Results 11 to 20 of about 707 (123)

Treatment of Chagas Cardiomyopathy [PDF]

BioMed Research International, 2013
Chagas' disease (ChD), caused by the protozoaTrypanosoma cruzi(T. cruzi), was discovered and described by the Brazilian physician Carlos Chagas in 1909. After a century of original description, trypanosomiasis still brings much misery to humanity and is classified as a neglected tropical disease prevalent in underdeveloped countries, particularly in ...
Botoni, Fernando A., Ribeiro, Antonio Luiz P., Marinho, Carolina Coimbra, Lima, Marcia Maria Oliveira, Nunes, Maria do Carmo Pereira, Rocha, Manoel Otávio C.   +5 more
openaire   +3 more sources

Sustained monomorphic ventricular tachycardia as the presenting sign of Chagas’ cardiomyopathy in a low prevalence setting, diagnosis and management challenges. A case report

Therapeutic Advances in Infectious Disease, 2022
Approximately 300,000 people in the United States are estimated to have Chagas’ disease, with cardiac manifestations including arrhythmias occurring in 20%–30% of patients.
Devang R. Amin, Sean Behan, Michelle Pengshung, Amber Khanna, Wendy S. Tzou, Nicholas Mantini, Andrés F. Henao-Martinez, Alexis Tumolo, Daniel W. Groves   +8 more
doaj   +1 more source

Deficient regulatory T cell activity and low frequency of IL-17-producing T cells correlate with the extent of cardiomyopathy in human Chagas' disease. [PDF]

PLoS Neglected Tropical Diseases, 2012
BACKGROUND: Myocardium damage during Chagas' disease results from the immunological imbalance between pro- and production of anti-inflammatory cytokines and has been explained based on the Th1-Th2 dichotomy and regulatory T cell activity.
Paulo Marcos Matta Guedes, Fredy Roberto Salazar Gutierrez, Grace Kelly Silva, Renata Dellalibera-Joviliano, Gerson Jhonatan Rodrigues, Lusiane Maria Bendhack, Anis Rassi, Anis Rassi, André Schmidt, Benedito Carlos Maciel, José Antonio Marin Neto, João Santana Silva   +11 more
doaj   +1 more source

Stroke correlates in chagasic and non-chagasic cardiomyopathies. [PDF]

PLoS ONE, 2012
BACKGROUND: Aging and migration have brought changes to the epidemiology and stroke has been shown to be independently associated with Chagas disease.
José Alberto Martins da Matta, Roque Aras, Cristiano Ricardo Bastos de Macedo, Cristiano Gonçalves da Cruz, Eduardo Martins Netto   +4 more
doaj   +1 more source

Association of left ventricular abnormalities with incident cerebrovascular events and sources of thromboembolism in patients with chronic Chagas cardiomyopathy

Journal of Cardiovascular Magnetic Resonance, 2022
Background Although Chagas cardiomyopathy is related to thromboembolic stroke, data on risk factors for cerebrovascular events in Chagas disease is limited.
Henrique Turin Moreira, Gustavo Jardim Volpe, Gustavo Marques Mesquita, Maria Fernanda Braggion-Santos, Antonio Pazin-Filho, José Antonio Marin-Neto, André Schmidt   +6 more
doaj   +1 more source

Antiparasitic treatment with itraconazole and amiodarone in 2 dogs with severe, symptomatic Chagas cardiomyopathy

Journal of Veterinary Internal Medicine, 2022
Chagas cardiomyopathy, caused by the protozoal parasite Trypanosoma cruzi, is characterized by arrhythmias, myocardial damage, heart failure, and sudden death.
Elizabeth L. Malcolm, Ashley B. Saunders, Jordan P. Vitt, Bruno G. Boutet, Sarah A. Hamer   +4 more
doaj   +1 more source

Mitochondrial DNA Haplogroups and Variants Predispose to Chagas Disease Cardiomyopathy

Hearts, 2023
Cardiomyopathies are major causes of heart failure. Chagas disease (CD) is caused by the parasite Trypanosoma cruzi, and it is endemic in Central and South America.
Frédéric Gallardo, Pauline Brochet, David Goudenège, João Paulo Silva Nunes, Pauline Andrieux, Barbara Maria Ianni, Amanda Farage Frade, Charles Mady, Ronaldo Honorato Barros Santos, Andreia Kuramoto, Samuel Steffen, Antonio Noedir Stolf, Pablo Pomerantzeff, Alfredo Inacio Fiorelli, Edimar Alcides Bocchi, Cristina Wide Pissetti, Bruno Saba, Fabrício C. Dias, Marcelo Ferraz Sampaio, Fabio Antônio Gaiotto, José Antonio Marin-Neto, Abílio Fragata, Ricardo Costa Fernandes Zaniratto, Sergio Siqueira, Giselle De Lima Peixoto, Fernando Bacal, Paula Buck, Rafael Ribeiro Almeida, Hui Tzu Lin-Wang, André Schmidt, Mario Hiroyuki Hirata, Eduardo Antonio Donadi, Alexandre Costa Pereira, Virmondes Rodrigues Junior, Martino Martinelli, Michel Naslavsky, Jorge Kalil, Vincent Procaccio, Edecio Cunha-Neto, Christophe Chevillard   +39 more
doaj   +1 more source

GWAS loci associated with Chagas cardiomyopathy influences DNA methylation levels

PLoS Neglected Tropical Diseases, 2021
A recent genome-wide association study (GWAS) identified a locus in chromosome 11 associated with the chronic cardiac form of Chagas disease. Here we aimed to elucidate the potential functional mechanism underlying this genetic association by analyzing ...
Desiré Casares-Marfil, Martin Kerick, Eduardo Andrés-León, Pau Bosch-Nicolau, Israel Molina, Chagas Genetics CYTED Network, Javier Martin, Marialbert Acosta-Herrera   +7 more
doaj   +2 more sources

Rapidly Progressing Chagas Cardiomyopathy [PDF]

The American Society of Tropical Medicine and Hygiene, 2016
Chagas disease, caused by the parasite Trypanosoma cruzi, can cause a potentially life-threatening cardiomyopathy in approximately 10–40% of afflicted individuals. The decline in cardiac function characteristically progresses over the course of many years.
Hollowed, John, McCullough, Matthew, Sanchez, Daniel, Traina, Mahmoud, Hernandez, Salvador, Murillo, Efrain   +5 more
openaire   +5 more sources

Chagas cardiomyopathy: Europe is not spared! [PDF]

European Heart Journal, 2008
Chagas’ disease was first described in 1909 by the Brazilian physician Carlos Chagas, who named the parasite Trypanosoma cruzi after his mentor, Oswaldo Cruz.1 It causes more deaths in the Americas than any other parasitic disease.1 Due to the parasite distribution throughout Central and South America, it is commonly known as the ‘American ...
Guerri Guttemberg R, Grana DR, AMBROSIO, Giuseppe, Milei J.   +3 more
openaire   +2 more sources