Results 31 to 40 of about 178,801 (195)

Scientometrics analysis of research activity and collaboration patterns in Chagas cardiomyopathy. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2018
Chagas cardiomyopathy is a serious and common complication of Chagas disease.Through bibliometric and Social Network Analysis, we examined patterns of research on Chagas cardiomyopathy, identifying the main countries, authors, research clusters, and ...
Gregorio González-Alcaide   +2 more
doaj   +1 more source

CD14 genotype and functional dichotomy of CD14+ and CD14- cells are associated with activated immune response and development of Chagas dilated cardiomyopathy [PDF]

open access: yesMemorias do Instituto Oswaldo Cruz
We aimed to investigate the association of CD14 -260C/T (rs2569190) polymorphism and Chagas cardiomyopathy and the functional characteristics of CD14+ and CD14- monocytes upon infection with Trypanosoma cruzi.
Germano Carneiro Costa   +7 more
doaj   +2 more sources

Developments in the management of Chagas cardiomyopathy [PDF]

open access: yesExpert Review of Cardiovascular Therapy, 2015
Over 100 years have elapsed since the discovery of Chagas disease and there is still much to learn regarding pathogenesis and treatment. Although there are antiparasitic drugs available, such as benznidazole and nifurtimox, they are not totally reliable and often toxic.
Herbert B, Tanowitz   +10 more
openaire   +2 more sources

Data associated with: Chagas cardiomyopathy cohort in Bolivia

open access: yes, 2023
This includes general recruitment data (age,sex, dates of interviews and tests), medical history answers, medications, ekg results and echo results for patients in the chagas cardiomyopathy ...
Gilman, Robert
core   +1 more source

Comprehensive analysis of three TYK2 gene variants in the susceptibility to Chagas disease infection and cardiomyopathy.

open access: yesPLoS ONE, 2018
Tyrosine kinase 2 (TYK2) is a member of the Janus kinases family implicated in the signal transduction of type I interferons and several interleukins. It has been described that genetic mutations within TYK2 lead to multiple deleterious effects in the ...
Daniel A Leon Rodriguez   +7 more
doaj   +1 more source

Increases in [IP3]i aggravates diastolic [Ca2+] and contractile dysfunction in Chagas' human cardiomyocytes.

open access: yesPLoS Neglected Tropical Diseases, 2020
Chagas cardiomyopathy is the most severe manifestation of human Chagas disease and represents the major cause of morbidity and mortality in Latin America.
Alfredo Mijares   +3 more
doaj   +1 more source

Chagas disease and systemic autoimmune diseases among Bolivian patients in Switzerland

open access: yesMemorias do Instituto Oswaldo Cruz, 2018
BACKGROUND Chronic cardiomyopathy occurs in 20-40% of the patients with Chagas disease. Autoimmune mechanisms may contribute to its pathogenesis. We diagnosed several cases of systemic autoimmune diseases among Bolivian migrants in Geneva with a high ...
Yves Jackson   +4 more
doaj   +1 more source

Chronic Chagas cardiomyopathy: a review of the main pathogenic mechanisms and the efficacy of aetiological treatment following the BENznidazole Evaluation for Interrupting Trypanosomiasis (BENEFIT) trial

open access: yesMemorias do Instituto Oswaldo Cruz
Chagas cardiomyopathy is the most frequent and most severe manifestation of chronic Chagas disease, and is one of the leading causes of morbidity and death in Latin America.
Anis Rassi Jr   +2 more
doaj   +1 more source

Clinical parameters, parasite genetics and cardiovascular risk factors present in 175 patients with Chronic Chagas Cardiomyopathy.

open access: yes, 2022
Clinical parameters, parasite genetics and cardiovascular risk factors present in 175 patients with Chronic Chagas Cardiomyopathy.
João Santana da Silva (8474322)   +7 more
core   +1 more source

Ventricular speckle tracking strain of patients with Chagas cardiomyopathy compared to idiopathic cardiomyopathy.

open access: yes, 2019
Ventricular speckle tracking strain of patients with Chagas cardiomyopathy compared to idiopathic cardiomyopathy.
Manoel Otávio da Costa Rocha (7300247)   +9 more
core   +1 more source

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