Results 51 to 60 of about 101,506 (305)

Antinociceptive and Anti‐inflammatory Effect of Nicandrin B Isolated From Datura ferox in Zebrafish

Chemistry &Biodiversity, EarlyView.
ABSTRACT Nicandrin B (Nic B), a withanolide isolated from Datura ferox leaves, was investigated for its antinociceptive and anti‐inflammatory effects in adult zebrafish (Danio rerio). Animals treated with Nic B (4, 20, and 40 mg/kg) showed no toxicity and maintained normal locomotor activity.
Jéssica Bezerra Maciel, Hortência Ribeiro Liberato, Antônio Wlisses da Silva, Maria Auxiliadora Solange Silva Gondim Pereira, Emanuela de Lima Rebouças, Francisco das Chagas L. Pinto, Matheus Nunes da Rocha, Maria Kueirislene Amâncio Ferreira, Janaina Serra Azul Monteiro Evangelista, Izabel Florindo Guedes, Marcia Machado Marinho, Emmanuel Silva Marinho, Andreia Ferreira de Castro Gomes, Otília Loiola Pessoa, Jane Eire Silva Alencar de Menezes, Hélcio Silva dos Santos   +15 more
wiley   +1 more source

Physical activity levels during COVID-19 pandemic and its associated factors in patients with Chagas disease

Frontiers in Medicine
BackgroundA better understanding of the consequences of the Coronavirus Disease 2019 (COVID-19) pandemic on lifestyle of patients with Chagas disease (ChD) is of paramount importance to facilitate the implementation of intervention strategies tailored to
Isis Gabrielli Gomes Xavier, Patrícia Mello Andrade, Rodrigo de Lima Vitor, Tayná Cruz Barros, Luciana Fernandes Portela, Marcelo Teixeira de Holanda, Luiz Henrique Conde Sangenis, Gilberto Marcelo Sperandio da Silva, Flavia Mazzoli-Rocha, Fernanda de Souza Nogueira Sardinha Mendes, Andréa Rodrigues da Costa, Marcel de Souza Borges Quintana, Alejandro Marcel Hasslocher-Moreno, Itauá Leston Araujo, Angela Cristina Verissimo Junqueira, Roberta Olmo Pinheiro, Ingebourg Georg, Vitor Barreto Paravidino, Vitor Barreto Paravidino, Tatiana Rehder Gonçalves, Roberto Magalhães Saraiva, Mauro Felippe Felix Mediano, Mauro Felippe Felix Mediano   +22 more
doaj   +1 more source

Identifying Current and Missing Knowledge in the Control of Pyrethroid-Resistant Triatoma Infestans, Vector of Chagas Disease [PDF]

, 2017
Triatomines are blood-sucking bugs that occur mainly in Latin America. They are vectors of Trypanosoma cruzi, the parasite that causes Chagas disease.
Picollo, Maria Ines, Roca Acevedo, Gonzalo   +1 more
core   +1 more source

Immunopathology of Chagas disease [PDF]

Memórias do Instituto Oswaldo Cruz, 1999
The main clinical forms of Chagas disease (acute, indeterminate and chronic cardiac) present strong evidences for the participation of the immune system on pathogenesis. Although parasite multiplication is evident during acute infection, the intense acute myocarditis of this phase exhibits clear ultrastructural signs of cell-mediated immune damage ...
openaire   +5 more sources

Chagas' Heart Disease [PDF]

Clinical Cardiology, 2000
AbstractChagas' disease is caused by a protozoan parasite, Trypanosoma cruzi, that is transmitted to humans through the feces of infected bloodsucking insects in endemic areas of Latin America, or occasionally by nonvectorial mechanisms, such as blood transfusion.
A, Rassi, A, Rassi, W C, Little
openaire   +3 more sources

Antimicrobial Activity and Chemical Constituents of Siparuna guianensis (Siparunaceae)

Chemistry &Biodiversity, EarlyView.
ABSTRACT Siparuna guianensis (Siparunaceae) is an Amazonian plant known by the popular name of Negramina. There are several reports of the use of this plant in folk medicine. In the present work, we decided to study its extracts, aiming at the isolation of compounds and verifying their antimicrobial activities.
Olência Mento Manuensa Vilanculo, Mayra Suelen da Silva Pinheiro, Luana Cardoso de Oliveira, Dayenne Alexa Araújo de Souza, Sandra Valeria Dias Cardoso, Sebastião da Cruz Silva, Patrícia Santana Barbosa Marinho, Andrey Moacir do Rosario Marinho   +7 more
wiley   +1 more source

Feeding and defecation behavior of Triatoma rubida (Uhler, 1894) (Hemiptera: Reduviidae) under laboratory conditions, and its potential role as a vector of chagas disease in Arizona, USA [PDF]

, 2011
Chagas disease is caused by the parasite Trypanosoma cruzi, which is transmitted to humans by blood-sucking triatomine insects. This disease is endemic throughout Mexico and Central and South America, but only a few autochthonous cases have been reported
Gregory, Teresa, Guerenstein, Pablo Gustavo, Hildebrand, John, Reisenman, Carolina Esther   +3 more
core   +1 more source

Chagas disease surgery [PDF]

Memórias do Instituto Oswaldo Cruz, 1999
The dilatations that occur in the body are classified according to different systems: (1) biliary: mega-gallbladder, mega-common bile duct; (2) cardiovascular: cardiomegaly; (3) urinary: megapelvis, megaureter, megabladder; (4) respiratory: bronchiectasis, megabronchus; (5) megapharynx (?); (6) megaesophagus; (7) megastomach; (8) achalasia of the ...
openaire   +5 more sources

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application

Chemistry &Biodiversity, EarlyView.
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade, Edson de O. Lima Filho, Caio F. Valadão, Luana da S. M. Forezi, Fernando de C. da Silva   +4 more
wiley   +1 more source

Elimination of Chagas disease transmission: perspectives

Memorias do Instituto Oswaldo Cruz, 2009
One hundred years after its discovery by Carlos Chagas, American trypanosomiasis, or Chagas disease, remains an epidemiologic challenge. Neither a vaccine nor an ideal specific treatment is available for most chronic cases.
João Carlos Pinto Dias
doaj   +1 more source