abstract Venomous animals have evolved a diverse repertoire of toxins with considerable pharmaceutical potential. The rapid evolution of peptide toxins, such as the conotoxins produced by venomous marine cone snails, often complicates efforts to infer their evolutionary relationships based solely on sequence information.
Muhammad Saad Khilji, Celeste M. Hackney, Thomas L. Koch, Arik J. Hone, Aymeric Rogalski, Maren Watkins, Jortan Tun, J. Michael McIntosh, Baldomero Olivera, Helena Safavi‐Hemami, Kaare Teilum, Lars Ellgaard   +11 more
wiley   +1 more source

Study of the Expression of Pain and Inflammation Pathway Genes and Their Associated miRNAs in Patients With Endometriosis. [PDF]

Biomed Res Int
Govahi A, Rokhgireh S, Arjmand F, Barati M, Ajdary M, Chaichian S, Mirgaloybayat S.   +6 more
europepmc   +1 more source

Regional Differences of CGRP-Immunoreactive Nerve Fibers in Nasal Epithelium of the Rat.

, 1995
Sang Hag Lee, Toshihiko Iwanaga, Osamu Hoshi, Isamu Adachi, Tsuneo Fujita   +4 more
openalex   +2 more sources

Transduction Mechanisms for Cold Temperature in Mouse Trigeminal and Vagal Ganglion Neurons Innervating Different Peripheral Organs

Acta Physiologica, Volume 241, Issue 11, November 2025.
ABSTRACT Aim To elucidate the molecular mechanism of cold sensing by visceral sensory endings, a side‐by‐side characterization of cold‐sensitive (CS) neurons in adult mouse trigeminal (TG) and vagal ganglia (VG) was performed. Methods A combination of physiological, pharmacological, molecular, and genetic tools was employed on trigeminal and vagal ...
Katharina Gers‐Barlag, Ana Gómez del Campo, Pablo Hernández‐Ortego, Eva Quintero, Félix Viana   +4 more
wiley   +1 more source