Results 41 to 50 of about 53,221 (243)

Chagas' heart disease [PDF]

open access: yesArquivos Brasileiros de Cardiologia, 1999
Chagas’ disease is a protozoan infection caused by Trypanosoma cruzi and is mainly acquired by vectorial transmission in endemic areas, when infected excreta of Triatominae bugs are inoculated into the sting site or neighbouring mucous membranes of the victim.
Marin-Neto, José Antonio   +2 more
openaire   +5 more sources

Research needs for Chagas disease prevention.

open access: yes, 2010
We present an overview of the two main strategies for the primary (vector control) and secondary (patient care) prevention of Chagas disease (CD). We identify major advances, knowledge gaps, and key research needs in both areas.
Santos, Walter S   +3 more
core   +1 more source

Population movements, borders, and Chagas disease [PDF]

open access: yes, 2021
Currently, Chagas disease is a complex global health problem with local and global implications. In the present article, we approach this complexity from the perspective of human mobility and its effects on people?s health in places of origin and in ...
Ventura Garcia, Laia   +5 more
core   +1 more source

Effect of an exercise-based cardiac rehabilitation program on quality of life of patients with chronic Chagas cardiomyopathy: results from the PEACH randomized clinical trial

open access: yesScientific Reports
To investigate the effect of an exercise-based cardiac rehabilitation program on the quality of life (QoL) of patients with chronic Chagas cardiomyopathy (CCC).
Marcelo Carvalho Vieira   +15 more
doaj   +1 more source

Duration of COVID-19 symptoms in children: a longitudinal study in a Rio de Janeiro favela, Brazil

open access: yesBMJ Open
Objectives COVID-19 in children is generally of short duration, but some may take longer to recover. This study investigated the time to symptom resolution following SARS-CoV-2 infection among children in a community setting on the outskirts of an urban ...
Patrícia Brasil   +10 more
doaj   +1 more source

Paleopathology of a putative colossosaurian caudal vertebra (Neosauropoda: Titanosauria) from the Presidente Prudente Formation, Brazil

open access: yesThe Anatomical Record, EarlyView.
Abstract Studies investigating paleopathologies in sauropods remain scarce despite their relative abundance in the fossil record. In this study we report new occurrence of paleopathological features, corresponding to a neoplasm found in a middle caudal vertebra (MCT.R.2120) of an advanced titanosaur from the Presidente Prudente Formation (Bauru Basin ...
Maria Luiza Peres Bertolossi   +5 more
wiley   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva   +8 more
wiley   +1 more source

CrAg screening strategy reduces definitive sequelae in people living with HIV

open access: yesDiscover Viruses
Background Screenning cryptococcal antigen (CrAg) of people living with HIV (PLHIV) reduces the morbidity and development of cryptococcal meningitis, but recent publications shows that it does not reduce mortality when comparable with a negative CrAg ...
Marcela de Faria Ferreira   +4 more
doaj   +1 more source

Was Chagas disease responsible for Darwin’s illness? The overlooked eco-epidemiological context in Chile

open access: yesRevista Chilena de Historia Natural, 2021
The source of Darwin’s illness has been a contentious issue in the literature for almost 70 years. Different causal factors have been invoked to account for his symptoms, including Chagas disease.
Carezza Botto-Mahan, Rodrigo Medel
doaj   +1 more source

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra   +8 more
wiley   +1 more source

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