Results 111 to 120 of about 12,135 (209)

Therapeutic effects of sphingosine kinase inhibitor N,N-dimethylsphingosine (DMS) in experimental chronic Chagas disease cardiomyopathy

Scientific Reports, 2017
Chagas disease cardiomyopathy is a parasite-driven inflammatory disease to which there are no effective treatments. Here we evaluated the therapeutic potential of N,N-dimethylsphingosine(DMS), which blocks the production of sphingosine-1-phosphate(S1P ...
Juliana Fraga Vasconcelos, Cássio Santana Meira, Daniela Nascimento Silva, Carolina Kymie Vasques Nonaka, Pâmela Santana Daltro, Simone Garcia Macambira, Pablo Daniel Domizi, Valéria Matos Borges, Ricardo Ribeiro-dos-Santos, Bruno Solano de Freitas Souza, Milena Botelho Pereira Soares   +10 more
doaj   +1 more source

Comparação do desfecho entre a cardiopatia chagásica e a miocardiopatia dilatada idiopática Comparison of outcome between Chagas cardiomyopathy and idiopathic dilated cardiomyopathy

Arquivos Brasileiros de Cardiologia, 2011
FUNDAMENTO: Pouco se sabe sobre o desfecho dos pacientes com cardiopatia chagásica, em comparação aos pacientes com miocardiopatia dilatada idiopática na era contemporânea. OBJETIVO: Comparar o desfecho dos pacientes chagásicos com insuficiência cardíaca
Amanda Pires Barbosa, Augusto Cardinalli Neto, Ana Paula Otaviano, Bianca Faria Rocha, Reinaldo Bulgarelli Bestetti   +4 more
doaj  

REACTIVATION OF CHAGAS DISEASE WITH CENTRAL NERVOUS SYSTEM INVOLVEMENT: CASE SERIES

Brazilian Journal of Infectious Diseases
Chagas disease, caused by Trypanosoma cruzi, remains an important public health problem in the Americas. Although the most prevalent chronic form is cardiac, central nervous system reactivation is rare but severe, particularly in immunosuppressed ...
Clara dos Reis Aguiar, Natália Soares Albuquerque, Claudia Murta de Oliveira, Isabela Rocha de Castro, Leandro Curi de Lima e Sousa   +4 more
doaj   +1 more source

2025 ACVIM Forum Research Abstract Program

Journal of Veterinary Internal Medicine, Volume 39, Issue 6, November/December 2025.
wiley   +1 more source

Sex Differences in Chagas Cardiomyopathy: a Comprehensive Review

Current Heart Failure Reports
Chagas cardiomyopathy (CCC) is a major cause of heart failure (HF) in Latin America, yet sex-specific differences in HF presentation and outcomes remain underexplored. This review summarizes current knowledge on clinical manifestations, HF phenotypes, and molecular mechanisms in women and men with CCC.Men with CCC more frequently present with severe HF,
Mansur, Antonio de Padua, Cunha-Neto, Edecio, Bestetti, Reinaldo Bulgarelli, Brochet, Pauline, Chevillard, Christophe, Pereira-Barretto, Antonio Carlos, Bocchi, Edimar Alcides   +6 more
openaire   +3 more sources

ISEV2025 Abstract Book

Journal of Extracellular Vesicles, Volume 14, Issue S1, October 2025.
wiley   +1 more source

Benznidazole for Chronic Chagas’ Cardiomyopathy

New England Journal of Medicine, 2016
Hamers, Raph L., van Gool, Tom, Goorhuis, Abraham   +2 more
openaire   +6 more sources

A Expressão Global da Doença de Chagas – Oportunidades Emergentes e Impacto em Portugal [PDF]

, 2012
Chagas disease, caused by the protozoan Trypanosoma cruzi is endemic in the countries of Central and South America. Despite vector control programs and other measures taken in the blood banks and maternity hospitals, it is estimated that there are about ...
Cortez, J, Ramos, E, Seixas, J, Valente, C, Vieira, A   +4 more
core  

Chagas Cardiomyopathy

Chagas disease (CD) is a major cause of cardiomyopathy in Latin America, and migration movements have now spread the disease worldwide. However, data regarding Chagas cardiomyopathy (CC) and the usefulness of echocardiography in non endemic countries are still scarce. We selected 485 patients in the chronic phase of CD from two Spanish settings.
Sánchez-Montalvá, Adrián||, Salvador, Fernando||, Rodríguez Palomares, José Fernando||, Sulleiro Igual, Elena||, Sao-Avilés, Augusto||, Roure, Sílvia, Valerio, Lluís||, Evangelista Masip, Arturo||, Molina Romero, Israel||   +8 more
openaire   +1 more source

Chagas, a Cardiomyopathy Emerging from Obscurity [PDF]

European Journal of Heart Failure, 2015
Westenbrink, B. Daan, Kingma, J. Herre
openaire   +3 more sources