Results 21 to 30 of about 178,801 (195)

Chagas Disease Cardiomyopathy: Immunopathology and Genetics [PDF]

Mediators of Inflammation, 2014
Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America and affects ca. 10 million people worldwide. About 30% of Chagas disease patients develop chronic Chagas disease cardiomyopathy (CCC), a particularly lethal ...
Edecio Cunha-Neto, Christophe Chevillard
doaj   +3 more sources

Chagas Disease Cardiomyopathy

International Journal of Cardiovascular Sciences, 2018
Abstract Chronic Chagas disease cardiomyopathy (CCC) is a result of low-intensity, but incessant, focal fibrosing myocarditis, caused by persistent T. cruzi infection associated with inflammation, mediated by adverse immune mechanisms. About 30 percent of infected individuals have developed throughout life the chronic cardiac form of Chagas' disease ...
Simões, Marcus Vinicius, Romano, Minna Moreira Dias, Schmidt, André, Martins, Káryta Suely Macedo, Marin-Neto, José Antonio   +4 more
openaire   +4 more sources

Angiotensin Receptor-Neprilysin Inhibition in Chagas Cardiomyopathy: Clinical Practice Update [PDF]

Journal of Education, Health and Sport
Background: Chronic Chagas cardiomyopathy is an arrhythmogenic, fibrosis-prone form of heart failure that develops years after Trypanosoma cruzi infection. Standard therapy has largely been extrapolated from non-Chagas trials.
Katarzyna Skibicka, Weronika Wesołowska, Tomasz Skibicki, Robert Bujak   +3 more
doaj   +2 more sources

Electro-Mechanical Dissociation in Chagas Cardiomyopathy: Comparative Analysis of Arrhythmic Burden Beyond LVEF. [PDF]

J Arrhythm
Despite matched clinical characteristics and LVEF, patients with Chagas cardiomyopathy exhibit a significantly higher arrhythmic burden compared to ischemic cardiomyopathy. This electro‐mechanical dissociation highlights the necessity of sudden death risk stratification strategies that extend beyond traditional ejection fraction thresholds.
Echeverría LE, Rojas LZ, Serrano-García AY, Ariza YT, Luengas C, Marcus R, Morillo CA, Gómez-Ochoa SA.   +7 more
europepmc   +2 more sources

Biomakers in Chronic Chagas Cardiomyopathy

Microorganisms, 2022
The primary objective was to observe the relationship between serum levels of BNP, Ca-125, C-reactive protein and uric acid as prognostic and functional markers in patients with chronic Chagas cardiomyopathy (CCC). Circulating levels of cytokines: IL-1β, TNFα, IL-10, IL6, IL-8 and IL-12 were determined and investigated regarding their association with ...
Rodrigues, Angela Braga, Torres, Henrique Oswaldo da Gama, Nunes, Maria do Carmo Pereira, Gomes, Juliana de Assis Silva, Rodrigues, Aline Braga, Pinho, Laura Lopes Nogueira, Rocha, Manoel Otavio, Botoni, Fernando Antonio   +7 more
openaire   +3 more sources

Baseline characteristics the evaluated chronic Chagas cardiomyopathy patients (n = 100).

, 2021
Baseline characteristics the evaluated chronic Chagas cardiomyopathy patients (n = 100).
Cristian David Sosa-Vesga (11619210), Luis E. Echeverría (5390993), Taulant Muka (754244), Sergio Alejandro Gómez-Ochoa (6300878), James L. Januzzi (11619213), Carlos A. Morillo (8438394), Oscar L. Rueda-Ochoa (5390987), Rachel Marcus (11619216), Lyda Z. Rojas (5390996)   +8 more
core   +1 more source

Chagas cardiomyopathy: Europe is not spared! [PDF]

European Heart Journal, 2008
Chagas’ disease was first described in 1909 by the Brazilian physician Carlos Chagas, who named the parasite Trypanosoma cruzi after his mentor, Oswaldo Cruz.1 It causes more deaths in the Americas than any other parasitic disease.1 Due to the parasite distribution throughout Central and South America, it is commonly known as the ‘American ...
Guerri Guttemberg R, Grana DR, AMBROSIO, Giuseppe, Milei J.   +3 more
openaire   +2 more sources

Different infective forms trigger distinct immune response in experimental Chagas disease. [PDF]

, 2012
Although metacyclic and blood trypomastigotes are completely functional in relation to parasite-host interaction and/or target cell invasion, they differ in the molecules present on the surface.
Olindo Assis Martins-Filho, Carneiro Cláudia Martins, Martins-Filho, Olindo Assis, Alexandre Barbosa Reis, Cláudia Martins Carneiro, Francisco Amanda Fortes, Washington Luiz Tafuri, Carvalho, Andrea Teixeira, Machado Evandro Marques de Meneses, Nogueira, Nívia Carolina, Franscisco, Amanda Fortes, Evandro Marques de Meneses Machado, Vieira, Paula Melo de Abreu, Fonseca, Kátia da Silva, Francisco, Amanda Fortes, Andrea Teixeira-Carvalho, Paula Melo de Abreu Vieira, Nogueira, N??via Carolina, Machado, Evandro Marques de Menezes, Vieira Paula Melo de Abreu, Machado, Evandro Marques de Meneses, Tafuri, Washington Luiz, Reis Alexandre Barbosa, Teixeira-Carvalho Andrea, Reis, Alexandre Barbosa, Martins-Filho Olindo Assis, Nívia Carolina Nogueira, Kátia da Silva Fonseca, Carvalho, Andréa Teixeira de, Nogueira Nívia Carolina, Amanda Fortes Francisco, Tafuri Washington Luiz, Teixeira-Carvalho, Andrea, Carneiro, Cláudia Martins, Martins Filho, Olindo Assis, Fonseca Kátia da Silva   +35 more
core   +2 more sources

Increased plasma levels of tumor necrosis factor-alpha in asymptomatic/"indeterminate" and Chagas disease cardiomyopathy patients [PDF]

Memorias do Instituto Oswaldo Cruz, 2003
We compared plasma tumor necrosis factor-alpha (TNF-alpha) levels among asymptomatic/"indeterminate" Chagas disease patients (ASY) and patients across the clinical spectrum of chronic Chagas disease cardiomyopathy (CCC). Idiopathic dilated cardiomyopathy
Renata Cristina Ferreira, Barbara M Ianni, Lucia CJ Abel, Paula Buck, Charles Mady, Jorge Kalil, Edecio Cunha-Neto   +6 more
doaj   +1 more source

Evaluation of the six-minute walk test in patients with chronic heart failure associated with Chagas' disease and systemic arterial hypertension Avaliação do teste de caminhada de seis minutos em pacientes com insuficiência cardíaca crônica associada à doença de Chagas e hipertensão arterial sistêmica

Revista da Sociedade Brasileira de Medicina Tropical, 2010
INTRODUCTION: To evaluate physical capacity as determined by the six-minute walk test (6MWT) in patients with chronic heart failure due to Chagas' disease associated with systemic arterial hypertension (Chagas-SAH).
Kelly Cristina Colaço Dourado, Reinaldo Bulgarelli Bestetti, Augusto Cardinalli-Neto, José Antônio Cordeiro   +3 more
doaj   +1 more source