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Potential Role of Antioxidants as Adjunctive Therapy in Chagas Disease
Oxidative Medicine and Cellular Longevity, 2020 Chagas disease (CD) is one of the most important neglected tropical diseases in the American continent. Host-derived nitroxidative stress in response to Trypanosoma cruzi infection can induce tissue damage contributing to the progression of Chagas ...
Juana P. Sánchez-Villamil +4 more
semanticscholar +1 more source
Memorias do Instituto Oswaldo Cruz, 2014 Recognising the importance of Chagas disease in Brazil, Bambuí set up epidemiological surveillance for Chagas disease in 1974 and was the first municipality to do so.
Christiane Santos Matos +4 more
doaj +1 more source
Immune complexes in chronic Chagas disease patients are formed by exovesicles from Trypanosoma cruzi carrying the conserved MASP N-terminal region [PDF]
, 2017 The exovesicles (EVs) are involved in pathologic host-parasite immune associations and have been recently used as biomarkers for diagnosis of infectious diseases.
De Pablos, Luis Miguel +5 more
core +3 more sources
Autochthonous Chagas Disease — Missouri, 2018
MMWR. Morbidity and mortality weekly report, 2020 On December 13, 2017, the Missouri Department of Health and Senior Services (MDHSS) was notified of a suspected case of Chagas disease in a Missouri woman.
G. Turabelidze +6 more
semanticscholar +1 more source
Chagas' disease and AIDS [PDF]
Kinetoplastid Biology and Disease, 2004 Chagas' disease caused by Trypanosoma cruzi is an opportunistic infection in the setting of HIV/AIDS. Some individuals with HIV and chronic T. cruzi infection may experience a reactivation, which is most commonly manifested by meningoencephalitis. A reactivation myocarditis is the second most common manifestation.
Louis M. Weiss +2 more
openaire +3 more sources
Treatment and seroconversion in a cohort of children suffering from recent chronic Chagas infection in Yoro, Honduras [PDF]
, 2009 Between 1999-2002, Médécins Sans Frontières-Spain implemented a project seeking to determine the efficacy and safety of benznidazole in the treatment of recent chronic Chagas disease in a cohort of seropositive children in the Yoro Department, Honduras ...
Bassets, Glòria +9 more
core +4 more sources
The history of Chagas disease [PDF]
Parasites & Vectors, 2014 The ancestor of Trypanosome cruzi was probably introduced to South American via bats approximately 7-10 million years ago. When the first humans arrived in the New World, a sylvatic cycle of Chagas disease was then already well established. Paleoparasitological data suggests that human American trypanosomiasis originated in the Andean area when people ...
openaire +6 more sources
Canine Trypanosoma cruzi infection in the Bolivian Chaco [PDF]
, 2018 A cross-sectional study on Trypanosoma cruzi was carried out in 2013 to evaluate the role of dogs as possible source of infection for humans in two rural communities of the highly endemic Bolivian Chaco (Bartolo, Chuquisaca Department, n = 57 dogs; and ...
Bartoloni, Alessandro +9 more
core +2 more sources
Annals of Hepatology, 2017 Background Cirrhosis remains the most frequent liver-related cause of death worldwide and we aimed to evaluate its burden in Brazil from 2000 to 2012.Material and methods The Brazilian National Death Registry was analyzed from 2000 to 2012.
Hugo Perazzo +7 more
doaj +1 more source
Funding for Chagas Disease: A 10-Year (2009–2018) Survey
Tropical Medicine and Infectious Disease, 2020 Chagas disease was discovered in 1909 by the Brazilian scientist Carlos Chagas. After more than 110 years, many outcomes have been achieved in all research fields; however, Chagas disease remains a serious public health problem, mainly in Latin America ...
L. Sangenito +2 more
semanticscholar +1 more source