Results 71 to 80 of about 12,135 (209)

Pathogenesis of chronic Chagas cardiomyopathy: the role of coronary microvascular derangements

Revista da Sociedade Brasileira de Medicina Tropical, 2013
There is ample experimental and clinical evidence of functional and structural microvascular abnormalities occurring in patients with Chagas cardiomyopathy, possibly due to the inflammatory process and/or autonomic disturbances caused by Trypanosoma ...
Jose Antonio Marin-Neto, Marcus Vinicius Simoes, Anis Rassi Junior   +2 more
doaj   +1 more source

Review of Chagas Disease and Treatment Obstacles to Eradication [PDF]

, 2019
The World Health Organization and the Center for Disease Control reports Chagas disease, or American trypanosomiasis, as a major neglected tropical disease prevalent in 21 endemic Latin American countries.
Sherman, Emily
core   +1 more source

A Case of Heart Failure With Reduced Ejection Fraction Secondary to Dilated Cardiomyopathy due to Long‐Standing Untreated Acromegaly: A Case Report and Focused Literature Review

Clinical Case Reports, Volume 14, Issue 4, April 2026.
Echocardiographic findings in dilated cardiomyopathy secondary to untreated acromegaly. (A) Apical four‐chamber view showing biventricular and biatrial dilation. (B‐C) Colour Doppler demonstrating mitral, aortic, and tricuspid regurgitation. (D) Reduced global longitudinal strain (GLS: −6.5%), consistent with severe systolic dysfunction.
Cristian Orlando Porras Bueno, Nancy Muriel Herrera Leaño, María Juliana Soto Chávez, Darío Parra Prieto, Alejandro Mariño Correa   +4 more
wiley   +1 more source

Opportunities and Challenges in Chronic Chagas Cardiomyopathy [PDF]

Global Heart, 2015
Chronic Chagas cardiomyopathy (CCC) is the most serious complication of Chagas disease. More than a century after the astute clinician-scientist Carlos Chagas published the etiologic, pathological, clinical, and epidemiological characteristics of the disease that now bears his name [1], much scientific progress has been made.
Mensah, George A., Burns, Kristin M., Peprah, Emmanuel K., Sampson, Uchechukwu K.A., Engelgau, Michael M.   +4 more
openaire   +3 more sources

The burden of congenital Chagas disease and implementation of molecular diagnostic tools in Latin America [PDF]

, 2018
It is estimated that between 8000 and 15 000 Trypanosoma cruzi infected babies are born every year to infected mothers in Chagas disease endemic countries. Currently, poor access to and performance of the current diagnostic algorithm, based on microscopy
Cruz, Israel, Katz, Zachary, Ndung'u, Joseph Mathu, Picado, Albert, Redard Jacot, Maël, Schijman, Alejandro Gabriel, Sosa-Estani, Sergio Alejandro, Torrico, Faustino   +7 more
core   +1 more source

Zhenyuan Solid Drink Ameliorates Inflammation and Oxidative Stress in Isoproterenol‐Induced Ischemic Myocardial Infarction via TLR4/NF‐κB Pathway and PI3K/AKT1/NRF2 Pathway in Rats

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
ZYSD exerts curative and preventive cardioprotection against isoproterenol‐induced myocardial infarction through synergistic interaction with probiotics, exerting antioxidant and anti‐inflammatory effects. ABSTRACT Zhenyuan Solid Drink (ZYSD) is a formulation consisting of 6 medicinal herbs that can be used as both food and medicinal materials in China.
Jiawen Huang, Tian Yu, Guoyi Li, Kechao Nie, Donghua Liu, Cong Meng, Xiaoling Shen, Linchun Fu, Liang Long, Zhuotao Fu, Zhitong Deng, Yingjie Hu   +11 more
wiley   +1 more source

Ex vivo T-lymphocyte chemokine receptor phenotypes in patients with chronic Chagas disease

Revista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION: Elucidating the molecules involved in the inflammatory process of chronic Chagas disease may allow identification of treatment targets.
Matheus Barbosa de Miranda, Adriene Siqueira de Melo, Mariana Silva Almeida, Silvia Martins Marinho, Wilson Oliveira Junior, Yara de Miranda Gomes   +5 more
doaj   +1 more source

Chagas disease cardiomyopathy: current concepts of an old disease Cardiomiopatia chagásica: conceitos atuais de doença antiga

Revista do Instituto de Medicina Tropical de São Paulo, 2008
Chagas disease continues to be a significant public health problem, as ca. 10 million people are still infected with T. cruzi in Latin America. Decades after primary infection, 30% of individuals can develop a form of chronic inflammatory cardiomyopathy ...
Angelina M.B. Bilate, Edecio Cunha-Neto
doaj   +1 more source

Deriving a parsimonious cardiac endpoint for use in epidemiological studies of Chagas disease: results from the Retrovirus Epidemiology Donor Study-II (REDS-II) cohort

Revista do Instituto de Medicina Tropical de São Paulo, 2021
Chagas cardiomyopathy (ChCM) is a severe consequence of Trypanosoma cruzi infection and has a range of electrocardiographic (ECG) and echocardiographic (ECHO) manifestations. There is a need for a standard and parsimonious research cardiac end point that
Lewis F. Buss, Taniela Marli Bes, Alexandre Pereira, Larissa Natany, Claudia Di Lorenzo Oliveira, Antonio Luiz P Ribeiro, Ester Cerdeira Sabino   +6 more
doaj   +1 more source

Rabbit models of heart disease. [PDF]

, 2008
Human heart disease is a major cause of death and disability. A variety of animal models of cardiac disease have been developed to better understand the etiology, cellular and molecular mechanisms of cardiac dysfunction and novel therapeutic strategies ...
Bers, Donald M, Pogwizd, Steven M
core