Circulating microRNAs as biomarkers of Chagas cardiomyopathy [PDF]
BackgroundChagas cardiomyopathy (CHCM) is the most important clinical manifestation of Chagas disease. The analysis of cardiac miRNAs may contribute to predicting the progression to CHCM in Chagas indeterminate phase and/or to the differential diagnosis ...
Laura Antonietti +13 more
doaj +5 more sources
Heart transplantation for Chagas cardiomyopathy
Chagas disease is an endemic disease in Latin America that is increasingly found in non-endemic areas all over the world due to the flow of migrants from Central and South America.
Ana Rita Ramalho +4 more
doaj +6 more sources
Mortality Risk in Chronic Chagas Cardiomyopathy: A Systematic Review and Meta-Analysis
Aims This study aimed to estimate the annual mortality risk and its determinants in chronic Chagas cardiomyopathy. Methods and results We conducted a systematic search in MEDLINE, Web of Science Core Collection, Embase, Cochrane Library, and LILACS ...
Sindhu Chadalawada +2 more
exaly +2 more sources
Electrocardiographic Abnormalities and Treatment with Benznidazole among Children with Chronic Infection by Trypanosoma cruzi: A Retrospective Cohort Study [PDF]
Background: Chronic infection by Trypanosoma cruzi could cause heart conduction disturbances. We sought to analyze electrocardiographic abnormalities among children with chronic T. cruzi infection with and without trypanocidal treatment with benznidazole.
Colantonio, Lisandro Damián +3 more
core +31 more sources
First described by Carlos Justiniano Ribeiro Chagas (1879-1934) in 1909, Chagas disease (CD) or American trypanosomiasis is caused by the protozoan parasite Trypanosoma cruzi.
Vera Demarchi Aiello +1 more
doaj +4 more sources
Clinical Presentations of Chagas Cardiomyopathy
Chronic Chagas cardiomyopathy (CCC) is the most common cause of nonischemic cardiomyopathy in endemic Latin American countries. Immigrants to the United States suffer from this disease, but it is underrecognized.
Malik Shehadeh, Ana Barac, Rachel Marcus
doaj +3 more sources
Echocardiographic predictors of mortality in heart failure from Chagas cardiomyopathy: Refining risk stratification with speckle-tracking echocardiography [PDF]
Background: Chagas cardiomyopathy is a major cause of mortality in endemic regions, predicted primarily by left ventricular (LV) systolic function. Speckle-tracking echocardiography (STE)–derived strain is a sensitive tool for assessing ventricular ...
Marcelo Alves Maia +10 more
doaj +2 more sources
Chagas Disease Cardiomyopathy: Immunopathology and Genetics [PDF]
Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America and affects ca. 10 million people worldwide. About 30% of Chagas disease patients develop chronic Chagas disease cardiomyopathy (CCC), a particularly lethal ...
Edecio Cunha-Neto, Christophe Chevillard
doaj +3 more sources
Stroke in Chagas disease: from pathophysiology to clinical practice [PDF]
Despite substantial progress toward its control, Chagas disease continues to be a major public health problem in Latin America and has become a global health concern.
Thaís Aparecida Reis Lage +6 more
doaj +1 more source
Treatment of Chagas Cardiomyopathy [PDF]
Chagas' disease (ChD), caused by the protozoaTrypanosoma cruzi(T. cruzi), was discovered and described by the Brazilian physician Carlos Chagas in 1909. After a century of original description, trypanosomiasis still brings much misery to humanity and is classified as a neglected tropical disease prevalent in underdeveloped countries, particularly in ...
Botoni, Fernando A. +5 more
openaire +3 more sources

