Results 131 to 140 of about 342,040 (246)

Physician Disagreement With Guidelines as a Critical Barrier to Achieving LDL-C Targets in Very High-Risk Patients: An Implementation Science Study. [PDF]

open access: yesJ Korean Med Sci
Cho KH   +15 more
europepmc   +1 more source

Materiais e cores tradicionais nos centros históricos : caso de estudo no Quarteirão Chã, Porto

open access: yes, 2016
A seguinte dissertação pretende contribuir com uma proposta e uma metodologia de trabalho, para um planeamento da identidade visual dos centros históricos. Para isso utilizou-se como exemplo o Quarteirão Chã do centro histórico do Porto, local sugerido pelos professores da Unidade Curricular de Projeto III. Uma vez que, o Porto, é uma cidade onde a cor
openaire   +1 more source

KDM4A Erases the H3R17me2a Mark, Facilitating Chromosome Condensation

open access: yesAdvanced Science, EarlyView.
This study reveals a reversible histone modification switch governing chromosome condensation during mitosis. PKCα‐activated KDM4A removes H3R17me2a, permitting Suv39h1‐driven H3K9me3 deposition. This epigenetic transition recruits the chromosomal passenger complex and triggers Aurora B‐dependent H3S10 phosphorylation, coordinating chromatin remodeling
Yena Cho   +6 more
wiley   +1 more source

Effects of sialylated oligosaccharides on the N- and O-glycosylation of etanercept in recombinant CHO cells. [PDF]

open access: yesAppl Microbiol Biotechnol
Kim TH   +7 more
europepmc   +1 more source

Sulfakinin Signaling Sense Circulating Fructose and Suppresses Food Consumption via Insulin‐Like Peptide in Bactrocera Dorsalis

open access: yesAdvanced Science, EarlyView.
This study discovered a new pathway that tells fruit flies when to stop eating. It found that rising blood sugar (fructose) is detected by a sensor called GR43a. This triggers a chain reaction involving the satiety signal sulfakinin and its receptor, ultimately activating a final satiety signal, ILP5.
Hong‐Fei Li   +7 more
wiley   +1 more source

Developmentally Inspired, Mechanical–Metabolic Dual Gradient Osteochondral Constructs Bridging Regeneration and Therapeutic Screening

open access: yesAdvanced Science, EarlyView.
A developmentally inspired osteochondral construct integrates mechanical and metabolic dual gradients within a 3D‐printed platform. Human MSC spheroids are spatially directed to form cartilage–bone interfaces, enabling evaluation of regeneration without biochemical reagents and assessment of drug responses. This physiologically relevant, phase‐specific
Yurim Choi   +11 more
wiley   +1 more source

Stabilization of Single Metal Atoms on Graphitic Carbon Nitride: Synthetic Strategies and Emerging Applications

open access: yesAdvanced Science, EarlyView.
This review highlights recent advancements in stabilizing single metal atoms on graphitic carbon nitride emphasizing innovative synthesis strategies and emerging applications in electrocatalysis, photocatalysis and organic transformations, along with key challenges and future perspective. Abstract Emerging as a new frontier in catalysis science, single‐
Wenyao Zhang   +6 more
wiley   +1 more source

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