Results 71 to 80 of about 45,236 (268)
The Laryngoscope, EarlyView.This prospective pilot study aims to compare nasal mucosal sensitivity to air‐jet stimuli between ENS patients and patients who underwent septoplasty/turbinate reduction (septo‐turb) surgery, but without ENS symptoms. The ENS group had a significantly higher (less sensitive) threshold than the septo‐turb group for the septum opposing the center of the ...
Kanghyun Kim +8 more
wiley +1 more source
The Hidden Burden of Hemifacial Spasm: A Systematic Review of Non‐Motor Symptoms
Movement Disorders Clinical Practice, EarlyView.Abstract Background Hemifacial spasm (HFS) is a chronic neurological disorder characterized by involuntary contractions of facial muscles. Traditionally regarded as a motor condition, HFS encompasses a spectrum of non‐motor symptoms that are often overlooked but significantly affect patients’ quality of life.
Miriam Carvalho Soares +2 more
wiley +1 more source
Potassium channel activators protect the N-methyl-D-aspartate-induced cerebral vascular dilation after combined hypoxia and ischemia in piglets [PDF]
, 1998 Background and Purpose-Cerebral arteriolar dilation to N-methyl-D-aspartate (NMDA) is a neuronally mediated multistep process that is sensitive to cerebral hypoxia and ischemia (H/I).
Bari, Ferenc +2 more
core
Protein Transduction Method for Cerebrovascular Disorders [PDF]
, 2009 Many studies have shown that a motif of 11 consecutive arginines (11R) is one of the most effective protein transduction domains (PTD) for introducing proteins into the cell membrane.
Arimitsu, Seiji +9 more
core +1 more source
CGRP Receptor Antagonism and Migraine [PDF]
Neurotherapeutics, 2010 Calcitonin gene-related peptide (CGRP) is expressed throughout the central and peripheral nervous systems, consistent with control of vasodilatation, nociception, motor function, secretion, and olfaction. alphaCGRP is prominently localized in primary spinal afferent C and ADelta fibers of sensory ganglia, and betaCGRP is the main isoform in the enteric
Lars, Edvinsson, Tony W, Ho
openaire +2 more sources
Phytotherapy Research, EarlyView.Experimental workflow and main findings of the study. ABSTRACT Visceral pain is a major symptom of inflammatory bowel diseases (IBDs), requiring effective treatment strategies. Gut epithelium, beyond maintaining barrier integrity and microbiota homeostasis, modulates neurosensorial circuitries, influencing visceral sensitivity.
Francesco Margiotta +7 more
wiley +1 more source
Efficacy of fremanezumab in patients with chronic migraine and concomitant depression
Клинический разбор в общей медицинеBackground. Migraine is a common chronic disorder that ranks third in the disability-adjusted life years among nervous system disorders. It is well known that migraine is strongly associated with the depression/anxiety disorders; there is overwhelming ...
A.Y. Timokhovich +2 more
doaj +1 more source
Ubrogepant in the Acute Management of Migraine: A Narrative Review
Journal of Pain Research, 2021 Chia-Chun Chiang,1 Juliana H VanderPluym2 1Department of Neurology, Mayo Clinic, Rochester, MN, USA; 2Department of Neurology, Mayo Clinic, Scottsdale, AZ, USACorrespondence: Juliana H VanderPluym Email vanderpluym.juliana@mayo.eduAbstract: Ubrogepant is
Chiang CC, VanderPluym JH
doaj
Deficiency of Calcitonin Gene-Related Peptide Affects Macrophage Polarization in Osseointegration
Frontiers in Physiology, 2020 Macrophages have been described as a critical cell population regulating bone regeneration and osseointegration, and their polarization phenotype is of particular importance.
Ying Yuan +5 more
doaj +1 more source
Scientific Reports, 2021 This study aimed to explore the effect of calcitonin gene-related peptide (CGRP) on bladder smooth muscle cells (BSMCs) under high glucose (HG) treatment in vitro. BSMCs from Sprague–Dawley rat bladders were cultured and passaged in vitro.
Jun Xue +6 more
doaj +1 more source