Results 31 to 40 of about 707 (123)

Long-term Survival Following Heart Transplantation for Chagas Versus Non-Chagas Cardiomyopathy: A Single-center Experience in Northeastern Brazil Over 2 Decades

Transplantation Direct, 2022
Background. Data on post–heart transplant (HT) survival of patients with Chagas cardiomyopathy (CC) are scarce. We sought to evaluate post-HT survival in patients with CC as compared with other causes of heart failure across different eras of HT. Methods.
Jefferson L. Vieira, MD, MBA, PhD, Maria G. V. Sobral, RN, Francisco Y. Macedo, MD, PhD, Raquel S. Florêncio, RN, Germana P. L. Almeida, MD, Glauber G. Vasconcelos, MD, Juliana R. Fernandes, MD, Laura L. E. Marinho, MD, Daniel F. M. Trompieri, MD, Tilak K. R. Pasala, MD, Juan A. C. Mejia, MD, João D. Souza-Neto, MD, PhD   +11 more
doaj   +1 more source

Biomarkers and Mortality in Severe Chagas Cardiomyopathy [PDF]

Global Heart, 2015
Chagas cardiomyopathy is a chronic sequela of infection by the parasite, Trypanosoma cruzi. Advanced cardiomyopathy is associated with a high mortality rate, and clinical characteristics have been used to predict mortality risk. Though multiple biomarkers have been associated with Chagas cardiomyopathy, it is unknown how these are related to survival ...
Sherbuk, Jacqueline E., Okamoto, Emi E., Marks, Morgan A., Fortuny, Enzo, Clark, Eva H., Galdos-Cardenas, Gerson, Vasquez-Villar, Angel, Fernandez, Antonio B., Crawford, Thomas C., Do, Rose Q., Flores-Franco, Jorge Luis, Colanzi, Rony, Gilman, Robert H., Bern, Caryn   +13 more
openaire   +3 more sources

Anticancer and Cardioprotective Properties of Medicinal Mushrooms: Current Evidence and Future Prospects

New Zealand Journal of Botany, Volume 64, Issue 3, September 2026.
Introduction: Cardiotoxicity is an undesirable side effect of chemotherapy that limits the effectiveness of cancer treatment. Almost all cardiotoxic agents cause cardiovascular complications, leading to oxidative stress and other pathological conditions.
Susanna Badalyan, Sylvie Rapior, Anush Barkhudaryan   +2 more
wiley   +1 more source

Duration‐Dependent Cardiac Effects of Anabolic‐Androgenic Steroid Use in Strength‐Trained Athletes: A Systematic Review and Meta‐Analysis

Echocardiography, Volume 43, Issue 9, September 2026.
Anabolic‐androgenic steroid use is associated with cardiac structural remodeling and functional impairment in strength‐trained athletes. Longer exposure was significantly associated with greater reductions in LVEF and increases in LVMI and posterior wall thickness, while other echocardiographic abnormalities showed heterogeneous temporal patterns ...
Matheus de Medeiros Fernandes, Pedro Gomes Batista, Camila Viviane Ribera Chagas, Railla Raquel Albino dos Santos Silva, Fernanda Medeiros Santos, Miguel Chaves Lenzi, Felipe de Medeiros Fernandes, Ranna Santos Pessoa, Patrícia Jovelina de Freitas, Flávio Henrique Amaral Pires Véras, Stephan Barisic Junior, Douglas Nunes Cavalcante, Juliana Giorgi, Caroline Fischer‐Bacca   +13 more
wiley   +1 more source

Left Atrial Coupling Indexes as New Mortality Predictors in Chronic Chagas Disease

Echocardiography, Volume 43, Issue 8, August 2026.
Echocardiographic left atrial coupling indexes are promising prognostic markers of dismal outcome in Chagas disease. They were associated with all‐cause mortality independent from age, sex, and echocardiographic indexes, including LV ejection fraction, supporting their potential clinical relevance.
Roberto M. Saraiva, Mauro Felippe F. Mediano, Henrique H. Veloso, Marcelo T. Holanda, Andréa R. Costa   +4 more
wiley   +1 more source

Omega-3 supplementation on inflammatory markers in patients with chronic Chagas cardiomyopathy: a randomized clinical study

