Results 61 to 70 of about 12,135 (209)

A cardiac rehabilitation exercise program potentially inhibits progressive inflammation in patients with severe Chagas cardiomyopathy: A pilot single-arm clinical trial

Journal of Research in Medical Sciences, 2020
Background: Cardiac rehabilitation exerts anti-inflammatory effect on several cardiovascular diseases; however, these effects were not described for Chagas cardiomyopathy, which is associated with pro-inflammatory imbalance.
Luiz Fernando Rodrigues Junior, Fernanda de Souza Nogueira Sardinha Mendes, Vivian Liane Mattos Pinto, Paula Simplicio da Silva, Gilberto Marcelo Sperandio da Silva, Roberta Olmo Pinheiro, Andréa Silvestre de Sousa, Mauro Felippe Felix Mediano   +7 more
doaj   +1 more source

Importancia en el sistema de salud de la infección por Treponema pallidum, la enfermedad de Chagas y el virus de la inmunodeficiencia humana 1 en amerindios de Argentina: un estudio observacional [PDF]

, 2017
El objetivo de este trabajo fue estimar la prevalencia de Treponema pallidum, Trypanosoma cruzi y virus de la inmunodeficiencia humana (HIV-1) en 5 comunidades originarias de Argentina.
Berini, Carolina Andrea, Biglione, Mirna Marcela, de Rissio, Ana María, Delfino, Cecilia María, Eirin, Maria Emilia, Espejo, Rogelio, Gallo Vaulet, Maria Lucia, Malan, Richard, Pedrozo, Williams René, Puca, Alberto, Rodríguez Fermepin, Marcelo   +10 more
core   +2 more sources

Betulin Protects Against Cardiac Hypertrophy by Improving AMPK/Nrf2‐Dependent Mitochondrial Function

Phytotherapy Research, Volume 40, Issue 5, Page 2878-2894, May 2026.
Betulin effectively mitigates pressure overload‐induced cardiac hypertrophy in both Ang II‐infused and TAC‐operated mice. Mechanistically, betulin activated AMPK phosphorylation, promoted Nrf2 nuclear translocation, and upregulated antioxidant genes (HO‐1 and NQO‐1), thereby restoring mitochondrial function in cardiomyocytes.
Bei Zheng, Mingyang He, Haiying Wu, Tianjie Zhang, Yuxia Jiang, Chuanwei Xin, Meiling Zhang, Jiaqi He, Lulu Zheng   +8 more
wiley   +1 more source

TNF‐α partially modulates the endothelial dysfunction during the acute phase of Trypanosoma cruzi infection

British Journal of Pharmacology, Volume 183, Issue 10, Page 2256-2272, May 2026.
Background and Purpose Whereas the effects of Trypanosoma cruzi (T. cruzi) infection are well‐characterised in the heart, its impact on the vasculature has received little attention. In this study, we investigated the effects of acute and chronic T. cruzi infection on vascular responsiveness and the underlying mechanisms.
Thales M. H. Dourado, Wanessa M. C. Awata, Gustavo F. Pimenta, Barbara M. Marchetti, Maiara V. Providello, Sérgio De Albuquerque, Carlos R. Tirapelli   +6 more
wiley   +1 more source

Omega-3 supplementation on inflammatory markers in patients with chronic Chagas cardiomyopathy: a randomized clinical study

Nutrition Journal, 2017
Background Several studies have been focusing on the effect of omega-3 polyunsaturated fatty acids on modulation of inflammatory markers in several cardiopathies.
Paula Simplício da Silva, Mauro Felippe Felix Mediano, Gilberto Marcelo Sperandio da Silva, Patricia Dias de Brito, Claudia Santos de Aguiar Cardoso, Cristiane Fonseca de Almeida, Luiz Henrique Conde Sangenis, Roberta Olmo Pinheiro, Alejandro Marcel Hasslocher-Moreno, Pedro Emmanuel Alvarenga Americano do Brasil, Andrea Silvestre de Sousa   +10 more
doaj   +1 more source

Association of caspase-1 polymorphisms with Chagas cardiomyopathy among individuals in Santa Cruz, Bolivia

Revista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION: Trypanosoma cruzi (Tc) infection is usually acquired in childhood in endemic areas, leading to Chagas disease, which progresses to Chagas cardiomyopathy in 20-30% of infected individuals over decades.
Katherine Yih-Jia Fu, Roxana Zamudio, Jo Henderson-Frost, Alex Almuedo, Hannah Steinberg, Steven Joseph Clipman, Gustavo Duran, Rachel Marcus, Thomas Crawford, Daniel Alyesh, Rony Colanzi, Jorge Flores, Robert Hugh Gilman, Caryn Bern   +13 more
doaj   +1 more source

Clinical and echocardiographic predictors of mortality in chagasic cardiomyopathy - systematic review

Arquivos Brasileiros de Cardiologia, 2014
Diagnosis, prognosis and evaluation of death risk in Chagas cardiomyopathy still constitute a challenge due to the diversity of manifestations, which determine the importance of using echocardiography, tissue Doppler and biomarkers. To evaluate, within a
Clodoval de Barros Pereira Júnior, Brivaldo Markman Filho   +1 more
doaj   +1 more source

Chagas Disease Diagnostic Applications: Present Knowledge and Future Steps [PDF]

, 2016
Chagas disease, caused by the protozoan Trypanosoma cruzi, is a lifelong and debilitating illness of major significance throughout Latin America and an emergent threat to global public health.
Balouz, Virginia, Buscaglia, Carlos Andres, Fernandez Aguero, Maria Jose   +2 more
core   +1 more source

Screening for Trypanosoma cruzi infection (Chagas disease) in the Latin American population living with HIV in London

HIV Medicine, Volume 27, Issue 5, Page 796-802, May 2026.
Abstract Background There are an estimated 2482 people born in Latin American countries receiving care for HIV in the United Kingdom. Although national guidance recommends screening for Trypanosoma cruzi infection (Chagas disease) in this population, there is no formal screening programme.
Natalie Elkheir, Shivani Singh, Birgit Barbini, Lucy Campbell, Alice Sharp, Jacqueline O'Connell, Louise Terry, Margherita Bracchi, Javier Rubio, Nicolo Girometti, Mohammed Hassan, Hannah Davies, Frank A. Post, Laura Nabarro, Debbie Nolder, Geraldine O'Hara, Julie Fox, Peter L. Chiodini, David A. J. Moore   +18 more
wiley   +1 more source

T Cell Receptor Repertoires Across the Continuum of Vascular, Myocardial, and Age‐Related Diseases

Immunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT Cardiovascular diseases (CVD) are shaped by a complex interplay with immune mechanisms. In particular, the distinct roles of antigen‐specific T cell mechanisms are emerging as critical determinants across a broad spectrum of conditions, ranging from atherosclerosis, myocardial infarction (MI), heart failure (HF), and myocarditis. Because these
Leon Richter, João Dias‐Ferreira, Gustavo Campos Ramos, DiyaaElDin Ashour   +3 more
wiley   +1 more source