Results 81 to 90 of about 20,735 (212)

Quadriparesis with different diagnoses after COVID-19 vaccination: Case series and literature review

Journal of Family Medicine and Primary Care, 2023
Following vaccination with adenoviral vector-based ChAdOx1 nCoV-19, serious neurological adverse events have been reported. Here we report two cases who presented with quadriparesis following the adenoviral vector-based ChAdOx1 nCoV-19 vaccine. A 55-year-
Sachin Wali, Shreyas Gutte, Shubham Yadav, Mohan Gurjar, Vimal K. Paliwal, Vivek Singh, Afzal Azim, Banani Poddar   +7 more
doaj   +1 more source

Effect of Delta variant on viral burden and vaccine effectiveness against new SARS-CoV-2 infections in the UK [PDF]

, 2021
The effectiveness of the BNT162b2 and ChAdOx1 vaccines against new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections requires continuous re-evaluation, given the increasingly dominant B.1.617.2 (Delta) variant.
Bell, J, Cook, D, Crook, D, Diamond, I, Eyre, DW, Farrar, J, Hay, J, House, T, Matthews, PC, Newton, JN, Peto, TEA, Pouwels, KB, Pritchard, E, Rourke, E, Stoesser, N, Studley, R, Vihta, K-D, Walker, AS   +17 more
core  

HIV‐1 viral load and reservoir size remain stable following SARS‐CoV‐2 mRNA vaccination in people with HIV

HIV Medicine, EarlyView.
Abstract Background The potent immunogenicity of mRNA vaccination raised concerns about its impact on HIV‐1 viral load (VL) and reservoir size in people with HIV, which could drive vaccine hesitancy. As part of a prospective clinical trial, we investigated whether SARS‐CoV‐2 mRNA vaccination induced changes in VL and reservoir size after a 1‐year three‐
Oscar Kieri, Bianca B Jütte, Jan Vesterbacka, Soo Aleman, Hans‐Gustaf Ljunggren, Marcus Buggert, J Peter Svensson, Anders Sönnerborg, Piotr Nowak   +8 more
wiley   +1 more source

Understanding mechanisms of thrombosis and thrombocytopenia with adenoviral SARS-CoV-2 vaccines: a comprehensive synopsis

Efficacy and Mechanism Evaluation
Background Thrombosis with thrombocytopenia syndrome is a rare condition known to occur spontaneously or after heparin use. With the advent of COVID-19 vaccines during the pandemic, thrombosis with thrombocytopenia syndrome cases emerged post ...
Phillip LR Nicolson, Simon T Abrams, Gayatri Amirthalingam, Kevin Brown, Richard J Buka, Mark J Caulfield, Joshua Gardner, David Goldblatt, Charlotte Lovatt, Samantha J Montague, Dean J Naisbitt, Alan Parker, Sue Pavord, Mary E Ramsay, Jonathan AC Sterne, Cathie LM Sudlow, Cheng Hock Toh, Steve P Watson, Guozheng Wang, Angela M Wood, William Whiteley, Munir Pirmohamed   +21 more
doaj   +1 more source

ChAdOx1 nCoV-19 (AZD1222) vaccine candidate significantly reduces SARS-CoV-2 shedding in ferrets

npj Vaccines, 2021
Vaccines against SARS-CoV-2 are likely to be critical in the management of the ongoing pandemic. A number of candidates are in Phase III human clinical trials, including ChAdOx1 nCoV-19 (AZD1222), a replication-deficient chimpanzee adenovirus-vectored ...
Glenn A. Marsh, Alexander J. McAuley, Gough G. Au, Sarah Riddell, Daniel Layton, Nagendrakumar B. Singanallur, Rachel Layton, Jean Payne, Peter A. Durr, Hannah Bender, Jennifer A. Barr, John Bingham, Victoria Boyd, Sheree Brown, Matthew P. Bruce, Kathie Burkett, Teresa Eastwood, Sarah Edwards, Tamara Gough, Kim Halpin, Jenni Harper, Clare Holmes, William S. J. Horman, Petrus Jansen van Vuren, Suzanne Lowther, Kate Maynard, Kristen D. McAuley, Matthew J. Neave, Timothy Poole, Christina Rootes, Brenton Rowe, Elisha Soldani, Vittoria Stevens, Cameron R. Stewart, Willy W. Suen, Mary Tachedjian, Shawn Todd, Lee Trinidad, Duane Walter, Naomi Watson, Trevor W. Drew, Sarah C. Gilbert, Teresa Lambe, S. S. Vasan   +43 more
doaj   +1 more source

