Results 71 to 80 of about 178,801 (195)

Echocardiographic parameters associated with pulmonary congestion in Chagas cardiomyopathy [PDF]

open access: yes, 2010
INTRODUCTION: Discrepancy between the intensity of pulmonary congestion and the grade of cardiomegaly seems to be a common finding of Chagas cardiomyopathy, in spite of significant systolic dysfunction of the left ventricle.
Cid Sérgio Ferreira   +5 more
core   +1 more source

Current Topics of Progressive Cardiac Conduction Disease

open access: yesJournal of Arrhythmia, Volume 42, Issue 3, June 2026.
Many genes and the protein cause PCCD. Mutation of NaV1.5 or CX40 cause isolated PCCD, but mutation of lamin A/C, emerin, or desmin lead to cardiomyopathy, and PCCD. Mutation of transcription factor NCX2‐5, and Tbx5 associated with atrial septal defect and abnormal development of conduction system.
Naokata Sumitomo   +7 more
wiley   +1 more source

Betulin Protects Against Cardiac Hypertrophy by Improving AMPK/Nrf2‐Dependent Mitochondrial Function

open access: yesPhytotherapy Research, Volume 40, Issue 5, Page 2878-2894, May 2026.
Betulin effectively mitigates pressure overload‐induced cardiac hypertrophy in both Ang II‐infused and TAC‐operated mice. Mechanistically, betulin activated AMPK phosphorylation, promoted Nrf2 nuclear translocation, and upregulated antioxidant genes (HO‐1 and NQO‐1), thereby restoring mitochondrial function in cardiomyocytes.
Bei Zheng   +8 more
wiley   +1 more source

Immunopathology of cardiomyopathy in the experimental Chagas disease [PDF]

open access: yesMemórias do Instituto Oswaldo Cruz, 1999
The mechanisms by which Trypanosoma cruzi causes cardiomyopathy and induces neuronal destruction are discussed in this paper. The results suggest that autoimmunity in the chronic phase is the main cause of the progressive cardiac destruction, and that autoreactivity is restricted to the CD4+ T cell compartment.
Milena B. P. Soares   +1 more
openaire   +4 more sources

TNF‐α partially modulates the endothelial dysfunction during the acute phase of Trypanosoma cruzi infection

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 10, Page 2256-2272, May 2026.
Background and Purpose Whereas the effects of Trypanosoma cruzi (T. cruzi) infection are well‐characterised in the heart, its impact on the vasculature has received little attention. In this study, we investigated the effects of acute and chronic T. cruzi infection on vascular responsiveness and the underlying mechanisms.
Thales M. H. Dourado   +6 more
wiley   +1 more source

Analysis of collaboration and leadership at country level in research production on Chagas cardiomyopathy.

open access: yes, 2018
Analysis of collaboration and leadership at country level in research production on Chagas cardiomyopathy.
Alejandro Salinas (5410928)   +2 more
core   +1 more source

Screening for Trypanosoma cruzi infection (Chagas disease) in the Latin American population living with HIV in London

open access: yesHIV Medicine, Volume 27, Issue 5, Page 796-802, May 2026.
Abstract Background There are an estimated 2482 people born in Latin American countries receiving care for HIV in the United Kingdom. Although national guidance recommends screening for Trypanosoma cruzi infection (Chagas disease) in this population, there is no formal screening programme.
Natalie Elkheir   +18 more
wiley   +1 more source

Enhancing patient care: a multimodality strategy for dilated cardiomyopathy in Chagas disease [PDF]

open access: yesExploration of Cardiology
Chagas disease is a systemic illness characterized by acute and chronic phases. If untreated, it can lead to dysfunction of vital organs, notably the heart, ultimately resulting in heart failure.
Luigy Vasquez-Yeng   +8 more
doaj   +1 more source

T Cell Receptor Repertoires Across the Continuum of Vascular, Myocardial, and Age‐Related Diseases

open access: yesImmunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT Cardiovascular diseases (CVD) are shaped by a complex interplay with immune mechanisms. In particular, the distinct roles of antigen‐specific T cell mechanisms are emerging as critical determinants across a broad spectrum of conditions, ranging from atherosclerosis, myocardial infarction (MI), heart failure (HF), and myocarditis. Because these
Leon Richter   +3 more
wiley   +1 more source

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