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Clinical Presentations of Chagas Cardiomyopathy
Chronic Chagas cardiomyopathy (CCC) is the most common cause of nonischemic cardiomyopathy in endemic Latin American countries. Immigrants to the United States suffer from this disease, but it is underrecognized.
Malik Shehadeh, Ana Barac, Rachel Marcus
doaj +4 more sources
Treatment of Chagas Cardiomyopathy [PDF]
Chagas' disease (ChD), caused by the protozoaTrypanosoma cruzi(T. cruzi), was discovered and described by the Brazilian physician Carlos Chagas in 1909. After a century of original description, trypanosomiasis still brings much misery to humanity and is classified as a neglected tropical disease prevalent in underdeveloped countries, particularly in ...
Botoni, Fernando A. +5 more
core +6 more sources
Abstract Chagas disease is a prominent neglected tropical disease endemic to many countries in Latin America. Cardiomyopathy is the most serious manifestation due to the severity and complications of heart failure. As a result of expanded immigration and globalization, there is an increased number of patients with Chagas cardiomyopathy who are being ...
Ariana, Jimenez, Elizabeth J, Winokur
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GWAS loci associated with Chagas cardiomyopathy influences DNA methylation levels [PDF]
A recent genome-wide association study (GWAS) identified a locus in chromosome 11 associated with the chronic cardiac form of Chagas disease. Here we aimed to elucidate the potential functional mechanism underlying this genetic association by analyzing ...
Desiré Casares-Marfil +7 more
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Rapidly Progressing Chagas Cardiomyopathy [PDF]
Chagas disease, caused by the parasite Trypanosoma cruzi, can cause a potentially life-threatening cardiomyopathy in approximately 10–40% of afflicted individuals. The decline in cardiac function characteristically progresses over the course of many years.
Hollowed, John +5 more
openaire +7 more sources
Heart transplantation for Chagas cardiomyopathy
Chagas disease is an endemic disease in Latin America that is increasingly found in non-endemic areas all over the world due to the flow of migrants from Central and South America.
Ana Rita Ramalho +4 more
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Chagas cardiomyopathy, caused by the protozoal parasite Trypanosoma cruzi, is characterized by arrhythmias, myocardial damage, heart failure, and sudden death.
Elizabeth L. Malcolm +4 more
doaj +2 more sources
Introduction: Chagas disease is an under-recognized cause of cardiomyopathy in the United States, and cardiac involvement may present decades after exposure with heart failure or ventricular arrhythmias.
Aida A. Metri, MD +7 more
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First described by Carlos Justiniano Ribeiro Chagas (1879-1934) in 1909, Chagas disease (CD) or American trypanosomiasis is caused by the protozoan parasite Trypanosoma cruzi.
Vera Demarchi Aiello +1 more
doaj +4 more sources
Pathogenesis of chronic Chagas cardiomyopathy: the role of coronary microvascular derangements [PDF]
There is ample experimental and clinical evidence of functional and structural microvascular abnormalities occurring in patients with Chagas cardiomyopathy, possibly due to the inflammatory process and/or autonomic disturbances caused by Trypanosoma ...
Jose Antonio Marin-Neto +2 more
doaj +2 more sources

