Results 31 to 40 of about 113,289 (321)

Novel cruzain inhibitors for the treatment of Chagas' disease. [PDF]

open access: yes, 2012
The protozoan parasite Trypanosoma cruzi, the etiological agent of Chagas' disease, affects millions of individuals and continues to be an important global health concern.
Arkin, Michelle R   +6 more
core   +1 more source

Insights from quantitative and mathematical modelling on the proposed WHO 2030 goals for Chagas disease [version 1; peer review: 2 approved]

open access: yesGates Open Research, 2019
Chagas disease (CD) persists as one of the neglected tropical diseases (NTDs) with a particularly large impact in the Americas. The World Health Organization (WHO) recently proposed goals for CD elimination as a public health problem to be reached by ...
Collaborating Group on Chagas Disease Modelling
doaj   +1 more source

Detecting Areas of Potential High Prevalence of Chagas in Argentina [PDF]

open access: yes, 2020
A map of potential prevalence of Chagas disease (ChD) with high spatial disaggregation is presented. It aims to detect areas outside the Gran Chaco ecoregion (hyperendemic for the ChD), characterized by high affinity with ChD and high health vulnerability.
arxiv   +1 more source

International meeting: New diagnostic tests are urgently needed to treat patients with Chagas disease. [PDF]

open access: yes, 2008
Trypanosoma cruzi infection is often not detected early on or actively diagnosed, partly because most infected individuals are either asymptomatic or oligosymptomatic.
Campaign for Access to Essential Medicines
core   +3 more sources

Plasma-Derived Extracellular Vesicles as Potential Biomarkers in Heart Transplant Patient with Chronic Chagas Disease [PDF]

open access: yes, 2021
Chagas disease is emerging in countries to which it is not endemic. Biomarkers for earlier therapeutic response assessment in patients with chronic Chagas disease are needed.
Almeida, Igor Correia de   +11 more
core   +1 more source

Chagas disease [PDF]

open access: yesPostgraduate Medical Journal, 2006
Abstract Chagas disease is the clinical condition triggered by infection with the protozoan Trypanosoma cruzi. The infection is transmitted by triatomine insects while blood feeding on a human host. Field studies predict that one third of an estimated 18 million T cruzi-infected humans in Latin America will die of Chagas disease.
A R L, Teixeira   +4 more
openaire   +2 more sources

School‐based health and nutrition interventions addressing double burden of malnutrition and educational outcomes of adolescents in low‐ and middle‐income countries: A systematic review

open access: yesMaternal &Child Nutrition, EarlyView., 2023
Abstract School system is a promising platform for addressing all forms of malnutrition in adolescents. However, little is known about the impact of integrated school health and nutrition programmes on adolescent nutrition and educational outcomes in low‐ and middle‐income countries (LMICs).
Sachin Shinde   +3 more
wiley   +1 more source

Analyzing the Spread of Chagas Disease with Mobile Phone Data [PDF]

open access: yesIEEE/ACM ASONAM pp. 607-612, San Francisco CA, USA, August 18-21 (2016), 2017
We use mobile phone records for the analysis of mobility patterns and the detection of possible risk zones of Chagas disease in two Latin American countries. We show that geolocalized call records are rich in social and individual information, which can be used to infer whether an individual has lived in an endemic area. We present two case studies, in
arxiv   +1 more source

Cortactin: A universal host cytoskeletal target of Gram‐negative and Gram‐positive bacterial pathogens

open access: yesMolecular Microbiology, Volume 118, Issue 6, Page 623-636, December 2022., 2022
In host‐pathogen interactions, actin‐cytoskeletal dynamics play a crucial role in successful adherence, invasion, and intracellular motility by many intruding microbes. To achieve this goal, bacterial pathogens target major host regulators, one of which is the key actin‐binding protein and class‐II actin nucleation‐promoting factor cortactin.
Irshad Sharafutdinov   +4 more
wiley   +1 more source

Overdiagnosis of vaccine allergy: Skin testing and challenge at a public specialized unit (CRIE) in Rio de Janeiro, Brazil

open access: yesJournal of Allergy and Clinical Immunology: Global, 2023
Background: Vaccination is an extremely safe public health intervention, but rare IgE-mediated adverse events must be identified to avoid the risk of anaphylaxis in the event of reexposure.
Luciana Gomes Pedro Brandão, PhD, MSc, MD   +10 more
doaj  

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