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Chagas disease [PDF]

open access: yesPostgraduate Medical Journal, 2006
Abstract Chagas disease is the clinical condition triggered by infection with the protozoan Trypanosoma cruzi. The infection is transmitted by triatomine insects while blood feeding on a human host. Field studies predict that one third of an estimated 18 million T cruzi-infected humans in Latin America will die of Chagas disease.
A R L, Teixeira   +4 more
openaire   +2 more sources

Longitudinal study of patients with chronic Chagas cardiomyopathy in Brazil (SaMi-Trop project): a cohort profile. [PDF]

open access: yes, 2016
PurposeWe have established a prospective cohort of 1959 patients with chronic Chagas cardiomyopathy to evaluate if a clinical prediction rule based on ECG, brain natriuretic peptide (BNP) levels, and other biomarkers can be useful in clinical practice ...
Bierrenbach, Ana Luiza   +10 more
core   +3 more sources

Integrated control of chagas disease for its elimination as public health problem: A review [PDF]

open access: yes, 2015
Chagas disease or American trypanosomiasis is, together with geohelminths, the neglected disease that causes more loss of years of healthy life due to disability in Latin America.
Segura, Elsa Leonor   +1 more
core   +4 more sources

Key Chagas disease missing knowledge among at-risk population in Spain affecting diagnosis and treatment

open access: yesInfectious Diseases of Poverty, 2021
Background Chagas disease is endemic in Latin America and, over the last few decades, due to population movements, the disease has spread to other continents. Early diagnosis and treatment are critical in terms of improving outcomes for those living with
María Romay-Barja   +4 more
doaj   +1 more source

Congenital Chagas Disease in the United States: Cost Savings Through Maternal Screening [PDF]

open access: yes, 2018
Chagas disease, caused by Trypanosoma cruzi, is transmitted by insect vectors through transfusions, transplants, insect feces in food, and from mother to child during gestation.
Bialek, Stephanie R.   +3 more
core   +2 more sources

A protocol update for the Selenium Treatment and Chagasic Cardiomyopathy (STCC) trial

open access: yesTrials, 2018
Several studies evaluating clinical forms of chronic Chagas disease show that about one-third of patients present cardiac involvement. Heart failure, sudden death and cardioembolic stroke are the main mechanisms of death in Chagas heart disease.
Marcelo Teixeira Holanda   +24 more
doaj   +1 more source

External Quality Assessment as a strategy for Chagas disease surveillance: a study in four municipalities of Pernambuco. [PDF]

open access: diamondRev Soc Bras Med Trop
Soares ENL   +6 more
europepmc   +2 more sources

Novel cruzain inhibitors for the treatment of Chagas' disease. [PDF]

open access: yes, 2012
The protozoan parasite Trypanosoma cruzi, the etiological agent of Chagas' disease, affects millions of individuals and continues to be an important global health concern.
Arkin, Michelle R   +6 more
core   +1 more source

Systemic antibiotics for preventing ventilator-associated pneumonia in comatose patients: a systematic review and meta-analysis

open access: yesAnnals of Intensive Care, 2017
Background Early-onset ventilator-associated pneumonia (EO-VAP) is the leading cause of morbidity and mortality in comatose patients. However, VAP prevention bundles focus mainly on late-onset VAP and may be less effective in preventing EO-VAP in ...
Cássia Righy   +4 more
doaj   +1 more source

Current knowledge of Chagas-related heart disease among pediatric cardiologists in the United States

open access: yesBMC Cardiovascular Disorders, 2021
Background Chagas disease is a pathogenic parasitic infection with approximately 8 million cases worldwide and greater than 300,000 cases in the United States (U.S.).
Sanchi Malhotra   +4 more
doaj   +1 more source

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