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Arquivos Brasileiros de Cardiologia, 1999 Chagas’ disease is a protozoan infection caused by Trypanosoma cruzi and is mainly acquired by vectorial transmission in endemic areas, when infected excreta of Triatominae bugs are inoculated into the sting site or neighbouring mucous membranes of the victim.
Marin-Neto, José Antonio +2 more
openaire +6 more sources
Chagas disease in prehistory [PDF]
Anais da Academia Brasileira de Ciências, 2011 The classical hypothesis proposes that Chagas disease has been originated in the Andean region among prehistoric people when they started domesticating animals, changing to sedentary habits, and adopting agriculture. These changes in their way of life happened nearly 6,000 years ago.
Ferreira, Luiz F. +2 more
openaire +6 more sources
Clinical Microbiology Reviews, 1992 Chagas' disease, caused by Trypanosoma cruzi, is an important cause of morbidity in many countries in Latin America. The important modes of transmission are by the bite of the reduviid bug and blood transfusion. The organism exists in three morphological forms: trypomastigotes, amastigotes, and epimastigotes.
H B, Tanowitz +5 more
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WHF IASC Roadmap on Chagas Disease
Global Heart, 2020 Background: Chagas Disease is a neglected tropical disease caused by the protozoan Trypanosoma cruzi, with some of the most serious manifestations affecting the cardiovascular system.
L. E. Echeverría +19 more
semanticscholar +1 more source
Electrocardiogram in Chagas disease [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 2018 Since the initial descriptions of Chagas cardiomyopathy (ChCM), the electrocardiography has played a key role in patient evaluations. The diagnostic criterion of chronic ChCM is the presence of characteristic electrocardiographic (ECG) abnormalities in seropositive individuals, regardless of the presence of symptoms.
Brito, Bruno Oliveira de Figueiredo +1 more
openaire +6 more sources
Infectious Diseases of Poverty, 2021 Background Chagas disease is endemic in Latin America and, over the last few decades, due to population movements, the disease has spread to other continents. Early diagnosis and treatment are critical in terms of improving outcomes for those living with
María Romay-Barja +4 more
doaj +1 more source
Congenital Chagas Disease in the United States: Cost Savings Through Maternal Screening [PDF]
, 2018 Chagas disease, caused by Trypanosoma cruzi, is transmitted by insect vectors through transfusions, transplants, insect feces in food, and from mother to child during gestation.
Bialek, Stephanie R. +3 more
core +2 more sources
Frontiers in Medicine, 2023 Diagnosis of Trypanosoma cruzi (T. cruzi) infection in the chronic phase of Chagas disease (CD) is performed by serologic testing. Conventional tests are currently used with very good results but require time, laboratory infrastructure, and expertise ...
Jacqueline Araújo Domingos Iturra +11 more
doaj +1 more source
JAMA Network Open, 2020 Key Points Question What is the risk of developing cardiomyopathy among patients with the acute phase of Chagas infection or the indeterminate chronic form of Chagas disease?
S. Chadalawada +15 more
semanticscholar +1 more source
Novel cruzain inhibitors for the treatment of Chagas' disease. [PDF]
, 2012 The protozoan parasite Trypanosoma cruzi, the etiological agent of Chagas' disease, affects millions of individuals and continues to be an important global health concern.
Arkin, Michelle R +6 more
core +1 more source