Results 61 to 70 of about 707 (123)

A Case of Heart Failure With Reduced Ejection Fraction Secondary to Dilated Cardiomyopathy due to Long‐Standing Untreated Acromegaly: A Case Report and Focused Literature Review

Clinical Case Reports, Volume 14, Issue 4, April 2026.
Echocardiographic findings in dilated cardiomyopathy secondary to untreated acromegaly. (A) Apical four‐chamber view showing biventricular and biatrial dilation. (B‐C) Colour Doppler demonstrating mitral, aortic, and tricuspid regurgitation. (D) Reduced global longitudinal strain (GLS: −6.5%), consistent with severe systolic dysfunction.
Cristian Orlando Porras Bueno, Nancy Muriel Herrera Leaño, María Juliana Soto Chávez, Darío Parra Prieto, Alejandro Mariño Correa   +4 more
wiley   +1 more source

The effect of beta-blockade on myocardial remodelling in Chagas' cardiomyopathy

Clinics, 2012
OBJECTIVE: Chagas' disease has spread throughout Latin America because of the high rate of migration among these countries. Approximately 30% of Chagas' patients will develop cardiomyopathy, and 10% of these will develop severe cardiac damage leading to ...
Walace de Souza Pimentel, Felix José Alvarez Ramires, Barbara Maria lanni, Vera Maria Cury Salemi, Angelina Morand Bianchi Bilate, Edecio Cunha-Neto, Adriana Morgan de Oliveira, Fábio Fernandes, Charles Mady   +8 more
doaj   +1 more source

Zhenyuan Solid Drink Ameliorates Inflammation and Oxidative Stress in Isoproterenol‐Induced Ischemic Myocardial Infarction via TLR4/NF‐κB Pathway and PI3K/AKT1/NRF2 Pathway in Rats

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
ZYSD exerts curative and preventive cardioprotection against isoproterenol‐induced myocardial infarction through synergistic interaction with probiotics, exerting antioxidant and anti‐inflammatory effects. ABSTRACT Zhenyuan Solid Drink (ZYSD) is a formulation consisting of 6 medicinal herbs that can be used as both food and medicinal materials in China.
Jiawen Huang, Tian Yu, Guoyi Li, Kechao Nie, Donghua Liu, Cong Meng, Xiaoling Shen, Linchun Fu, Liang Long, Zhuotao Fu, Zhitong Deng, Yingjie Hu   +11 more
wiley   +1 more source

The Intersection of m6A Methylation and Immune Response in PCOS: A Bioinformatics Perspective

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
N6‐methyladenosine RNA methylation regulators are intricately linked with the development of polycystic ovary syndrome (PCOS) and may influence immune cell infiltration in affected individuals. This study enhances our understanding of the molecular interactions in PCOS and suggests potential biomarkers for diagnosis and targets for therapeutic ...
Wenting Xu, Lingli Shi, Aifang Lu, Lijuan Cui, Haiqing Qian, Jiahui Wang, Mengyu Tang, Lili Zhu, Lihong Wang   +8 more
wiley   +1 more source

Early Onset Heart Failure due to RBM20 Variant: A Case Report Emphasizing Genetic Diagnosis and Arrhythmic Risk Stratification

Clinical Case Reports, Volume 14, Issue 1, January 2026.
Transthoracic echocardiography demonstrating biventricular dilatation. Parasternal long‐ and short‐axis views and apical four‐ and two‐chamber views show marked left ventricular dilatation with increased end‐diastolic volume, associated with right ventricular dilatation.
Cristian Orlando Porras Bueno, Cesar Augusto Balaguera, Alejandro Mariño Correa, Edward Andrés Cáceres Méndez   +3 more
wiley   +1 more source

Association between positive serology for COVID-19 and chagas cardiomyopathy progression: The SaMi-Trop project

Travel Medicine and Infectious Disease
Background: Chagas Disease (CD) can cause Chagas cardiomyopathy. The new coronavirus disease (COVID-19) also affects the cardiovascular system and may worsen Chagas cardiomyopathy.
Ariela Mota Ferreira, Léa Campos Oliveira-da Silva, Clareci Silva Cardoso, Cláudia Di Lorenzo Oliveira, Bruno Oliveira de Figueiredo Brito, Ana Luiza Bierrenbach, Ana Clara de Jesus Santos, Dardiane Santos Cruz, Sâmara Fernandes Leite, Andréia Brito Jesus, Renata Fiúza Damasceno, Maria Carmo Pereira Nunes, Israel Molina, Desirée Sant’ Anna Haikal, Ester Cerdeira Sabino, Antonio Luiz Pinho Ribeiro   +15 more
doaj   +1 more source

