Results 11 to 20 of about 94,471 (252)
CMAJChagas disease persists as a global public health problem due to the high morbidity and mortality burden. Despite the possibility of a cure and advances in transmission control, epidemiological transformations, such as urbanisation and globalisation, and the emerging importance of oral and vertical transmission mean that Chagas disease should be ...
Billick MJ, Silverberg SL.
europepmc +6 more sources
Pediatrics In Review, 2016 Approximately 8 million people worldwide are infected by the protozoan parasite Trypanosoma cruzi, the causative agent of Chagas disease. After a latent period that can last years or decades, 10% to 30% of infected people develop serious complications, such as cardiomyopathy or gastrointestinal dysfunction.
Tustin, Aaron W., Bowman, Natalie M.
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Clinical Microbiology Reviews, 1992 Chagas' disease, caused by Trypanosoma cruzi, is an important cause of morbidity in many countries in Latin America. The important modes of transmission are by the bite of the reduviid bug and blood transfusion. The organism exists in three morphological forms: trypomastigotes, amastigotes, and epimastigotes.
H B, Tanowitz +5 more
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Postgraduate Medical Journal, 2006 Abstract Chagas disease is the clinical condition triggered by infection with the protozoan Trypanosoma cruzi. The infection is transmitted by triatomine insects while blood feeding on a human host. Field studies predict that one third of an estimated 18 million T cruzi-infected humans in Latin America will die of Chagas disease.
A R L, Teixeira +4 more
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Infectious Diseases of Poverty, 2021 Background Chagas disease is endemic in Latin America and, over the last few decades, due to population movements, the disease has spread to other continents. Early diagnosis and treatment are critical in terms of improving outcomes for those living with
María Romay-Barja +4 more
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Integrated control of chagas disease for its elimination as public health problem: A review [PDF]
, 2015 Chagas disease or American trypanosomiasis is, together with geohelminths, the neglected disease that causes more loss of years of healthy life due to disability in Latin America.
Segura, Elsa Leonor +1 more
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Congenital Chagas Disease in the United States: Cost Savings Through Maternal Screening [PDF]
, 2018 Chagas disease, caused by Trypanosoma cruzi, is transmitted by insect vectors through transfusions, transplants, insect feces in food, and from mother to child during gestation.
Bialek, Stephanie R. +3 more
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A protocol update for the Selenium Treatment and Chagasic Cardiomyopathy (STCC) trial
Trials, 2018 Several studies evaluating clinical forms of chronic Chagas disease show that about one-third of patients present cardiac involvement. Heart failure, sudden death and cardioembolic stroke are the main mechanisms of death in Chagas heart disease.
Marcelo Teixeira Holanda +24 more
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Novel cruzain inhibitors for the treatment of Chagas' disease. [PDF]
, 2012 The protozoan parasite Trypanosoma cruzi, the etiological agent of Chagas' disease, affects millions of individuals and continues to be an important global health concern.
Arkin, Michelle R +6 more
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Annals of Intensive Care, 2017 Background Early-onset ventilator-associated pneumonia (EO-VAP) is the leading cause of morbidity and mortality in comatose patients. However, VAP prevention bundles focus mainly on late-onset VAP and may be less effective in preventing EO-VAP in ...
Cássia Righy +4 more
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