Results 31 to 40 of about 12,135 (209)

Longitudinal study of patients with chronic Chagas cardiomyopathy in Brazil (SaMi-Trop project): a cohort profile. [PDF]

, 2016
PurposeWe have established a prospective cohort of 1959 patients with chronic Chagas cardiomyopathy to evaluate if a clinical prediction rule based on ECG, brain natriuretic peptide (BNP) levels, and other biomarkers can be useful in clinical practice ...
Bierrenbach, Ana Luiza, Cardoso, Clareci Silva, Cunha-Neto, Edécio, de Oliveira, Lea Campos, Ferreira, Ariela Mota, Ferreira, João Eduardo, Haikal, Desirée Sant'Ana, Oliveira, Claudia Di Lorenzo, Reingold, Arthur L, Ribeiro, Antonio Luiz P, Sabino, Ester Cerdeira   +10 more
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Contemporary characteristics and outcomes in chagasic heart failure compared with other nonischemic and ischemic cardiomyopathy [PDF]

, 2017
Background: Chagas’ disease is an important cause of cardiomyopathy in Latin America. We aimed to compare clinical characteristics and outcomes in patients with heart failure (HF) with reduced ejection fraction caused by Chagas’ disease, with other ...
Claudio R. Gimpelewicz, Efraín A. Gómez, Felipe Martinez, Felix Ramires, Jean L. Rouleau, John J.V. McMurray, Karl Swedberg, Kenneth Dickstein, Lars Køber, Li Shen, Luis Eduardo Echeverría, Luiz Carlos Bodanese, Michael R. Zile, Milton Packer, null null, Pardeep S. Jhund, Scott D. Solomon, William T. Abraham   +17 more
core   +3 more sources

Treatment with a New Peroxisome Proliferator-Activated Receptor Gamma Agonist, Pyridinecarboxylic Acid Derivative, Increases Angiogenesis and Reduces Inflammatory Mediators in the Heart of Trypanosoma cruzi-Infected Mice [PDF]

, 2017
Trypanosoma cruzi infection induces an intense inflammatory response in diverse host tissues. The immune response and the microvascular abnormalities associated with infection are crucial aspects in the generation of heart damage in Chagas disease.
Carta, Davide, Cevey, Ágata Carolina, Dmytrenko, Ganna, Ferlin, Maria Grazia, Goren, Nora Beatriz, Mirkin, Gerardo Ariel Isidoro, Modenutti, Carlos Pablo, Penas, Federico Nicolás, Rada, Maria Jimena, Sales, María Elena   +9 more
core   +4 more sources

Increased plasma levels of tumor necrosis factor-alpha in asymptomatic/"indeterminate" and Chagas disease cardiomyopathy patients [PDF]

Memorias do Instituto Oswaldo Cruz, 2003
We compared plasma tumor necrosis factor-alpha (TNF-alpha) levels among asymptomatic/"indeterminate" Chagas disease patients (ASY) and patients across the clinical spectrum of chronic Chagas disease cardiomyopathy (CCC). Idiopathic dilated cardiomyopathy
Renata Cristina Ferreira, Barbara M Ianni, Lucia CJ Abel, Paula Buck, Charles Mady, Jorge Kalil, Edecio Cunha-Neto   +6 more
doaj   +1 more source

Gap junction reduction in cardiomyocytes following transforming growth factor- beta treatment and Trypanosoma cruzi infection [PDF]

, 2009
Gap junction connexin-43 (Cx43) molecules are responsible for electrical impulse conduction in the heart and are affected by transforming growth factor-beta (TGF-beta).
Becker, D, Burnstock, G, Coutinho-Silva, R, de Araujo-Jorge, TC, Feige, JJ, Higuchi, MD, Waghabi, MC   +6 more
core   +2 more sources

Chagas cardiomyopathy: Europe is not spared! [PDF]

European Heart Journal, 2008
Chagas’ disease was first described in 1909 by the Brazilian physician Carlos Chagas, who named the parasite Trypanosoma cruzi after his mentor, Oswaldo Cruz.1 It causes more deaths in the Americas than any other parasitic disease.1 Due to the parasite distribution throughout Central and South America, it is commonly known as the ‘American ...
Guerri Guttemberg R, Grana DR, AMBROSIO, Giuseppe, Milei J.   +3 more
openaire   +2 more sources

Chagas disease reactivation in a heart transplant patient infected by domestic Trypanosoma cruzi discrete typing unit I (TcIDOM) [PDF]

, 2015
Background Trypanosoma cruzi, causative agent of Chagas disease, displays high intraspecific genetic diversity: six genetic lineages or discrete typing units (DTUs) are currently recognized, termed TcI through TcVI.
Bhattacharyya, T., Burleigh, B.A., Costales, J.A., Garcia-Perez, J., Kotton, C.N., Llewellyn, M.S., Messenger, L.A., Zurita-Leal, A.C.   +7 more
core   +2 more sources

Evaluation of the six-minute walk test in patients with chronic heart failure associated with Chagas' disease and systemic arterial hypertension Avaliação do teste de caminhada de seis minutos em pacientes com insuficiência cardíaca crônica associada à doença de Chagas e hipertensão arterial sistêmica

Revista da Sociedade Brasileira de Medicina Tropical, 2010
INTRODUCTION: To evaluate physical capacity as determined by the six-minute walk test (6MWT) in patients with chronic heart failure due to Chagas' disease associated with systemic arterial hypertension (Chagas-SAH).
Kelly Cristina Colaço Dourado, Reinaldo Bulgarelli Bestetti, Augusto Cardinalli-Neto, José Antônio Cordeiro   +3 more
doaj   +1 more source

Scientometrics analysis of research activity and collaboration patterns in Chagas cardiomyopathy. [PDF]

PLoS Neglected Tropical Diseases, 2018
Chagas cardiomyopathy is a serious and common complication of Chagas disease.Through bibliometric and Social Network Analysis, we examined patterns of research on Chagas cardiomyopathy, identifying the main countries, authors, research clusters, and ...
Gregorio González-Alcaide, Alejandro Salinas, José M Ramos   +2 more
doaj   +1 more source

Developments in the management of Chagas cardiomyopathy [PDF]

Expert Review of Cardiovascular Therapy, 2015
Over 100 years have elapsed since the discovery of Chagas disease and there is still much to learn regarding pathogenesis and treatment. Although there are antiparasitic drugs available, such as benznidazole and nifurtimox, they are not totally reliable and often toxic.
Herbert B, Tanowitz, Fabiana S, Machado, David C, Spray, Joel M, Friedman, Oren S, Weiss, Jose N, Lora, Jyothi, Nagajyothi, Diego N, Moraes, Nisha Jain, Garg, Maria Carmo P, Nunes, Antonio Luiz P, Ribeiro   +10 more
openaire   +2 more sources