Nutrition Journal, 2017
Background Several studies have been focusing on the effect of omega-3 polyunsaturated fatty acids on modulation of inflammatory markers in several cardiopathies.
Paula Simplício da Silva, Mauro Felippe Felix Mediano, Gilberto Marcelo Sperandio da Silva, Patricia Dias de Brito, Claudia Santos de Aguiar Cardoso, Cristiane Fonseca de Almeida, Luiz Henrique Conde Sangenis, Roberta Olmo Pinheiro, Alejandro Marcel Hasslocher-Moreno, Pedro Emmanuel Alvarenga Americano do Brasil, Andrea Silvestre de Sousa   +10 more
doaj   +1 more source

A cardiac rehabilitation exercise program potentially inhibits progressive inflammation in patients with severe Chagas cardiomyopathy: A pilot single-arm clinical trial

Journal of Research in Medical Sciences, 2020
Background: Cardiac rehabilitation exerts anti-inflammatory effect on several cardiovascular diseases; however, these effects were not described for Chagas cardiomyopathy, which is associated with pro-inflammatory imbalance.
Luiz Fernando Rodrigues Junior, Fernanda de Souza Nogueira Sardinha Mendes, Vivian Liane Mattos Pinto, Paula Simplicio da Silva, Gilberto Marcelo Sperandio da Silva, Roberta Olmo Pinheiro, Andréa Silvestre de Sousa, Mauro Felippe Felix Mediano   +7 more
doaj   +1 more source

Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects. [PDF]

PLoS ONE, 2013
BACKGROUND:Familial aggregation of Chagas cardiac disease in T. cruzi-infected persons suggests that human genetic variation may be an important determinant of disease progression.
Xutao Deng, Ester C Sabino, Edecio Cunha-Neto, Antonio L Ribeiro, Barbara Ianni, Charles Mady, Michael P Busch, Mark Seielstad, REDSII Chagas Study Group from the NHLBI Retrovirus Epidemiology Donor Study-II Component International   +8 more
doaj   +1 more source

IL‐33/ST2 Signaling Sustains Hepato‐Intestinal Homeostasis by Orchestrating Vascular Surveillance and Immune Regulatory Circuits During Experimental Trypanosoma cruzi Infection

The FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Impairment of hepato‐intestinal homeostasis triggered by ST2 deficiency during T. cruzi infection. Within the splenic compartment, immune dysregulation is marked by a robust pro‐inflammatory polarization of the T‐cell landscape. In the liver, ST2 deficiency is associated with hepatocellular injury, increased parasite burden, and hyperalbuminemia ...
Marcelo Eduardo Cardozo, Tatyane Martins Cirilo, José Bryan da Rocha Rihs, Jorge Lucas Nascimento Souza, Isabela de Brito Duval, Ana Rafaela Antunes‐Porto, Luisa Vitor Braga do Amaral, Fernando Bento Rodrigues Oliveira, Mayra Fernanda Ricci, Laura Lis de Oliveira Santos, Lívia Fernanda Dias Santana, Luiza Pinheiro Silva, Chiara Cássia Oliveira Amorim, Gabriela Gomes Monteiro Lemos, Getulío Mota e Silva Junior, Izabela da Silva Oliveira, Marina Possa dos Reys, Ana Laura Grossi de Oliveira, Geovanni Dantas Cassali, Luisa Mourão Dias Magalhães, Lilian Lacerda Bueno, Fabiana Simão Machado, Ricardo Toshio Fujiwara   +22 more
wiley   +1 more source

Association of caspase-1 polymorphisms with Chagas cardiomyopathy among individuals in Santa Cruz, Bolivia

Revista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION: Trypanosoma cruzi (Tc) infection is usually acquired in childhood in endemic areas, leading to Chagas disease, which progresses to Chagas cardiomyopathy in 20-30% of infected individuals over decades.
Katherine Yih-Jia Fu, Roxana Zamudio, Jo Henderson-Frost, Alex Almuedo, Hannah Steinberg, Steven Joseph Clipman, Gustavo Duran, Rachel Marcus, Thomas Crawford, Daniel Alyesh, Rony Colanzi, Jorge Flores, Robert Hugh Gilman, Caryn Bern   +13 more
doaj   +1 more source