Results 21 to 30 of about 35,461 (210)

Current situation and perspectives regarding human Chagas disease in midwestern of the state of Minas Gerais, Brazil

open access: yesMemorias do Instituto Oswaldo Cruz, 2014
Recognising the importance of Chagas disease in Brazil, Bambuí set up epidemiological surveillance for Chagas disease in 1974 and was the first municipality to do so.
Christiane Santos Matos   +4 more
doaj   +1 more source

American trypanosomiasis and Chagas disease: Sexual transmission

open access: yesInternational Journal of Infectious Diseases, 2019
Objective: To contribute to the discussion on the research findings indicating the sexual transmission of American trypanosomiasis and Chagas disease in humans.
Clever Gomes   +4 more
doaj   +1 more source

Chagas Disease in Europe

open access: yesTropical Medicine and Infectious Disease, 2023
Chagas disease is currently present in many non-endemic countries and remains a neglected tropical disease globally. A review of the literature identified significant gaps and scarcity of updated information from European countries, with most studies reporting data from Spain and Italy.
Marta Gonzalez-Sanz   +5 more
openaire   +3 more sources

Effect of an exercise-based cardiac rehabilitation program on quality of life of patients with chronic Chagas cardiomyopathy: results from the PEACH randomized clinical trial

open access: yesScientific Reports
To investigate the effect of an exercise-based cardiac rehabilitation program on the quality of life (QoL) of patients with chronic Chagas cardiomyopathy (CCC).
Marcelo Carvalho Vieira   +15 more
doaj   +1 more source

Duration of COVID-19 symptoms in children: a longitudinal study in a Rio de Janeiro favela, Brazil

open access: yesBMJ Open
Objectives COVID-19 in children is generally of short duration, but some may take longer to recover. This study investigated the time to symptom resolution following SARS-CoV-2 infection among children in a community setting on the outskirts of an urban ...
Patrícia Brasil   +10 more
doaj   +1 more source

Paleopathology of a putative colossosaurian caudal vertebra (Neosauropoda: Titanosauria) from the Presidente Prudente Formation, Brazil

open access: yesThe Anatomical Record, EarlyView.
Abstract Studies investigating paleopathologies in sauropods remain scarce despite their relative abundance in the fossil record. In this study we report new occurrence of paleopathological features, corresponding to a neoplasm found in a middle caudal vertebra (MCT.R.2120) of an advanced titanosaur from the Presidente Prudente Formation (Bauru Basin ...
Maria Luiza Peres Bertolossi   +5 more
wiley   +1 more source

Chagas Disease and Heart Failure: An Expanding Issue Worldwide

open access: yesEuropean Cardiology Review, 2019
Chagas disease, originally a South American endemic health problem, is expanding worldwide because of people migration. Its main impact is on the cardiovascular system, producing myocardial damage that frequently results in heart failure.
Felipe Martinez   +3 more
doaj   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva   +8 more
wiley   +1 more source

Was Chagas disease responsible for Darwin’s illness? The overlooked eco-epidemiological context in Chile

open access: yesRevista Chilena de Historia Natural, 2021
The source of Darwin’s illness has been a contentious issue in the literature for almost 70 years. Different causal factors have been invoked to account for his symptoms, including Chagas disease.
Carezza Botto-Mahan, Rodrigo Medel
doaj   +1 more source

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra   +8 more
wiley   +1 more source

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