Results 221 to 230 of about 48,956 (312)

Pain Perception and Modulation: Fundamental Neurobiology and Recent Advances

European Journal of Neuroscience, Volume 62, Issue 8, October 2025.
Chronic pain is a major burden with variable treatment responses reflecting complex biopsychosocial and neurobiological factors. This narrative review synthesizes evidence on neural structures, circuits, and mediators involved in pain perception and modulation.
Willem W. J. van Strien, Markus W. Hollmann   +1 more
wiley   +1 more source

Super- and absolute responders to anti-cgrp monoclonal antibodies in migraine: A one-year multicenter, prospective, observational study. [PDF]

J Neurol
Barbanti P, Aurilia C, Fiorentini G, Egeo G, Mascarella D, Proietti S, Messina R, Filippi M, Bonassi S, Torelli P, Cevoli S, Italian Migraine Registry study group.   +11 more
europepmc   +1 more source

Estudo imunohistoquimico dos neuropeptideos CGRP, VIP e SP em tecido osseo saudavel e em tecido osseo da periodontite induzida por ligadura em ratos

, 1996
Henrique Guilherme de Castro Teixeira
openalex   +1 more source

The Spectrum of Headaches in Moyamoya Angiopathy: From Mechanisms to Management Strategies—A Consensus Review From the NEUROVASC Working Group

European Journal of Neurology, Volume 32, Issue 10, October 2025.
This article explores headache as a common yet underrecognized symptom of Moyamoya angiopathy (MMA), affecting up to 75% of patients. It reviews the potential pathophysiological mechanisms, including impaired autoregulation and microvascular ischemia, and discusses current and emerging treatment strategies, such as revascularization surgery and CGRP ...
Nicola Rifino, Anne Hege Aamodt, Markus Wiedmann, Markus Kramer, Jana Becker, Stéphanie Guey, Francesco Acerbi, Dominique Herve, Anna Bersano   +8 more
wiley   +1 more source

Pretreatment with an anti-CGRP monoclonal antibody attenuates mild TBI-induced tactile hypersensitivity in mice. [PDF]

J Headache Pain
Wattiez AS, Kuburas A, Castonguay WC, Fejgin K, Klewe IV, Russo AF.   +5 more
europepmc   +1 more source

Pharmacokinetics and safety of eptinezumab in children and adolescents with migraine

Headache: The Journal of Head and Face Pain, Volume 65, Issue 9, Page 1573-1583, October 2025.
Abstract Objective The primary objective was to characterize the pharmacokinetics (PK) and safety of eptinezumab in children and adolescents with migraine. Background Migraine in children and adolescents is a prevalent and potentially debilitating disease, and few preventive therapies are approved for use in these populations. Eptinezumab, a calcitonin
Andrew D. Hershey, Johan Areberg, Line Pickering Boserup, Annika Lindsten, Monika Rosen   +4 more
wiley   +1 more source

Reaction time and replenishment time of SP and CGRP after incision in rat skin

Open Life Sciences, 2014
Hochman Bernardo, Isoldi Felipe, Gonçalves de Freitas José, Lapin Guilherme, Quieregatto Paulo, Da Silva Erica, Chadi Gerson, Ferreira Lydia   +7 more
doaj   +1 more source

PACAP-38 in Cluster Headache: A Prospective, Case-Control Study of a Potential Treatment Target. [PDF]

Eur J Neurol
Søborg MK, Lund N, Snoer A, Barloese M, Jensen RH, Petersen AS.   +5 more
europepmc   +1 more source

Cgrp Release and Synergistic Interactions with Nitric Oxide: Implications for Pathogenesis of Septic Shock and the Vascular Problems of Diabetes Mellitus and Aging [PDF]

, 2001
Ronald R. Fiscus, X. Wang, Gabriel Hoi Huen Chan, Airong Ma, Sandra L. Chan   +4 more
openalex   +1 more source

Patient preferences for the preventive treatment of episodic migraine in the United States: A discrete‐choice experiment

Headache: The Journal of Head and Face Pain, Volume 65, Issue 9, Page 1541-1553, October 2025.
Abstract Objectives This study was conducted among participants with episodic migraine, to (i) assess patient preferences for attributes associated with calcitonin gene‐related peptide‐targeting therapies to prevent migraine and (ii) predict the probability that a real‐world patient would prefer an atogepant‐like treatment profile over monoclonal ...
Richard B. Lipton, Pranav Gandhi, Kelley Myers, Cooper Bussberg, Jonathan Stokes, Stephanie J. Nahas   +5 more
wiley   +1 more source