Results 51 to 60 of about 12,135 (209)

The Ly49E receptor inhibits the immune control of acute Trypanosoma cruzi infection [PDF]

open access: yes, 2016
The protozoan parasite Trypanosoma cruzi circulates in the blood upon infection and invades various cells. Parasites intensively multiply during the acute phase of infection and persist lifelong at low levels in tissues and blood during the chronic phase.
Almeida   +48 more
core   +2 more sources

TcI isolates of Trypanosoma cruzi exploit the antioxidant network for enhanced intracellular survival in macrophages and virulence in mice [PDF]

open access: yes, 2016
Trypanosoma cruzi species is categorized into six discrete typing units (TcI to TcVI) of which TcI is most abundantly noted in the sylvatic transmission cycle and considered the major cause of human disease. In our study, the TcI strains Colombiana (COL),
Basombrío, Miguel Ángel Manuel   +8 more
core   +3 more sources

Management of trypanosomiasis and leishmaniasis [PDF]

open access: yes, 2012
<p>Background: The current treatments for human African trypanosomiasis (HAT), Chagas disease and leishmaniasis (collectively referred to as the kinetoplastid diseases) are far from ideal but, for some, there has been significant recent progress ...
Alsford   +39 more
core   +2 more sources

Elevated serum levels of macrophage migration inhibitory factor and stem cell growth factor β in patients with idiopathic and systemic sclerosis associated pulmonary arterial hypertension. [PDF]

open access: yes, 2015
Pulmonary arterial hypertension (PAH) can be idiopathic or secondary to autoimmune diseases, and it represents one of the most threatening complications of systemic sclerosis (SSc).
Alessandri, Cristiano   +9 more
core   +2 more sources

Paracoccidioidomycosis in Brazil: 25‐Year Nationwide Trends in Mortality, Hospitalisations and In‐Hospital Deaths of a Neglected Systemic Mycosis

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Objective To analyse mortality, hospitalisations and in‐hospital mortality related to paracoccidioidomycosis (PCM) in Brazil, 2000–2024, from a spatio‐temporal and social inequalities perspective. Methods We conducted a mixed ecological study using death certificates from the Mortality Information System and hospital admissions from the ...
Anderson Fuentes Ferreira   +9 more
wiley   +1 more source

Biomarkers and Mortality in Severe Chagas Cardiomyopathy [PDF]

open access: yesGlobal Heart, 2015
Chagas cardiomyopathy is a chronic sequela of infection by the parasite, Trypanosoma cruzi. Advanced cardiomyopathy is associated with a high mortality rate, and clinical characteristics have been used to predict mortality risk. Though multiple biomarkers have been associated with Chagas cardiomyopathy, it is unknown how these are related to survival ...
Sherbuk, Jacqueline E.   +13 more
openaire   +3 more sources

Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND:Familial aggregation of Chagas cardiac disease in T. cruzi-infected persons suggests that human genetic variation may be an important determinant of disease progression.
Xutao Deng   +8 more
doaj   +1 more source

Canine Trypanosoma cruzi infection in the Bolivian Chaco [PDF]

open access: yes, 2018
A cross-sectional study on Trypanosoma cruzi was carried out in 2013 to evaluate the role of dogs as possible source of infection for humans in two rural communities of the highly endemic Bolivian Chaco (Bartolo, Chuquisaca Department, n = 57 dogs; and ...
Bartoloni, Alessandro   +9 more
core   +2 more sources

Electro‐Mechanical Dissociation in Chagas Cardiomyopathy: Comparative Analysis of Arrhythmic Burden Beyond LVEF

open access: yesJournal of Arrhythmia, Volume 42, Issue 3, June 2026.
Despite matched clinical characteristics and LVEF, patients with Chagas cardiomyopathy exhibit a significantly higher arrhythmic burden compared to ischemic cardiomyopathy. This electro‐mechanical dissociation highlights the necessity of sudden death risk stratification strategies that extend beyond traditional ejection fraction thresholds.
Luis E. Echeverría   +7 more
wiley   +1 more source

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