Results 41 to 50 of about 35,461 (210)

Chagas' Heart Disease [PDF]

Clinical Cardiology, 2000
AbstractChagas' disease is caused by a protozoan parasite, Trypanosoma cruzi, that is transmitted to humans through the feces of infected bloodsucking insects in endemic areas of Latin America, or occasionally by nonvectorial mechanisms, such as blood transfusion.
A, Rassi, A, Rassi, W C, Little
openaire   +2 more sources

Analysis of Gene Expression in Aedes aegypti Suggests Changes in Early Genetic Control of Mosquito Development

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos, Danielle Santos, Lupis Ribeiro, Jonathan J. Mucherino‐Muñoz, Marcelle Uhl, Carlos Logullo, A. Mendonça‐Amarante, M. Fantappie, Rodrigo Nunes‐da‐Fonseca   +8 more
wiley   +1 more source

Elimination of Chagas disease transmission: perspectives

Memorias do Instituto Oswaldo Cruz, 2009
One hundred years after its discovery by Carlos Chagas, American trypanosomiasis, or Chagas disease, remains an epidemiologic challenge. Neither a vaccine nor an ideal specific treatment is available for most chronic cases.
João Carlos Pinto Dias
doaj   +1 more source

Chagas disease in Canadian blood donors: 15 years of selective testing. [PDF]

Vox Sang
Abstract Background and Objectives Chagas disease (Trypanosoma cruzi), prevalent in Mexico, Central and South America, can be transfusion‐transmitted. Selective serological testing of blood donors was implemented over 15 years ago. We describe the trends in infections and characteristics of donors selected for testing.
O'Brien SF, Goldman M, Lewin A, Uzicanin S, Fan W, Drews SJ.   +5 more
europepmc   +2 more sources

Exometabolomics Reveals Metabolic Modulation Induced by Chia Oil Supplementation in Adipose Tissue Explants From Obese Mice

Lipids, EarlyView.
The experimental design and the exometabolomic findings obtained by 1H‐NMR analysis of conditioned media from subcutaneous (SAT) and epididymal adipose tissue (EAT) explants of control and obese mice supplemented with chia oil (1.5% (w/w)). Following 8 weeks of control or high‐fat diet and 5 weeks of chia oil supplementation, SAT and EAT explants were ...
Gilson Costa dos Santos Jr, Agatha Assis‐Ferreira, Gabrielly Muniz‐Cassuce, Tatiana El Bacha, Christina Barja‐Fidalgo, Simone Vargas da Silva   +5 more
wiley   +1 more source

Immunopathology of Chagas disease [PDF]

Memórias do Instituto Oswaldo Cruz, 1999
The main clinical forms of Chagas disease (acute, indeterminate and chronic cardiac) present strong evidences for the participation of the immune system on pathogenesis. Although parasite multiplication is evident during acute infection, the intense acute myocarditis of this phase exhibits clear ultrastructural signs of cell-mediated immune damage ...
openaire   +4 more sources

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Assessment of the Performance of Indirect Immunofluorescence Assay for Chagas Disease in Dogs Using a Reference Panel of Four Chimeric Proteins. [PDF]

Vet Med Sci
We evaluated the performance of an indirect immunofluorescence (IIF) assay for detecting anti‐Trypanosoma cruzi IgG in dogs using four chimeric IBMP antigens and latent class analysis. The IIF assay showed suboptimal sensitivity and overall accuracy compared to ELISA and LCA‐based methods.
Silva ÂAO, Costa TF, Fontes ND, Santos EF, Rocha AVVO, Miranda LM, Almeida-Souza F, Costa FB, Nogueira RMS, Sampaio DD, Celedon PAF, Zanchin NIT, Costa APD, Santos FLN.   +13 more
europepmc   +2 more sources

Chagas disease in prehistory

Anais da Academia Brasileira de Ciências, 2011
The classical hypothesis proposes that Chagas disease has been originated in the Andean region among prehistoric people when they started domesticating animals, changing to sedentary habits, and adopting agriculture. These changes in their way of life happened nearly 6,000 years ago.
Ferreira, Luiz F., Jansen, Ana M., Araújo, Adauto   +2 more
openaire   +6 more sources

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

Phytotherapy Research, EarlyView.
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley   +1 more source