Activation of Human CD11b+ B1 B-Cells by Trypanosoma cruzi-Derived Proteins Is Associated With Protective Immune Response in Human Chagas Disease

Frontiers in Immunology, 2019
B-cells mediate humoral adaptive immune response via the production of antibodies and cytokines, and by inducing T-cell activation. These functions can be attributed to distinct B-cell subpopulations. Infection with Trypanosoma cruzi, the causative agent
Livia Silva Araújo Passos, Livia Silva Araújo Passos, Luísa Mourão Dias Magalhães, Luísa Mourão Dias Magalhães, Rodrigo Pinto Soares, Rodrigo Pinto Soares, Alexandre F. Marques, Marina Luiza Rodrigues Alves, Rodolfo Cordeiro Giunchetti, Rodolfo Cordeiro Giunchetti, Maria do Carmo Pereira Nunes, Kenneth J. Gollob, Kenneth J. Gollob, Walderez Ornelas Dutra, Walderez Ornelas Dutra, Walderez Ornelas Dutra   +15 more
doaj   +1 more source

Risk Score for Predicting 2‐Year Mortality in Patients With Chagas Cardiomyopathy From Endemic Areas: SaMi‐Trop Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Risk stratification of Chagas disease patients in the limited‐resource setting would be helpful in crafting management strategies. We developed a score to predict 2‐year mortality in patients with Chagas cardiomyopathy from remote endemic ...
Claudia Di Lorenzo Oliveira, Maria Carmo P. Nunes, Enrico Antonio Colosimo, Emilly Malveira de Lima, Clareci S. Cardoso, Ariela Mota Ferreira, Lea Campos de Oliveira, Carlos Henrique Valente Moreira, Ana Luiza Bierrenbach, Desireé Sant′Ana Haikal, Sérgio Viana Peixoto, Maria Fernanda Lima‐Costa, Ester Cerdeira Sabino, Antonio Luiz P. Ribeiro   +13 more
doaj   +1 more source

Lycopene's Role in Mitigating Obesity‐Induced Cardiac Remodeling: Insights Into Inflammatory and MMP‐2 Pathways

Molecular Nutrition &Food Research, Volume 70, Issue 2, 29 January 2026.
A. Consumption of a highsugar‐fat diet causes excess nutrients, hypertrophy and hyperplasia of adipocytes, causing obesity. Obesity leads to increased inflammatory levels in the heart, which stimulates greater activation of Metalloproteinase‐2 (MMP‐2), which has collagenolytic activity, degrading the collagen network in the heart, ultimately causing ...
Carol Cristina Vagula de Almeida de Silva, Artur Junio Togneri Ferron, Fabiane Valentini Francisqueti‐Ferron, Alexandre Ribeiro da Silva, Silmeia Garcia Zanati Bazan, Jéssica Leite Garcia, Dijon Henrique Salomé de Campos, Mariane Róvero Costa, Daniele Dantas, Heloysa Amaral da Silva, Janaina Paixão das Chagas Silva, Giselle Pinto Faria de Lopes, Bertha Furlan Polegato, Camila Renata Correa, Fernando Moreto, Ana Lucia Anjos Ferreira   +15 more
wiley   +1 more source

Antigen-Based Nano-Immunotherapy Controls Parasite Persistence, Inflammatory and Oxidative Stress, and Cardiac Fibrosis, the Hallmarks of Chronic Chagas Cardiomyopathy, in A Mouse Model of Trypanosoma cruzi Infection

Vaccines, 2020
Chagas cardiomyopathy is caused by Trypanosoma cruzi (Tc). We identified two candidate antigens (TcG2 and TcG4) that elicit antibodies and T cell responses in naturally infected diverse hosts.
Nandadeva Lokugamage, Subhadip Choudhuri, Carolina Davies, Imran Hussain Chowdhury, Nisha Jain Garg   +4 more
doaj   +1 more source