Resistance towards ChadOx1 nCoV-19 in an 83 Years Old Woman Experiencing Vaccine Induced Thrombosis with Thrombocytopenia Syndrome

Vaccines, 2022
Background: in this report, we describe the case of an 83-year-old woman vaccinated with ChadOx1 nCoV-19 who developed a so-called vaccine-induced thrombosis with thrombocytopenia syndrome and who did not develop any antibodies against the spike protein ...
Constant Gillot, Julien Favresse, Vincent Maloteau, Valérie Mathieux, Jean-Michel Dogné, François Mullier, Jonathan Douxfils   +6 more
doaj   +1 more source

Humoral immunogenicity and efficacy of a single dose of ChAdOx1 MERS vaccine candidate in dromedary camels [PDF]

, 2019
MERS-CoV seronegative and seropositive camels received a single intramuscular dose of ChAdOx1 MERS, a replication-deficient adenoviral vectored vaccine expressing MERS-CoV spike protein, with further groups receiving control vaccinations.
Abu-Obaidah, A, Albrahim, R, Aldibasi, OS, Aldowerij, A, Aldubaib, M, Alenazi, MW, Alhafufi, A, Alharbi, NK, Aljami, HA, Alkarar, A, Almansour, A, Almasoud, A, Azhar, E, Balkhy, HH, Bayoumi, F, Becker, S, Gilbert, Sarah, Hashem, AM, Ibrahim, OH, Kasem, S, Kupke, A, Lambe, Teresa, Qasim, I, Temperton, NJ, Yoon, I-K   +24 more
core   +2 more sources

Life Course Malaria Exposure and SARS‐CoV‐2 Seroepidemiology in Ugandan Adolescents: A Longitudinal Study Nested in a Birth Cohort

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background COVID‐19 has had major global health impacts, yet reported morbidity and mortality have been lower in Africa despite serological evidence of widespread infection. Malaria has been proposed as a potential modifier of susceptibility to and outcomes of SARS‐CoV‐2 infection.
Ludoviko Zirimenya, Doreen Nayebare, Claire Baine, Jacent Nassuuna, Milly Namutebi, Christopher Zziwa, Denis Nsubuga, Fred Kiwudhu, Florence Akello, Josephine Tumusiime, Gloria Oduru, Grace Kabami, Hellen Akurut, Rachel Nakyesige, Agnes Natukunda, Anne Wajja, Lawrence Lubyayi, Simon Kimuda, Gyaviira Nkurunungi, Jennifer Serwanga, Katie J. Doores, Emily L. Webb, Alison M. Elliott   +22 more
wiley   +1 more source

Heterologous ChAdOx1-BNT162b2 vaccination in Korean cohort induces robust immune and antibody responses that includes Omicron

iScience, 2022
Summary: Heterologous ChAdOx1-BNT162b2 vaccination induces a stronger immune response than BNT162b2-BNT162b2. Here, we investigated the molecular transcriptome, germline allelic variants of immunoglobulin loci, and anti-Omicron antibody levels in 46 ...
Hye Kyung Lee, Jinyoung Go, Heungsup Sung, Seong Who Kim, Mary Walter, Ludwig Knabl, Priscilla A. Furth, Lothar Hennighausen, Jin Won Huh   +8 more
doaj   +1 more source

Kapiti plains ranch: Farmhouse and research centre [PDF]

, 2017
Wellcome ...
International Livestock Research Institute
core   +1 more source