Results 1 to 10 of about 5,526 (135)

Circulating microRNAs as biomarkers of Chagas cardiomyopathy [PDF]

Frontiers in Cardiovascular Medicine, 2023
BackgroundChagas cardiomyopathy (CHCM) is the most important clinical manifestation of Chagas disease. The analysis of cardiac miRNAs may contribute to predicting the progression to CHCM in Chagas indeterminate phase and/or to the differential diagnosis ...
Laura Antonietti, Laura Antonietti, Javier Mariani, Javier Mariani, María Jose Martínez, Manuela Santalla, Natalia Vensentini, Diego Alfredo Kyle, Maximiliano de Abreu, Maximiliano de Abreu, Carlos Tajer, Carlos Tajer, Ezequiel Lacunza, Paola Ferrero   +13 more
doaj   +2 more sources

Electro-Mechanical Dissociation in Chagas Cardiomyopathy: Comparative Analysis of Arrhythmic Burden Beyond LVEF. [PDF]

J Arrhythm
Despite matched clinical characteristics and LVEF, patients with Chagas cardiomyopathy exhibit a significantly higher arrhythmic burden compared to ischemic cardiomyopathy. This electro‐mechanical dissociation highlights the necessity of sudden death risk stratification strategies that extend beyond traditional ejection fraction thresholds.
Echeverría LE, Rojas LZ, Serrano-García AY, Ariza YT, Luengas C, Marcus R, Morillo CA, Gómez-Ochoa SA.   +7 more
europepmc   +2 more sources

Echocardiographic predictors of mortality in heart failure from Chagas cardiomyopathy: Refining risk stratification with speckle-tracking echocardiography [PDF]

American Heart Journal Plus
Background: Chagas cardiomyopathy is a major cause of mortality in endemic regions, predicted primarily by left ventricular (LV) systolic function. Speckle-tracking echocardiography (STE)–derived strain is a sensitive tool for assessing ventricular ...
Marcelo Alves Maia, Ester Cerdeira Sabino, Jose Luiz Padilha da Silva, Cesar Augusto Taconeli, Lea Campos de Oliveira, Omar Ribeiro Santos Junior, Ana Isabel Nobre Maia, Fellipe Colares P.G. Versiani, Ariela Mota Ferreira, Antonio Luiz P. Ribeiro, Maria Carmo P. Nunes   +10 more
doaj   +2 more sources

Stroke in Chagas disease: from pathophysiology to clinical practice [PDF]

Revista da Sociedade Brasileira de Medicina Tropical, 2022
Despite substantial progress toward its control, Chagas disease continues to be a major public health problem in Latin America and has become a global health concern.
Thaís Aparecida Reis Lage, Julia Teixeira Tupinambás, Lucas Bretas de Pádua, Matheus de Oliveira Ferreira, Amanda Cambraia Ferreira, Antonio Lucio Teixeira, Maria Carmo Pereira Nunes   +6 more
doaj   +1 more source

Determinants of minute ventilation-carbon dioxide production relationship in Chagas cardiomyopathy

Revista da Sociedade Brasileira de Medicina Tropical, 2021
INTRODUCTION: The minute ventilation-carbon dioxide production relationship (VE/VCO2 slope) is among the main prognostic factors of Chagas cardiomyopathy whose determinants remain unknown. METHODS: Seventy-eight patients with Chagas cardiomyopathy were
Lucas Frois Fernandes Oliveira, Janaina Martins Andrade, Pedro Henrique Scheidt Figueiredo, Matheus Ribeiro Ávila, Whesley Tanor Silva, Marcus Vinicius Accetta Vianna, Renato Guilherme Trede Filho, Henrique Silveira Costa, Manoel Otávio Costa Rocha, Vanessa Pereira Lima   +9 more
doaj   +1 more source

Sustained monomorphic ventricular tachycardia as the presenting sign of Chagas’ cardiomyopathy in a low prevalence setting, diagnosis and management challenges. A case report

Therapeutic Advances in Infectious Disease, 2022
Approximately 300,000 people in the United States are estimated to have Chagas’ disease, with cardiac manifestations including arrhythmias occurring in 20%–30% of patients.
Devang R. Amin, Sean Behan, Michelle Pengshung, Amber Khanna, Wendy S. Tzou, Nicholas Mantini, Andrés F. Henao-Martinez, Alexis Tumolo, Daniel W. Groves   +8 more
doaj   +1 more source

Deficient regulatory T cell activity and low frequency of IL-17-producing T cells correlate with the extent of cardiomyopathy in human Chagas' disease. [PDF]

PLoS Neglected Tropical Diseases, 2012
BACKGROUND: Myocardium damage during Chagas' disease results from the immunological imbalance between pro- and production of anti-inflammatory cytokines and has been explained based on the Th1-Th2 dichotomy and regulatory T cell activity.
Paulo Marcos Matta Guedes, Fredy Roberto Salazar Gutierrez, Grace Kelly Silva, Renata Dellalibera-Joviliano, Gerson Jhonatan Rodrigues, Lusiane Maria Bendhack, Anis Rassi, Anis Rassi, André Schmidt, Benedito Carlos Maciel, José Antonio Marin Neto, João Santana Silva   +11 more
doaj   +1 more source

Stroke correlates in chagasic and non-chagasic cardiomyopathies. [PDF]

PLoS ONE, 2012
BACKGROUND: Aging and migration have brought changes to the epidemiology and stroke has been shown to be independently associated with Chagas disease.
José Alberto Martins da Matta, Roque Aras, Cristiano Ricardo Bastos de Macedo, Cristiano Gonçalves da Cruz, Eduardo Martins Netto   +4 more
doaj   +1 more source

Association of left ventricular abnormalities with incident cerebrovascular events and sources of thromboembolism in patients with chronic Chagas cardiomyopathy

Journal of Cardiovascular Magnetic Resonance, 2022
Background Although Chagas cardiomyopathy is related to thromboembolic stroke, data on risk factors for cerebrovascular events in Chagas disease is limited.
Henrique Turin Moreira, Gustavo Jardim Volpe, Gustavo Marques Mesquita, Maria Fernanda Braggion-Santos, Antonio Pazin-Filho, José Antonio Marin-Neto, André Schmidt   +6 more
doaj   +1 more source

Antiparasitic treatment with itraconazole and amiodarone in 2 dogs with severe, symptomatic Chagas cardiomyopathy

Journal of Veterinary Internal Medicine, 2022
Chagas cardiomyopathy, caused by the protozoal parasite Trypanosoma cruzi, is characterized by arrhythmias, myocardial damage, heart failure, and sudden death.
Elizabeth L. Malcolm, Ashley B. Saunders, Jordan P. Vitt, Bruno G. Boutet, Sarah A. Hamer   +4 more
doaj   +1 more source