Different serological cross-reactivity of Trypanosoma rangeli forms in Trypanosoma cruzi-infected patients sera [PDF]
, 2008 Background American Trypanosomiasis or Chagas disease is caused by Trypanosoma cruzi which currently infects approximately 16 million people in the Americas causing high morbidity and mortality.
de Moraes, Milene H. +7 more
core +3 more sources
A protocol update for the Selenium Treatment and Chagasic Cardiomyopathy (STCC) trial
Trials, 2018 Several studies evaluating clinical forms of chronic Chagas disease show that about one-third of patients present cardiac involvement. Heart failure, sudden death and cardioembolic stroke are the main mechanisms of death in Chagas heart disease.
Marcelo Teixeira Holanda +24 more
doaj +1 more source
Mortality among blood donors seropositive and seronegative for Chagas disease (1996-2000) in São Paulo, Brazil: A death certificate linkage study. [PDF]
PLoS Neglected Tropical Diseases, 2017 Individuals in the indeterminate phase of Chagas disease are considered to have mortality rates similar to those of the overall population. This study compares mortality rates among blood donors seropositive for Chagas disease and negative controls in ...
Ligia Capuani +7 more
doaj +1 more source
Access to diagnosis and treatment of Chagas disease/infection in endemic and non-endemic countries in the XXI century. [PDF]
, 2007 In this article, Médicos Sin Fronteras (MSF) Spain faces the challenge of selecting, piecing together, and conveying in the clearest possible way, the main lessons learnt over the course of the last seven years in the world of medical care for Chagas ...
Albajar-Vinas, P +4 more
core +4 more sources
Troponin in Chagas disease [PDF]
Brazilian Journal of Infectious Diseases, 2003 Chagas disease is still a major tropical diseasein Latin America, affecting 16 to 18 million people.About 6 million people are infected with thecausative organism, Trypanosoma cruzi , in Brazil[1]. However, it often remains for decades in itsindeterminate form, symptomless, with tissue injuryin about 30% of the cases, which eventually willevolve to ...
Aras, Roque +6 more
openaire +6 more sources
Longitudinal study of patients with chronic Chagas cardiomyopathy in Brazil (SaMi-Trop project): a cohort profile. [PDF]
, 2016 PurposeWe have established a prospective cohort of 1959 patients with chronic Chagas cardiomyopathy to evaluate if a clinical prediction rule based on ECG, brain natriuretic peptide (BNP) levels, and other biomarkers can be useful in clinical practice ...
Bierrenbach, Ana Luiza +10 more
core +3 more sources
COVID-19: Implications for People with Chagas Disease
Global Heart, 2020 As the global COVID-19 pandemic advances, it increasingly impacts those vulnerable populations who already bear a heavy burden of neglected tropical disease.
E. Zaidel +14 more
semanticscholar +1 more source
Annals of Intensive Care, 2017 Background Early-onset ventilator-associated pneumonia (EO-VAP) is the leading cause of morbidity and mortality in comatose patients. However, VAP prevention bundles focus mainly on late-onset VAP and may be less effective in preventing EO-VAP in ...
Cássia Righy +4 more
doaj +1 more source
Challenges in Chagas Disease Drug Development
Molecules, 2020 The protozoan parasite Trypanosoma cruzi causes Chagas disease, an important public health problem throughout Latin America. Current therapeutic options are characterised by limited efficacy, long treatment regimens and frequent toxic side-effects ...
A. Francisco +6 more
semanticscholar +1 more source
Current knowledge of Chagas-related heart disease among pediatric cardiologists in the United States
BMC Cardiovascular Disorders, 2021 Background Chagas disease is a pathogenic parasitic infection with approximately 8 million cases worldwide and greater than 300,000 cases in the United States (U.S.).
Sanchi Malhotra +4 more
doaj +1 more source