Results 1 to 8 of about 11 (8)

CGSEA: A Flexible Tool for Evaluating the Associations of Chemicals with Complex Diseases

G3: Genes, Genomes, Genetics, 2020
The etiology of many human complex diseases or traits involves interactions between chemicals and genes that regulate important physiological processes.
Shiqiang Cheng, Mei Ma, Lu Zhang, Li Liu, Bolun Cheng, Xin Qi, Chujun Liang, Ping Li, Om Prakash Kafle, Yan Wen, Feng Zhang   +10 more
doaj   +2 more sources

Identification of candidate genes and chemicals associated with osteoarthritis by transcriptome-wide association study and chemical-gene interaction analysis

Arthritis Research & Therapy, 2023
Background Osteoarthritis (OA) is a common degenerative joint disease and causes chronic pain and disability to the elderly. Several risk factors are involved, such as aging, obesity, genetic susceptibility, and environmental factors.
Lin Mei, Zhiming Zhang, Ruiqi Chen, Zhongyue Liu, Xiaolei Ren, Zhihong Li   +5 more
doaj   +2 more sources

Identifying celiac disease-related chemicals by transcriptome-wide association study and chemical-gene interaction analyses

Frontiers in Genetics, 2022
Celiac disease (CeD) is one of the most common intestinal inflammatory diseases, and its incidence and prevalence have increased over time. CeD affects multiple organs and systems in the body, and environmental factors play a key role in its complex ...
Mengnan Lu, Ruoyang Feng, Yuesheng Liu, Yujie Qin, Hongyang Deng, Yanfeng Xiao, Chunyan Yin   +6 more
doaj   +1 more source

Identifying Environmental Endocrine Disruptors Associated With the Age at Menarche by Integrating a Transcriptome-Wide Association Study With Chemical-Gene-Interaction Analysis

Frontiers in Endocrinology, 2022
Menarche is the first occurrence of menstrual bleeding and one of the most important events of female puberty. Alarmingly, over the last several decades, the mean age at menarche (AAM) has decreased.
Mengnan Lu, Ruoyang Feng, Yujie Qin, Hongyang Deng, Biyao Lian, Chunyan Yin, Yanfeng Xiao   +6 more
doaj   +1 more source

Additional file 3 of Identification of candidate genes and pathways associated with juvenile idiopathic arthritis by integrative transcriptome-wide association studies and mRNA expression profiles

, 2023
Additional file 3:.
Lin Liu (74495), Peng Xu (17962), Mengnan Lu (12128694), Ruoyang Feng (12128697), Ke Xu (134879), Chunyan Yin (5384525)   +5 more
core   +1 more source

Table_1_Identifying Environmental Endocrine Disruptors Associated With the Age at Menarche by Integrating a Transcriptome-Wide Association Study With Chemical-Gene-Interaction Analysis.xlsx

, 2022
Menarche is the first occurrence of menstrual bleeding and one of the most important events of female puberty. Alarmingly, over the last several decades, the mean age at menarche (AAM) has decreased.
Mengnan Lu (12128694), Yujie Qin (12128700), Yanfeng Xiao (628673), Ruoyang Feng (12128697), Hongyang Deng (12128703), Chunyan Yin (5384525), Biyao Lian (12128706)   +6 more
core   +1 more source

Identifying chemicals associated with irritable bowel syndrome by integrating a transcriptome-wide association study with chemical-gene-interaction analysis.

PLoS ONE
BackgroundIrritable bowel syndrome (IBS) is a prominent functional gastrointestinal disorder, yet the precise causes and mechanisms behind it remain largely unclear.
Xinliang Zhao, Yang Yang, Zhigang Liu, Ruifang Sun, Aili Suo   +4 more
doaj   +1 more source

Trade promotion facilities in member and associate member in the Economic Commission for Asia and the Far East

, 1949
This publication provides an early post-World War II assessment of trade infrastructure and institutional mechanisms in the Asia-Pacific region. Here's a summary based on available historical context and references.
UN.ECAFE
core   +1 more source