Results 11 to 20 of about 5,576 (168)
Heart transplantation for Chagas cardiomyopathy
Revista Portuguesa de Cardiologia, 2017 Chagas disease is an endemic disease in Latin America that is increasingly found in non-endemic areas all over the world due to the flow of migrants from Central and South America.
Ana Rita Ramalho +4 more
doaj +6 more sources
Autopsy and Case Reports, 2015 First described by Carlos Justiniano Ribeiro Chagas (1879-1934) in 1909, Chagas disease (CD) or American trypanosomiasis is caused by the protozoan parasite Trypanosoma cruzi.
Vera Demarchi Aiello +1 more
doaj +4 more sources
Clinical Presentations of Chagas Cardiomyopathy
Case Reports in Cardiology, 2020 Chronic Chagas cardiomyopathy (CCC) is the most common cause of nonischemic cardiomyopathy in endemic Latin American countries. Immigrants to the United States suffer from this disease, but it is underrecognized.
Malik Shehadeh, Ana Barac, Rachel Marcus
doaj +3 more sources
Chagas Disease Cardiomyopathy: Immunopathology and Genetics [PDF]
Mediators of Inflammation, 2014 Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America and affects ca. 10 million people worldwide. About 30% of Chagas disease patients develop chronic Chagas disease cardiomyopathy (CCC), a particularly lethal ...
Edecio Cunha-Neto, Christophe Chevillard
doaj +3 more sources
Treatment of Chagas Cardiomyopathy [PDF]
BioMed Research International, 2013 Chagas' disease (ChD), caused by the protozoaTrypanosoma cruzi(T. cruzi), was discovered and described by the Brazilian physician Carlos Chagas in 1909. After a century of original description, trypanosomiasis still brings much misery to humanity and is classified as a neglected tropical disease prevalent in underdeveloped countries, particularly in ...
Botoni, Fernando A. +5 more
openaire +3 more sources
Biomakers in Chronic Chagas Cardiomyopathy. [PDF]
Microorganisms, 2022 The primary objective was to observe the relationship between serum levels of BNP, Ca-125, C-reactive protein and uric acid as prognostic and functional markers in patients with chronic Chagas cardiomyopathy (CCC). Circulating levels of cytokines: IL-1β, TNFα, IL-10, IL6, IL-8 and IL-12 were determined and investigated regarding their association with ...
Rodrigues AB +7 more
europepmc +4 more sources
Rapidly Progressing Chagas Cardiomyopathy [PDF]
The American Society of Tropical Medicine and Hygiene, 2016 Chagas disease, caused by the parasite Trypanosoma cruzi, can cause a potentially life-threatening cardiomyopathy in approximately 10–40% of afflicted individuals. The decline in cardiac function characteristically progresses over the course of many years.
Hollowed, John +5 more
openaire +5 more sources
GWAS loci associated with Chagas cardiomyopathy influences DNA methylation levels
PLoS Neglected Tropical Diseases, 2021 A recent genome-wide association study (GWAS) identified a locus in chromosome 11 associated with the chronic cardiac form of Chagas disease. Here we aimed to elucidate the potential functional mechanism underlying this genetic association by analyzing ...
Desiré Casares-Marfil +7 more
doaj +2 more sources
Mitochondrial DNA Haplogroups and Variants Predispose to Chagas Disease Cardiomyopathy
Hearts, 2023 Cardiomyopathies are major causes of heart failure. Chagas disease (CD) is caused by the parasite Trypanosoma cruzi, and it is endemic in Central and South America.
Frédéric Gallardo +39 more
doaj +1 more source
Increased plasma levels of tumor necrosis factor-alpha in asymptomatic/"indeterminate" and Chagas disease cardiomyopathy patients [PDF]
Memorias do Instituto Oswaldo Cruz, 2003 We compared plasma tumor necrosis factor-alpha (TNF-alpha) levels among asymptomatic/"indeterminate" Chagas disease patients (ASY) and patients across the clinical spectrum of chronic Chagas disease cardiomyopathy (CCC). Idiopathic dilated cardiomyopathy
Renata Cristina Ferreira +6 more
doaj +1 more source