Results 91 to 100 of about 12,135 (209)

Sex in Immune Cells and Parasitic Diseases — A Complex Relationship

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Epidemiological studies consistently show that many parasitic diseases affect males more frequently than females. These disparities are multifactorial, arising partly from gender‐specific behaviors that influence exposure risk and health‐seeking practices, especially in low‐ and middle‐income countries. Increasing evidence also highlights that
Barbara Honecker, Charlotte Sophie Hansen, Hanna Lotter   +2 more
wiley   +1 more source

The effect of beta-blockade on myocardial remodelling in Chagas' cardiomyopathy

Clinics, 2012
OBJECTIVE: Chagas' disease has spread throughout Latin America because of the high rate of migration among these countries. Approximately 30% of Chagas' patients will develop cardiomyopathy, and 10% of these will develop severe cardiac damage leading to ...
Walace de Souza Pimentel, Felix José Alvarez Ramires, Barbara Maria lanni, Vera Maria Cury Salemi, Angelina Morand Bianchi Bilate, Edecio Cunha-Neto, Adriana Morgan de Oliveira, Fábio Fernandes, Charles Mady   +8 more
doaj   +1 more source

The P2X7 Receptor and Its Relation to Neglected Tropical Diseases: Focusing on Chagas Disease

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Chagas disease, caused by Trypanosoma cruzi, is a neglected tropical disease (NTD) that can lead to severe cardiac complications, including chronic Chagas cardiomyopathy. While NTDs are caused by a variety of pathogens—such as protozoa, bacteria, viruses, and helminths, Chagas disease remains underexplored, particularly regarding host immune responses.
Caroline de Souza Ferreira Pereira, Robson Xavier Faria, Wei Wang   +2 more
wiley   +1 more source

Serum Proteomic Signature of Human Chagasic Patients for the Identification of Novel Potential Protein Biomarkers of Disease [PDF]

, 2012
Chagas disease is initiated upon infection by Trypanosoma cruzi. Among the health consequences is a decline in heart function, and the pathophysiological mechanisms underlying this manifestation are not well understood. To explore the possible mechanisms,
Garg, Nisha Jain, Gupta, Shivali, Nuñez Burgos, Federico, Nuñez, Sonia, Wen, Jian Jun, Zago, María Paola   +5 more
core   +1 more source

Medical treatment of cardiac arrhythmias in Chagas'heart disease [PDF]

, 1995
There are no controlled clinical trials evaluating drug therapy in patients with ventricular arrhythmias and chronic chagasic cardiomyopathy. Empirical treatment with disopyramide (400-1,000mg/d), phenytoin (4-6mg/d), mexiletine (600-1,200mg/d ...
De Paola, Angelo Amato Vincenzo, Gondin, Fernando Antonio Aquino, Hara, Vanderlei, Mendonça, Alayde   +3 more
core   +1 more source

Bufalin‐Induced Epithelial‐to‐Mesenchymal Transition in Kidney Epithelial Cells

Cell Biology International, Volume 49, Issue 12, Page 1764-1786, December 2025.
ABSTRACT The kidney plays a central role in fluid, electrolyte, and blood pressure regulation, processes tightly coupled to Na⁺/K⁺‐ATPase activity. Beyond its canonical transport function, Na⁺/K⁺‐ATPase also acts as a signaling receptor for cardiotonic steroids (CTSs) such as bufalin, which have been implicated in fibrosis and epithelial‐to‐mesenchymal
Gabriela Morais de Oliveira Barros, Kayo M. Bagri, Claudia Mermelstein, Luis Eduardo M. Quintas   +3 more
wiley   +1 more source

Cardiomyopathy protection in Chagas Disease [PDF]

World Journal of Cardiovascular Diseases, 2013
There is some published evidence suggesting micro vascular endothelial dysfunction and dysautonomia involvement in Chagas disease in association with cardiomyocyte changes favoring disease progression. The combined treatment between angiotensin converting enzyme (ACE) inhibitor drugs; Simvastatin, muscarinic antibody immunoadsorbent together with ...
Mitelman, Jorge E., Gimenez, Luisa
openaire   +2 more sources

Minimally Invasive Repair of Left Ventricular Aneurysm After Esophagectomy With Retrosternal Gastric Conduit: A Case Report

Clinical Case Reports, Volume 13, Issue 12, December 2025.
Preoperative CT and 3D reconstruction demonstrating an inferior left ventricular aneurysm in a patient with a retrosternal gastric conduit, highlighting the rationale for choosing a left mini‐thoracotomy approach. ABSTRACT In patients with prior esophagectomy and retrosternal gastric conduit, conventional sternotomy may be hazardous.
Junya Kitaura, Tomokuni Furukawa, Kazuki Maeda   +2 more
wiley   +1 more source

A Novel Predictive Score to Identify the Necessity for Epicardial Ventricular Tachycardia Ablation: EPI‐VT‐Score

Journal of Cardiovascular Electrophysiology, Volume 36, Issue 11, Page 2870-2877, November 2025.
The novel EPI‐VT‐Score accurately predicts the need for epicardial VT ablation using simple clinical, echocardiographic and ECG variables, optimizing patient selection and procedural outcomes. ABSTRACT Background Epicardial ventricular tachycardia (VT) ablation is a therapeutic option for drug‐refractory VT, particularly when endocardial ablation fails
Moneeb Khalaph, Denise Guckel, Nadica Trajkovska, Maxim Didenko, Mustapha El Hamriti, Martin Braun, Guram Imnadze, Philip Lucas, Thomas Fink, Vanessa Sciacca, Sebastian Beyer, Yuri Bocchini, Alessandro Guareschi, Arseniy Goncharov, Kawa Mohemed, Volker Rudolph, Christian Sohns, Philipp Sommer   +17 more
wiley   +1 more source

Angiotensin Receptor-Neprilysin Inhibition in Chagas Cardiomyopathy: Clinical Practice Update

Journal of Education, Health and Sport
Background: Chronic Chagas cardiomyopathy is an arrhythmogenic, fibrosis-prone form of heart failure that develops years after Trypanosoma cruzi infection. Standard therapy has largely been extrapolated from non-Chagas trials.
Katarzyna Skibicka, Weronika Wesołowska, Tomasz Skibicki, Robert Bujak   +3 more
doaj   +1 more source